#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:A0R4I6	uniprotkb:A0R4I6	intact:EBI-9099369|ensemblbacteria:ABK73202	intact:EBI-9099369|ensemblbacteria:ABK73202	psi-mi:a0r4i6_mycs2(display_long)|uniprotkb:purB(gene name)|psi-mi:purB(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:MSMEG_5847(locus name)	psi-mi:a0r4i6_mycs2(display_long)|uniprotkb:purB(gene name)|psi-mi:purB(display_short)|uniprotkb:Adenylosuccinase(gene name synonym)|uniprotkb:MSMEG_5847(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Banerjee et al. (2014)	imex:IM-22087|pubmed:24479855	taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)")	taxid:246196(mycs2)|taxid:246196("Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-9099367|imex:IM-22087-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_890074.1|interpro:IPR019468|interpro:IPR020557|interpro:IPR000362(Fumarate lyase)|interpro:IPR022761|interpro:IPR008948(L-Aspartase-like)|interpro:IPR004769(Adenylosuccinate lyase)|rcsb pdb:4NLE|ensemblbacteria:ABK73202(transcript)|ensemblbacteria:MSMEG_5847(gene)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")	refseq:YP_890074.1|interpro:IPR019468|interpro:IPR020557|interpro:IPR000362(Fumarate lyase)|interpro:IPR022761|interpro:IPR008948(L-Aspartase-like)|interpro:IPR004769(Adenylosuccinate lyase)|rcsb pdb:4NLE|ensemblbacteria:ABK73202(transcript)|ensemblbacteria:MSMEG_5847(gene)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")	rcsb pdb:4NLE	-	-	figure legend:t1 f3|comment:"X-ray crystal structure of Mycobacterium smegmatis apo-adenylosuccinate lyase  (ASL)  with a partially ordered active site loop was determined at 2.16 Å resolution.  The structure  suggests that His149, Lys285 and Ser279 are functionally important. The low  catalytic  activity observed for M. smegmatis and M. tuberculosis ASLs is consistent with  their slow growth rate"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2014/01/27	2014/10/16	rogid:B1SoydL8wWvKIeBiWyd332BICCM246196	rogid:B1SoydL8wWvKIeBiWyd332BICCM246196	intact-crc:53C99FA522E481D4|rigid:3Pj+KO8hiNZ7yQeyeOqDBs3lzgY	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)