#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q6AYA5	uniprotkb:P14562	intact:EBI-9316198|ensembl:ENSRNOP00000008677	intact:EBI-916562|uniprotkb:P97620|ensembl:ENSRNOP00000026580	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:lamp1_rat(display_long)|uniprotkb:120 kDa lysosomal membrane glycoprotein(gene name synonym)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:Lamp1(gene name)|psi-mi:Lamp1(display_short)|uniprotkb:Lamp-1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316196|imex:IM-22615-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	rgd:2989|refseq:NP_036989.1|ensembl:ENSRNOG00000019629(gene)|ensembl:ENSRNOT00000026580(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0044754"(autolysosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|reactome:R-RNO-6798695|refseq:XP_017455483.1	go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome)	-	-	figure legend:f2a sf2a sf5a sf6b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2014/03/27	2014/10/16	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	rogid:2mCfYIdewLVD+Tur5waxSU9muhE10116	intact-crc:2D770EC342552ACA|rigid:frFO+b/HWevrvji/cRfBMd/N1ls	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q6AYA5	uniprotkb:Q63560	intact:EBI-9316198|ensembl:ENSRNOP00000008677	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316224|imex:IM-22615-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	go:"GO:0033267"(obsolete axon part)|go:"GO:0030425"(dendrite)	-	-	figure legend:sf6b|comment:"double immunofluorescence shows predominant  microtubule-like staining of MAP6 in dendrites and axons  and vesicular staining in the soma with some overlap with  TMEM106B-positive vesicles (Supplementary Fig S6B)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-hippocampus)|taxid:10116(Hippocampus of rat brain)	-	2014/03/27	2014/10/16	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	intact-crc:B06CA1CE13808157|rigid:HDJVGzL35sFZDUlJeD7UW6IE8MA	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q63560	uniprotkb:Q6AYA5	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	intact:EBI-9316198|ensembl:ENSRNOP00000008677	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316287|imex:IM-22615-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	-	-	-	figure legend:f4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/03/27	2014/10/16	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	intact-crc:C3AD24E5AF44E757|rigid:HDJVGzL35sFZDUlJeD7UW6IE8MA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63560	uniprotkb:Q6AYA5	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	intact:EBI-9316198|ensembl:ENSRNOP00000008677	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316291|imex:IM-22615-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	-	-	-	figure legend:f4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/03/27	2014/10/16	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	intact-crc:8D600E43E504AA00|rigid:HDJVGzL35sFZDUlJeD7UW6IE8MA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63560	uniprotkb:Q6AYA5	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	intact:EBI-9316198|ensembl:ENSRNOP00000008677	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316295|imex:IM-22615-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	-	-	-	figure legend:sf6a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/03/27	2014/10/16	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	intact-crc:E320062728947ED8|rigid:HDJVGzL35sFZDUlJeD7UW6IE8MA	false	-	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q6AYA5	uniprotkb:Q96JE9-1	intact:EBI-9316198|ensembl:ENSRNOP00000008677	intact:EBI-9316459|ensembl:ENSP00000307093	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:q96je9-1(display_long)|uniprotkb:N-STOP(isoform synonym)|uniprotkb:Neuronal-STOP(isoform synonym)|uniprotkb:MAP6(gene name)|psi-mi:MAP6(display_short)|uniprotkb:KIAA1878(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316433|imex:IM-22615-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	intact:EBI-9316441(isoform-parent)|ensembl:ENSG00000171533(gene)|ensembl:ENST00000304771(transcript)	-	-	-	figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/03/27	2014/10/16	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	rogid:azKypJOoIZuTldplWlQYh7Ebb3I9606	intact-crc:C887F386EFCFA825|rigid:E7gEWJiqOPI8ewv0+Fx30iODs7Y	false	green fluorescent protein tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q6AYA5	uniprotkb:Q63560	intact:EBI-9316198|ensembl:ENSRNOP00000008677	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316425|imex:IM-22615-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	-	-	-	figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2014/03/27	2014/10/16	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	intact-crc:E141A26E158CC383|rigid:HDJVGzL35sFZDUlJeD7UW6IE8MA	false	green fluorescent protein tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q63560	uniprotkb:P09527	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	intact:EBI-916225|uniprotkb:Q4AEF6|ensembl:ENSRNOP00000016432	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:rab7a_rat(display_long)|uniprotkb:Rab7a(gene name)|psi-mi:Rab7a(display_short)|uniprotkb:Ras-related protein p23(gene name synonym)|uniprotkb:Ras-related protein BRL-RAS(gene name synonym)|uniprotkb:Rab7(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316475|imex:IM-22615-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	rgd:61908|refseq:NP_076440.1|ensembl:ENSRNOG00000012247(gene)|ensembl:ENSRNOT00000016432(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043195"(terminal bouton)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045453"(bone resorption)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0061724"(lipophagy)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P09527|rcsb pdb:1VG0|rcsb pdb:1VG1|rcsb pdb:1VG8|rcsb pdb:1VG9|reactome:R-RNO-2132295|reactome:R-RNO-6798695|reactome:R-RNO-8854214|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-9035034|refseq:XP_006236911.1	go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome)	-	-	figure legend:f4d|comment:"To further support the biological relevance of the interaction  between TMEM106B and MAP6, we performed subcellular fractionation  of rat brain on a discontinuous iodixanol density gradient.  While ßIII-tubulin was broadly distributed over the whole gradient,  TMEM106B and MAP6 levels peaked in endosomal/lysosomal  fractions (marker protein Rab7) supporting close contact of the two  proteins in the same cellular compartment (Fig 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/03/27	2014/10/16	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rogid:lppyS2rWzk4Iax3nOHVdHiA0ceg10116	intact-crc:2671492F9BCC60ED|rigid:831vV72x5kXL/+kjj19OZDv2Jc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q63560	uniprotkb:Q6AYA5	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	intact:EBI-9316198|ensembl:ENSRNOP00000008677	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:t106b_rat(display_long)|uniprotkb:Tmem106b(gene name)|psi-mi:Tmem106b(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Schwenk et al. (2014)	imex:IM-22615|pubmed:24357581	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-9316475|imex:IM-22615-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	refseq:NP_001004267.1|rgd:1303037|ensembl:ENSRNOG00000006206(gene)|ensembl:ENSRNOT00000008677(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0007040"(lysosome organization)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR009790(Protein of unknown function DUF1356)	go:"GO:0005770"(late endosome)|go:"GO:0005764"(lysosome)	-	-	figure legend:f4d|comment:"To further support the biological relevance of the interaction  between TMEM106B and MAP6, we performed subcellular fractionation  of rat brain on a discontinuous iodixanol density gradient.  While ßIII-tubulin was broadly distributed over the whole gradient,  TMEM106B and MAP6 levels peaked in endosomal/lysosomal  fractions (marker protein Rab7) supporting close contact of the two  proteins in the same cellular compartment (Fig 4D)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2014/03/27	2014/10/16	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rogid:gdeR/Vzm1JCiggwxfcYyn9Da9eM10116	intact-crc:2671492F9BCC60ED|rigid:831vV72x5kXL/+kjj19OZDv2Jc0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)