#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P36107 uniprotkb:Q06346-PRO_0000409445 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-9084891 psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:q06346-pro_0000409445(display_long)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym)|uniprotkb:YDR367W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084900|imex:IM-22013-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 intact:EBI-38431(chain-parent) - - chain-seq-start:1|chain-seq-end:135 figure legend:Fig. 6A, 7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:OqH1ABaD95YtJxFHZp4FvAU/sQ8559292 intact-crc:4CBF8DE1074536D7|rigid:LFF3grdwajzZevx7mCmAynWwa1k false ha tag:?-? mutation disrupting interaction strength:103-103|green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36107 uniprotkb:Q06346 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-38431|uniprotkb:Q06999|uniprotkb:D6VSZ8|ensemblfungi:YDR367W psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:kei1_yeast(display_long)|uniprotkb:YDR367W(locus name)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084883|imex:IM-22013-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 refseq:NP_010655.1|sgd:S000002775|dip:DIP-8823N|ensemblfungi:YDR367W(gene)|ensemblfungi:YDR367W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|go:"GO:0070917"(inositol phosphoceramide synthase regulator activity)|interpro:IPR013862(Protein of unknown function DUF1753, Golgi) - - crc64:4EC6A3FF541FC6F5 figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:GoZpizhmzMFEsefKm6tMZDpss4M559292 intact-crc:51EEAD737842DC3C|rigid:uveEMRK/6qMJu7G/OLZeKKAYzK4 false ha tag:?-? green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36107 uniprotkb:Q06346-PRO_0000409446 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-9084910 psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:q06346-pro_0000409446(display_long)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym)|uniprotkb:YDR367W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084908|imex:IM-22013-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 intact:EBI-38431(chain-parent) - - chain-seq-start:136|chain-seq-end:221 figure legend:Fig. 6B, 7E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:GSKe43vABvD8gOQ+lVdXm48wSQs559292 intact-crc:A0F2E4A870E6AA0F|rigid:+S7nInd8ZIvNSTOr//XsO5X+EKo false ha tag:?-? green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36107 uniprotkb:Q06346 intact:EBI-2046036|uniprotkb:D6VXT3|uniprotkb:Q92324|ensemblfungi:YKL004W intact:EBI-38431|uniprotkb:Q06999|uniprotkb:D6VSZ8|ensemblfungi:YDR367W psi-mi:aur1_yeast(display_long)|uniprotkb:YKL004W(locus name)|uniprotkb:AUR1(gene name)|psi-mi:AUR1(display_short)|uniprotkb:"Phosphatidylinositol:ceramide phosphoinositol transferase"(gene name synonym)|uniprotkb:Aureobasidin A resistance protein(gene name synonym) psi-mi:kei1_yeast(display_long)|uniprotkb:YDR367W(locus name)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084875|imex:IM-22013-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012922.1|sgd:S000001487|dip:DIP-7196N|mint:P36107|ensemblfungi:YKL004W(gene)|ensemblfungi:YKL004W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0045140"(inositol phosphoceramide synthase activity)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|interpro:IPR000326(Phosphatidic acid phosphatase type 2/haloperoxidase)|interpro:IPR026841|interpro:IPR036938 refseq:NP_010655.1|sgd:S000002775|dip:DIP-8823N|ensemblfungi:YDR367W(gene)|ensemblfungi:YDR367W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|go:"GO:0070917"(inositol phosphoceramide synthase regulator activity)|interpro:IPR013862(Protein of unknown function DUF1753, Golgi) - - crc64:4EC6A3FF541FC6F5 figure legend:Fig. 6A, 7D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2014/01/14 2014/10/16 rogid:xAYM/Tmh0vH9boXai27Tlko4u/k559292 rogid:GoZpizhmzMFEsefKm6tMZDpss4M559292 intact-crc:F5ABBA43252A2A76|rigid:uveEMRK/6qMJu7G/OLZeKKAYzK4 false ha tag:?-? mutation disrupting interaction strength:103-103|green fluorescent protein tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q06346 uniprotkb:P32074 intact:EBI-38431|uniprotkb:Q06999|uniprotkb:D6VSZ8|ensemblfungi:YDR367W intact:EBI-4891|ensemblfungi:YNL287W|uniprotkb:D6W0Q6 psi-mi:kei1_yeast(display_long)|uniprotkb:YDR367W(locus name)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym) psi-mi:copg_yeast(display_long)|uniprotkb:SEC21(gene name)|psi-mi:SEC21(display_short)|uniprotkb:YNL287W(locus name)|uniprotkb:N0543(orf name)|uniprotkb:Gamma-coat protein(gene name synonym) psi-mi:"MI:0096"(pull down) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084933|imex:IM-22013-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010655.1|sgd:S000002775|dip:DIP-8823N|ensemblfungi:YDR367W(gene)|ensemblfungi:YDR367W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|go:"GO:0070917"(inositol phosphoceramide synthase regulator activity)|interpro:IPR013862(Protein of unknown function DUF1753, Golgi) go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|ensemblfungi:YNL287W(gene)|ensemblfungi:YNL287W_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|refseq:NP_014112.1|sgd:S000005231|dip:DIP-1611N|mint:P32074|go:"GO:0030126"(COPI vesicle coat)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|reactome:R-SCE-6807878|reactome:R-SCE-6811434 - crc64:4EC6A3FF541FC6F5 crc64:99DC7D737D4EF761 figure legend:Fig. 9D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/14 2014/10/16 rogid:GoZpizhmzMFEsefKm6tMZDpss4M559292 rogid:uAs2hcx4DNS58qP1YDaUKgqZQm0559292 intact-crc:ADA33617128587B5|rigid:kDvqGpmPVtKEhLuFbVtRkVHo224 false glutathione s tranferase tag:n-n|sufficient binding region:176-221 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q06346 uniprotkb:P53622 intact:EBI-38431|uniprotkb:Q06999|uniprotkb:D6VSZ8|ensemblfungi:YDR367W intact:EBI-4860|uniprotkb:Q07595|uniprotkb:D6VRK3|ensemblfungi:YDL145C psi-mi:kei1_yeast(display_long)|uniprotkb:YDR367W(locus name)|uniprotkb:KEI1(gene name)|psi-mi:KEI1(display_short)|uniprotkb:KEX2-cleavable protein essential for inositol phosphorylceramide synthesis(gene name synonym) psi-mi:copa_yeast(display_long)|uniprotkb:COP1(gene name)|psi-mi:COP1(display_short)|uniprotkb:RET1(gene name synonym)|uniprotkb:SEC33(gene name synonym)|uniprotkb:YDL145C(locus name)|uniprotkb:D1578(orf name)|uniprotkb:SOO1(gene name synonym)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:Retrieval from endoplasmic reticulum protein 1(gene name synonym)|uniprotkb:Secretory protein 22(gene name synonym)|uniprotkb:Suppressor of osmo-sensitivity 1(gene name synonym) psi-mi:"MI:0096"(pull down) Sato et al. (2009) pubmed:19726565|imex:IM-22013 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-9084933|imex:IM-22013-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010655.1|sgd:S000002775|dip:DIP-8823N|ensemblfungi:YDR367W(gene)|ensemblfungi:YDR367W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006673"(inositol phosphoceramide metabolic process)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0070916"(inositol phosphoceramide synthase complex)|go:"GO:0070917"(inositol phosphoceramide synthase regulator activity)|interpro:IPR013862(Protein of unknown function DUF1753, Golgi) refseq:NP_010136.1|sgd:S000002304|dip:DIP-2582N|mint:P53622|ensemblfungi:YDL145C(gene)|ensemblfungi:YDL145C_mRNA(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011044(Quinoprotein amine dehydrogenase, beta chain-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|rcsb pdb:3MKQ|rcsb pdb:3MV2|rcsb pdb:3MV3|rcsb pdb:6U3W|reactome:R-SCE-6807878|reactome:R-SCE-6811434 - crc64:4EC6A3FF541FC6F5 crc64:D3589073106F5570 figure legend:Fig. 9D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2014/01/14 2014/10/16 rogid:GoZpizhmzMFEsefKm6tMZDpss4M559292 rogid:H88Vc2BQq2FQnwCVPb+/hq7beNU559292 intact-crc:ADA33617128587B5|rigid:kDvqGpmPVtKEhLuFbVtRkVHo224 false glutathione s tranferase tag:n-n|sufficient binding region:176-221 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)