#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0096"(pull down) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671392|imex:IM-22164-1|mint:MINT-8434259 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434333(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434261(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:f1a f1d f1e|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:B389EFAE007F4BBE|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:56-65(MINT-8434341)|glutathione s tranferase tag:?-?(MINT-8434338) flag tag:?-?(MINT-8434344)|binding-associated region:1231-1292(MINT-8434372) - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671427|imex:IM-22164-2|mint:MINT-8434351 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434353(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434359(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:st1 f2c f3b f3c f3d f4a f4b sf2a sf2f|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:5C074DE89347CA5E|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434354) binding-associated region:1231-1292(MINT-8434368) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671456|imex:IM-22164-3|mint:MINT-8434379 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434388(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434381(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:t1 f3a sf1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:68.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:7F89E02DC27EA369|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434391) binding-associated region:1231-1292(MINT-8434382) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671476|imex:IM-22164-4|mint:MINT-8434409 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434412(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434416(identity) - - - comment:homomint|comment:domino|comment:mint|figure legend:t1 sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:46.5x10^-6(molar) 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:949E2393A7E74C9B|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:40-60(MINT-8434413) binding-associated region:1231-1292(MINT-8434417) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671544|imex:IM-22164-7|mint:MINT-8434461 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434470(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434464(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:862.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:94628FC3AB6B59A0|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434471) binding-associated region:51-60(MINT-8434465)|mutation decreasing interaction:58-58(MINT-8434467) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671520|imex:IM-22164-6|mint:MINT-8434443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434446(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434451(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:253.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:F868E03D5CB5E28F|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434447) mutation decreasing interaction:57-57(MINT-8434452)|binding-associated region:51-60(MINT-8434454) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671496|imex:IM-22164-5|mint:MINT-8434424 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434431(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434427(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:980.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:4C6914792A5D5522|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434432) mutation decreasing interaction:56-56(MINT-8434439)|binding-associated region:51-60(MINT-8434428) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671568|imex:IM-22164-8|mint:MINT-8434479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434487(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434482(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:588.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:20637B87DD83EE0D|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434490)|mutation decreasing interaction:59-59(MINT-8434488) binding-associated region:1231-1292(MINT-8434483) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671615|imex:IM-22164-10|mint:MINT-8434517 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434519(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434526(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:139.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:6CD7F324C69C0C02|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434522)|mutation decreasing interaction:1247-1247(MINT-8434520) binding-associated region:51-60(MINT-8434527) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671639|imex:IM-22164-11|mint:MINT-8434535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434542(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434538(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:2DC2C1172A37DA04|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434545)|mutation disrupting interaction:1248-1248(MINT-8434543) binding-associated region:51-60(MINT-8434539) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671592|imex:IM-22164-9|mint:MINT-8434496 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434499(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434505(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:A906E33A8AE7D931|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434500) mutation disrupting interaction:1240-1240(MINT-8434513)|binding-associated region:1231-1292(MINT-8434506) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671686|imex:IM-22164-13|mint:MINT-8434572 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434582(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434575(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:99DB5C9409CB6064|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434583) binding-associated region:1231-1292(MINT-8434576)|mutation disrupting interaction:1286-1286(MINT-8434579) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9BX66 uniprotkb:O15265 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671709|imex:IM-22164-14|mint:MINT-8434711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434713(identity) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434720(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:78.1x10^-6(molar) 2013/08/22 2014/10/16 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 intact-crc:8FF1D5FF29EC9659|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:1231-1292(MINT-8434716)|mutation decreasing interaction:1281-1281(MINT-8434714) binding-associated region:51-60(MINT-8434721) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8671662|imex:IM-22164-12|mint:MINT-8434554 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434557(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434561(identity) - - - figure legend:t1|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:571.0x10^-6(molar) 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:2CF24669F9EE3864|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false binding-associated region:51-60(MINT-8434558) mutation decreasing interaction:1266-1266(MINT-8434562)|binding-associated region:1231-1292(MINT-8434564) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O15265 uniprotkb:Q9BX66 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Jiang et al. (2013) mint:MINT-8434210|pubmed:23892081|imex:IM-22164 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8671742|imex:IM-22164-15|mint:MINT-8434598 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2|mint:MINT-8434601(identity) refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S|mint:MINT-8434600(identity) go:"GO:0016604"(nuclear body) - - figure legend:f5|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2013/08/22 2014/10/16 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 intact-crc:67AC70DAEC027D4F|rigid:VIqpHqFNSkASCuDfJXJPIS1yyMo false green fluorescent protein tag:?-?(MINT-8434607) binding-associated region:1231-1292(MINT-8434615)|flag tag:?-?(MINT-8434612)|mutation decreasing interaction:1266-1266(MINT-8434634) - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0707"(anti tag immunostaining)