#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39946 uniprotkb:P39946 intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name) psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name) psi-mi:"MI:0071"(molecular sieving) Huang et al. (2012) pubmed:22939623|imex:IM-17821 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6379129|imex:IM-17821-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N - crc64:E667E4BA7602FB3B crc64:E667E4BA7602FB3B figure legend:Supp. Fig. 2E|comment:"Cleavable ZZ and His were removed prior to this expt. Pretreatment of Lis1 with LDS (4%) to denature Lis1 abolishes formation of the crosslinked dimer."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/21 2014/10/16 rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292 rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292 intact-crc:DB9B5C7C760B65A7|rigid:vZg6uOrC70v9t22KDJFXp06U97g false tag:c-c tag:c-c 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39946 uniprotkb:P39946 intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W intact:EBI-12838|uniprotkb:D6W2W9|ensemblfungi:YOR269W psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name) psi-mi:lis1_yeast(display_long)|uniprotkb:PAC1(gene name)|psi-mi:PAC1(display_short)|uniprotkb:nudF homolog(gene name synonym)|uniprotkb:LIS1(gene name synonym)|uniprotkb:Lissencephaly-1 homolog(gene name synonym)|uniprotkb:YOR269W(locus name) psi-mi:"MI:0030"(cross-linking study) Huang et al. (2012) pubmed:22939623|imex:IM-17821 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-6305074|imex:IM-17821-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N ensemblfungi:YOR269W(gene)|ensemblfungi:YOR269W_mRNA(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007097"(nuclear migration)|go:"GO:0030473"(nuclear migration along microtubule)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051301"(cell division)|go:"GO:0070840"(dynein complex binding)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|rcsb pdb:5VH9|rcsb pdb:5VLJ|refseq:NP_014912.1|sgd:S000005795|mint:P39946|dip:DIP-1485N - crc64:E667E4BA7602FB3B crc64:E667E4BA7602FB3B figure legend:Supp. Fig. 2E|comment:"Cleavable ZZ and His were removed prior to this expt. Pretreatment of Lis1 with LDS (4%) to denature Lis1 abolishes formation of the crosslinked dimer."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2012/09/21 2014/10/16 rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292 rogid:tyU5fR5V8csklk2QqAQHt3Mmz7c559292 intact-crc:19E7E9CEE0918540|rigid:vZg6uOrC70v9t22KDJFXp06U97g false tag:c-c tag:c-c 2 0 psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)