#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8QG92	uniprotkb:P51142	intact:EBI-6257549|uniprotkb:Q6DDX1	intact:EBI-6257503	psi-mi:dct1b_xenla(display_long)|uniprotkb:Dapper1a(gene name synonym)|uniprotkb:dact1-b(gene name)|psi-mi:dact1-b(display_short)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0423"(in-gel kinase assay)	Teran et al. (2009)	pubmed:19440376	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6257547	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR024843|interpro:IPR024848	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:2A|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:XFHnRU/BNw9CY6Qx+olGmYJwxBM8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:B4C63F78F25EFB28|rigid:KYUvxidkJucqr5wnmnCxtPCrzmA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QG92	uniprotkb:Q06486	intact:EBI-6257549|uniprotkb:Q6DDX1	intact:EBI-2910316|ensembl:ENSRNOP00000051819|uniprotkb:Q99KK4	psi-mi:dct1b_xenla(display_long)|uniprotkb:Dapper1a(gene name synonym)|uniprotkb:dact1-b(gene name)|psi-mi:dact1-b(display_short)	psi-mi:kc1d_rat(display_long)|uniprotkb:Csnk1d(gene name)|psi-mi:Csnk1d(display_short)|uniprotkb:Hckid(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym)	psi-mi:"MI:0423"(in-gel kinase assay)	Teran et al. (2009)	pubmed:19440376	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6257547	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR024843|interpro:IPR024848	ensembl:ENSRNOG00000036676(gene)|ensembl:ENSRNOT00000054936(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q06486|rcsb pdb:1CKJ|reactome:R-RNO-204005|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6791226|reactome:R-RNO-8854518|rcsb pdb:1CKI|rgd:71031|refseq:NP_620691.2	-	-	caution:"Rat CKIalpha lacking its autoinhibtory domain was used (cannot not be mapped to UniProt."	figure legend:2A|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:XFHnRU/BNw9CY6Qx+olGmYJwxBM8355	rogid:FAsEbnos4akvB+YK6EAFbAsBtTo10116	intact-crc:B4C63F78F25EFB28|rigid:KYUvxidkJucqr5wnmnCxtPCrzmA	false	-	35s radiolabel:?-?|sufficient binding region:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8QG92	uniprotkb:P51142	intact:EBI-6257549|uniprotkb:Q6DDX1	intact:EBI-6257503	psi-mi:dct1b_xenla(display_long)|uniprotkb:Dapper1a(gene name synonym)|uniprotkb:dact1-b(gene name)|psi-mi:dact1-b(display_short)	psi-mi:dvl2_xenla(display_long)|uniprotkb:dvl2(gene name)|psi-mi:dvl2(display_short)|uniprotkb:dsh(gene name synonym)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:Xdsh(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Teran et al. (2009)	pubmed:19440376	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-6257584	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0046329"(negative regulation of JNK cascade)|interpro:IPR024843|interpro:IPR024848	go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009986"(cell surface)|go:"GO:0022008"(neurogenesis)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045545"(syndecan binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050821"(protein stabilization)|go:"GO:0060026"(convergent extension)|go:"GO:0060027"(convergent extension involved in gastrulation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060271"(cilium assembly)|go:"GO:0090630"(activation of GTPase activity)|rcsb pdb:1L6O|rcsb pdb:2F0A|rcsb pdb:3FY5|mint:P51142|refseq:NP_001084096.1|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR024580|interpro:IPR003351(Dishevelled protein)|interpro:IPR001158(DIX)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR029071|interpro:IPR038207|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390	-	-	-	figure legend:4A|antagonist:CKI-delta|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2012/07/30	2014/10/16	rogid:XFHnRU/BNw9CY6Qx+olGmYJwxBM8355	rogid:9sVQXQeFtWj/Vjbc/ABl3kHS5dE8355	intact-crc:FCBD46542C84B5EF|rigid:DRKdPTNz74YRUppLNKFdOaLR4IY	false	myc tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)