#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P07251 uniprotkb:P00830 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926825|mint:MINT-7711060|imex:IM-15707-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711063(identity) sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711064(identity) - crc64:E8041D289B924696 crc64:EDFF256826F68F0C figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292 intact-crc:F7C42E3C83DAD613|rigid:ePJihMlgIZvJrss9vG8+qitxG0Q false - his tag:?-?(MINT-7711252) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P07251 uniprotkb:P38077 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 intact:EBI-3271|uniprotkb:Q54AF5|uniprotkb:Q76MT6|uniprotkb:D6VQ39|ensemblfungi:YBR039W psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:atpg_yeast(display_long)|uniprotkb:ATP3(gene name)|psi-mi:ATP3(display_short)|uniprotkb:YBR039W(locus name)|uniprotkb:YBR0408(orf name)|uniprotkb:F-ATPase gamma subunit(gene name synonym)|uniprotkb:ATP3a(gene name synonym)|uniprotkb:ATP3b(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926825|mint:MINT-7711060|imex:IM-15707-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711063(identity) refseq:NP_009595.1|sgd:S000000243|dip:DIP-3035N|mint:P38077|ensemblfungi:YBR039W(gene)|ensemblfungi:YBR039W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711065(identity) - crc64:E8041D289B924696 crc64:ADC71F3C1E0CDF91 figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 rogid:TTC2MR+Y1+qYe5qaaq/OQfDzAAA559292 intact-crc:F7C42E3C83DAD613|rigid:ePJihMlgIZvJrss9vG8+qitxG0Q false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P07251 uniprotkb:P36955 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926825|mint:MINT-7711060|imex:IM-15707-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711063(identity) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711062(identity) - crc64:E8041D289B924696 - figure legend:f1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 intact-crc:F7C42E3C83DAD613|rigid:ePJihMlgIZvJrss9vG8+qitxG0Q false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:P21306 uniprotkb:P07251 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926928|mint:MINT-7711313|imex:IM-15707-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711326(identity) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711321(identity) - - crc64:E8041D289B924696 comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 intact-crc:26E793672C26661C|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P21306 uniprotkb:P00830 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926928|mint:MINT-7711313|imex:IM-15707-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711326(identity) sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711317(identity) - - crc64:EDFF256826F68F0C comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292 intact-crc:26E793672C26661C|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - his tag:?-?(MINT-7711318) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P21306 uniprotkb:Q12165 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W intact:EBI-7926894|intact:MINT-2781010|uniprotkb:D6VRY4|ensemblfungi:YDL004W psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:atpd_yeast(display_long)|uniprotkb:ATP16(gene name)|psi-mi:ATP16(display_short)|uniprotkb:YDL004W(locus name)|uniprotkb:YD8119.03(orf name)|uniprotkb:D2935(orf name)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926928|mint:MINT-7711313|imex:IM-15707-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711326(identity) refseq:NP_010280.1|mint:Q12165|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|ensemblfungi:YDL004W(gene)|ensemblfungi:YDL004W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|dip:DIP-3032N|sgd:S000002162|mint:MINT-7711325(identity) - - comment:mint|function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits" comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 rogid:8AZH7r4kvh2pvm949Y3p7Ml5RzE559292 intact-crc:26E793672C26661C|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P21306 uniprotkb:P38077 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W intact:EBI-3271|uniprotkb:Q54AF5|uniprotkb:Q76MT6|uniprotkb:D6VQ39|ensemblfungi:YBR039W psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:atpg_yeast(display_long)|uniprotkb:ATP3(gene name)|psi-mi:ATP3(display_short)|uniprotkb:YBR039W(locus name)|uniprotkb:YBR0408(orf name)|uniprotkb:F-ATPase gamma subunit(gene name synonym)|uniprotkb:ATP3a(gene name synonym)|uniprotkb:ATP3b(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926928|mint:MINT-7711313|imex:IM-15707-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711326(identity) refseq:NP_009595.1|sgd:S000000243|dip:DIP-3035N|mint:P38077|ensemblfungi:YBR039W(gene)|ensemblfungi:YBR039W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711315(identity) - - crc64:ADC71F3C1E0CDF91 comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 rogid:TTC2MR+Y1+qYe5qaaq/OQfDzAAA559292 intact-crc:26E793672C26661C|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P21306 uniprotkb:P36955 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:"MI:0071"(molecular sieving) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926928|mint:MINT-7711313|imex:IM-15707-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711326(identity) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711323(identity) - - - comment:homomint|comment:mint|figure legend:fs3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/02/22 2014/10/16 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 intact-crc:26E793672C26661C|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - fluorescent protein tag:?-?(MINT-7711327) - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P36955 uniprotkb:Q12165 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 intact:EBI-7926894|intact:MINT-2781010|uniprotkb:D6VRY4|ensemblfungi:YDL004W psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:atpd_yeast(display_long)|uniprotkb:ATP16(gene name)|psi-mi:ATP16(display_short)|uniprotkb:YDL004W(locus name)|uniprotkb:YD8119.03(orf name)|uniprotkb:D2935(orf name)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926987|mint:MINT-7711083|imex:IM-15707-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711085(identity) refseq:NP_010280.1|mint:Q12165|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|ensemblfungi:YDL004W(gene)|ensemblfungi:YDL004W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|dip:DIP-3032N|sgd:S000002162|mint:MINT-7711089(identity) - - comment:mint|function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits" comment:homomint|comment:mint|figure legend:f2a; f2b; f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.51x10^-9(molar) 2010/02/22 2014/10/16 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 rogid:8AZH7r4kvh2pvm949Y3p7Ml5RzE559292 intact-crc:B4BD1ADF3DC881F0|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36955 uniprotkb:P21306 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926987|mint:MINT-7711083|imex:IM-15707-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711085(identity) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711090(identity) - - - comment:homomint|comment:mint|figure legend:f2a; f2b; f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.51x10^-9(molar) 2010/02/22 2014/10/16 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 intact-crc:B4BD1ADF3DC881F0|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36955 uniprotkb:P07251 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926987|mint:MINT-7711083|imex:IM-15707-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711085(identity) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711086(identity) - - crc64:E8041D289B924696 comment:homomint|comment:mint|figure legend:f2a; f2b; f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.51x10^-9(molar) 2010/02/22 2014/10/16 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 intact-crc:B4BD1ADF3DC881F0|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36955 uniprotkb:P38077 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 intact:EBI-3271|uniprotkb:Q54AF5|uniprotkb:Q76MT6|uniprotkb:D6VQ39|ensemblfungi:YBR039W psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:atpg_yeast(display_long)|uniprotkb:ATP3(gene name)|psi-mi:ATP3(display_short)|uniprotkb:YBR039W(locus name)|uniprotkb:YBR0408(orf name)|uniprotkb:F-ATPase gamma subunit(gene name synonym)|uniprotkb:ATP3a(gene name synonym)|uniprotkb:ATP3b(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926987|mint:MINT-7711083|imex:IM-15707-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711085(identity) refseq:NP_009595.1|sgd:S000000243|dip:DIP-3035N|mint:P38077|ensemblfungi:YBR039W(gene)|ensemblfungi:YBR039W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711088(identity) - - crc64:ADC71F3C1E0CDF91 comment:homomint|comment:mint|figure legend:f2a; f2b; f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.51x10^-9(molar) 2010/02/22 2014/10/16 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 rogid:TTC2MR+Y1+qYe5qaaq/OQfDzAAA559292 intact-crc:B4BD1ADF3DC881F0|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P36955 uniprotkb:P00830 intact:EBI-2932733|ensembl:ENSP00000254722|uniprotkb:Q13236|uniprotkb:Q2TU83|uniprotkb:Q96CT1|uniprotkb:Q96R01|uniprotkb:Q9BWA4|uniprotkb:F1T092 intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W psi-mi:pedf_human(display_long)|uniprotkb:SERPINF1(gene name)|psi-mi:SERPINF1(display_short)|uniprotkb:PEDF(gene name synonym)|uniprotkb:Serpin F1(gene name synonym)|uniprotkb:EPC-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 35 protein(gene name synonym)|uniprotkb:PIG35(orf name) psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7926987|mint:MINT-7711083|imex:IM-15707-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0043203"(axon hillock)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0042698"(ovulation cycle)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033832|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1IMV|go:"GO:1901652"(response to peptide)|ensembl:ENSG00000132386(gene)|ensembl:ENST00000254722(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007568"(aging)|go:"GO:0007614"(short-term memory)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0042470"(melanosome)|refseq:NP_001316832.1|refseq:NP_002606.3|mint:MINT-7711085(identity) sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711087(identity) - - crc64:EDFF256826F68F0C comment:homomint|comment:mint|figure legend:f2a; f2b; f3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.51x10^-9(molar) 2010/02/22 2014/10/16 rogid:z1Q9Z9NYIqetmghdOghk604Ftgs9606 rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292 intact-crc:B4BD1ADF3DC881F0|rigid:+qfTBRo4vJP+oh8kL5cT+1+RH2Y false - his tag:?-?(MINT-7711249) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:Q12165 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-7926894|intact:MINT-2781010|uniprotkb:D6VRY4|ensemblfungi:YDL004W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpd_yeast(display_long)|uniprotkb:ATP16(gene name)|psi-mi:ATP16(display_short)|uniprotkb:YDL004W(locus name)|uniprotkb:YD8119.03(orf name)|uniprotkb:D2935(orf name)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927043|mint:MINT-7711113|imex:IM-15707-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711115(identity) refseq:NP_010280.1|mint:Q12165|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|ensemblfungi:YDL004W(gene)|ensemblfungi:YDL004W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|dip:DIP-3032N|sgd:S000002162|mint:MINT-7711119(identity) - - comment:mint|function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits" figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.95x10^-7(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:8AZH7r4kvh2pvm949Y3p7Ml5RzE559292 intact-crc:D4323EC787D2869E|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false binding-associated region:103-560(MINT-7711123) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P38077 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3271|uniprotkb:Q54AF5|uniprotkb:Q76MT6|uniprotkb:D6VQ39|ensemblfungi:YBR039W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpg_yeast(display_long)|uniprotkb:ATP3(gene name)|psi-mi:ATP3(display_short)|uniprotkb:YBR039W(locus name)|uniprotkb:YBR0408(orf name)|uniprotkb:F-ATPase gamma subunit(gene name synonym)|uniprotkb:ATP3a(gene name synonym)|uniprotkb:ATP3b(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927043|mint:MINT-7711113|imex:IM-15707-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711115(identity) refseq:NP_009595.1|sgd:S000000243|dip:DIP-3035N|mint:P38077|ensemblfungi:YBR039W(gene)|ensemblfungi:YBR039W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711118(identity) - - crc64:ADC71F3C1E0CDF91 figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.95x10^-7(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:TTC2MR+Y1+qYe5qaaq/OQfDzAAA559292 intact-crc:D4323EC787D2869E|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false binding-associated region:103-560(MINT-7711123) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P00830 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927043|mint:MINT-7711113|imex:IM-15707-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711115(identity) sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711117(identity) - - crc64:EDFF256826F68F0C figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.95x10^-7(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292 intact-crc:D4323EC787D2869E|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false binding-associated region:103-560(MINT-7711123) his tag:?-?(MINT-7711246) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P07251 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927043|mint:MINT-7711113|imex:IM-15707-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711115(identity) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711116(identity) - - crc64:E8041D289B924696 figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.95x10^-7(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 intact-crc:D4323EC787D2869E|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false binding-associated region:103-560(MINT-7711123) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P21306 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927043|mint:MINT-7711113|imex:IM-15707-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711115(identity) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711120(identity) - - - figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:1.95x10^-7(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 intact-crc:D4323EC787D2869E|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false binding-associated region:103-560(MINT-7711123) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:Q12165 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-7926894|intact:MINT-2781010|uniprotkb:D6VRY4|ensemblfungi:YDL004W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpd_yeast(display_long)|uniprotkb:ATP16(gene name)|psi-mi:ATP16(display_short)|uniprotkb:YDL004W(locus name)|uniprotkb:YD8119.03(orf name)|uniprotkb:D2935(orf name)|uniprotkb:F-ATPase delta subunit(gene name synonym) psi-mi:"MI:0405"(competition binding) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927121|mint:MINT-7711286|imex:IM-15707-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711288(identity) refseq:NP_010280.1|mint:Q12165|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|interpro:IPR036771|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|ensemblfungi:YDL004W(gene)|ensemblfungi:YDL004W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|dip:DIP-3032N|sgd:S000002162|mint:MINT-7711290(identity) - - comment:mint|function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits" figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:11.8x10^9(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:8AZH7r4kvh2pvm949Y3p7Ml5RzE559292 intact-crc:22F535CBF79184FF|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P21306 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3257|uniprotkb:D6W399|ensemblfungi:YPL271W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atp5e_yeast(display_long)|uniprotkb:ATP15(gene name)|psi-mi:ATP15(display_short)|uniprotkb:P0345(orf name)|uniprotkb:YPL271W(locus name) psi-mi:"MI:0405"(competition binding) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927121|mint:MINT-7711286|imex:IM-15707-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711288(identity) refseq:NP_015052.1|sgd:S000006192|ensemblfungi:YPL271W(gene)|ensemblfungi:YPL271W_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR006721(ATPase, F1 complex, epsilon subunit, mitochondrial)|interpro:IPR036742|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|dip:DIP-3031N|reactome:R-SCE-163210|reactome:R-SCE-8949613|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:4B2Q|rcsb pdb:6CP3|rcsb pdb:6CP6|mint:MINT-7711289(identity) - - - figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:11.8x10^9(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:TuGFNjLIdx3rnpgV0WxIWcjSOmg559292 intact-crc:22F535CBF79184FF|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P38077 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3271|uniprotkb:Q54AF5|uniprotkb:Q76MT6|uniprotkb:D6VQ39|ensemblfungi:YBR039W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpg_yeast(display_long)|uniprotkb:ATP3(gene name)|psi-mi:ATP3(display_short)|uniprotkb:YBR039W(locus name)|uniprotkb:YBR0408(orf name)|uniprotkb:F-ATPase gamma subunit(gene name synonym)|uniprotkb:ATP3a(gene name synonym)|uniprotkb:ATP3b(gene name synonym) psi-mi:"MI:0405"(competition binding) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927121|mint:MINT-7711286|imex:IM-15707-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711288(identity) refseq:NP_009595.1|sgd:S000000243|dip:DIP-3035N|mint:P38077|ensemblfungi:YBR039W(gene)|ensemblfungi:YBR039W_mRNA(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005756"(mitochondrial proton-transporting ATP synthase, central stalk)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711291(identity) - - crc64:ADC71F3C1E0CDF91 figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:11.8x10^9(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:TTC2MR+Y1+qYe5qaaq/OQfDzAAA559292 intact-crc:22F535CBF79184FF|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P00830 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3242|uniprotkb:D6VWU0|ensemblfungi:YJR121W psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpb_yeast(display_long)|uniprotkb:ATP2(gene name)|psi-mi:ATP2(display_short)|uniprotkb:J2041(orf name)|uniprotkb:YJR121W(locus name) psi-mi:"MI:0405"(competition binding) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927121|mint:MINT-7711286|imex:IM-15707-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711288(identity) sgd:S000003882|refseq:NP_012655.3|dip:DIP-3028N|mint:P00830|ensemblfungi:YJR121W(gene)|ensemblfungi:YJR121W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711292(identity) - - crc64:EDFF256826F68F0C figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:11.8x10^9(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:XA14lgBJ4D0nrBpMQw5tsc4aByU559292 intact-crc:22F535CBF79184FF|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false - his tag:?-?(MINT-7711299) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P00747 uniprotkb:P07251 intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938 intact:EBI-3234|uniprotkb:Q92449|ensemblfungi:YBL099W|uniprotkb:D6VPQ6 psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short) psi-mi:atpa_yeast(display_long)|uniprotkb:ATP1(gene name)|psi-mi:ATP1(display_short)|uniprotkb:YBL0827(orf name)|uniprotkb:YBL099W(locus name) psi-mi:"MI:0405"(competition binding) Notari et al. (2010) pubmed:20412062|imex:IM-15707|mint:MINT-7711031|mint:fj-09-1208.r1|doi:10.1111/j.1742-4658.2010.07641 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7927121|mint:MINT-7711286|imex:IM-15707-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205|mint:MINT-7711288(identity) ensemblfungi:YBL099W(gene)|ensemblfungi:YBL099W_mRNA(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043531"(ADP binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|refseq:NP_009453.2|sgd:S000000195|dip:DIP-3025N|mint:P07251|interpro:IPR038376|rcsb pdb:2HLD|rcsb pdb:2WPD|rcsb pdb:2XOK|rcsb pdb:3FKS|rcsb pdb:3OE7|rcsb pdb:3OEE|rcsb pdb:3OEH|rcsb pdb:3OFN|rcsb pdb:3ZIA|rcsb pdb:3ZRY|rcsb pdb:4B2Q|rcsb pdb:6B8H|rcsb pdb:6CP3|rcsb pdb:6CP6|reactome:R-SCE-163210|reactome:R-SCE-8949613|mint:MINT-7711293(identity) - - crc64:E8041D289B924696 figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) ic50:11.8x10^9(molar) 2010/02/22 2014/10/16 rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606 rogid:yqbEHfcYrXujvE9wfeN4KyeOHD8559292 intact-crc:22F535CBF79184FF|rigid:WH69xzSMf0nDkJWBOPZ/fer2F+c false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)