#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38742 uniprotkb:P39923 intact:EBI-24336|uniprotkb:D3DKU5|ensemblfungi:YHL023C intact:EBI-12212|uniprotkb:Q6B264|uniprotkb:D3DLI8|ensemblfungi:YEL062W psi-mi:npr3_yeast(display_long)|uniprotkb:Required for meiotic nuclear division protein 11(gene name synonym)|uniprotkb:NPR3(gene name)|psi-mi:NPR3(display_short)|uniprotkb:RMD11(gene name synonym)|uniprotkb:YHL023C(locus name) psi-mi:npr2_yeast(display_long)|uniprotkb:NPR2(gene name)|psi-mi:NPR2(display_short)|uniprotkb:YEL062W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2009) pubmed:19521502|imex:IM-19221 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650295|imex:IM-19221-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011840.1|sgd:S000001015|dip:DIP-2087N|ensemblfungi:YHL023C(gene)|ensemblfungi:YHL023C_mRNA(transcript)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990130"(GATOR1 complex)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR005365(Protein of unknown function UPF0171) ensemblfungi:YEL062W(gene)|ensemblfungi:YEL062W_mRNA(transcript)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0015824"(proline transport)|go:"GO:0015840"(urea transport)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0042493"|go:"GO:0097042"(extrinsic component of fungal-type vacuolar membrane)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1990130"(GATOR1 complex)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR009348(Nitrogen permease regulator 2)|refseq:NP_010852.4|sgd:S000000788|dip:DIP-1985N - crc64:8580F0C58982D51E crc64:58CA4983B0BAF7BA figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/04/28 2014/10/16 rogid:SggeLz0lEc9k12q/Zoq/AIfdyPE559292 rogid:YP7irpUKVZ19aKcUDQY0kKyjHbU559292 intact-crc:88666F7443EB2491|rigid:/Zz7gjyw9bfhSMBXkKY7hWuJxQ4 false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12980 uniprotkb:Q8WTW4 intact:EBI-2650314|uniprotkb:Q1W6H0|uniprotkb:Q4TT56|uniprotkb:Q92469|uniprotkb:D3DU40|ensembl:ENSP00000478273 intact:EBI-1043552|uniprotkb:Q9Y249|uniprotkb:Q9Y497|ensembl:ENSP00000232501|uniprotkb:A8K831|uniprotkb:Q6FGS2 psi-mi:nprl3_human(display_long)|uniprotkb:MARE(gene name synonym)|uniprotkb:NPRL3(gene name)|psi-mi:NPRL3(display_short)|uniprotkb:C16orf35(gene name synonym)|uniprotkb:CGTHBA(gene name synonym)|uniprotkb:Alpha-globin regulatory element-containing gene protein(gene name synonym)|uniprotkb:Protein CGTHBA(gene name synonym)|uniprotkb:-14 gene protein(gene name synonym)|uniprotkb:Nitrogen permease regulator 3-like protein(gene name synonym) psi-mi:nprl2_human(display_long)|uniprotkb:NPRL2(gene name)|psi-mi:NPRL2(display_short)|uniprotkb:Gene 21 protein(gene name synonym)|uniprotkb:TUSC4(gene name synonym)|uniprotkb:Tumor suppressor candidate 4(gene name synonym)|uniprotkb:Nitrogen permease regulator 2-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Neklesa et al. (2009) pubmed:19521502|imex:IM-19221 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2650310|imex:IM-19221-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070818.1|ensembl:ENSG00000103148(gene)|ensembl:ENST00000611875(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0060021"(roof of mouth development)|go:"GO:1990130"(GATOR1 complex)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR005365(Protein of unknown function UPF0171)|rcsb pdb:6CES|rcsb pdb:6CET|reactome:R-HSA-9639288|dip:DIP-62051N ensembl:ENSG00000114388(gene)|ensembl:ENST00000232501(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006995"(cellular response to nitrogen starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:1990130"(GATOR1 complex)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR009348(Nitrogen permease regulator 2)|rcsb pdb:6CES|rcsb pdb:6CET|reactome:R-HSA-9639288|refseq:NP_006536.3|dip:DIP-50746N - - - comment:Upon immunoprecipitation with anti-myc antibodies, only NPRL3 immunoprecipitates contained HA-NPRL2, demonstrating that NPRL2 and NPRL3 also form a complex.|figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/04/28 2014/10/16 rogid:SesntEp9nxFuoCGuZ06jHWqueek9606 rogid:SisXpfhPK3ANV4KYGsNgfxhWDa89606 intact-crc:B91C929663E4811D|rigid:hNwj6WsC7NmtsCg56ujQk5B4vXc false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)