#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96RK4 uniprotkb:Q9BXC9 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q8N3I7 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q8IWZ6 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-1806001|uniprotkb:Q4W5P8|uniprotkb:Q8N581|uniprotkb:Q9NVI4|ensembl:ENSP00000264499 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:bbs7_human(display_long)|uniprotkb:BBS7(gene name)|psi-mi:BBS7(display_short)|uniprotkb:BBS2L1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_060660.2|refseq:NP_789794.1|dip:DIP-46566N|ensembl:ENSG00000138686(gene)|ensembl:ENST00000264499(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|reactome:R-HSA-5620922|go:"GO:0034464"(BBSome) psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:8Czybdr0ILmxLq6yP0gyNPilfzE9606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q8NFJ9 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q15154 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q3SYG4 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q96RK4 uniprotkb:Q8TAM2 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-2892638|uniprotkb:Q86SY0|uniprotkb:Q86TV9|uniprotkb:Q86U26|uniprotkb:Q8NDH9|uniprotkb:Q96DG8|uniprotkb:A6NFG2|uniprotkb:B3KWA5|uniprotkb:Q67B97 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:ttc8_human(display_long)|uniprotkb:TTC8(gene name)|psi-mi:TTC8(display_short)|uniprotkb:BBS8(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 8 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892705|imex:IM-14959-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007411"(axon guidance)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034464"(BBSome)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0048560"(establishment of anatomical structure orientation)|go:"GO:0050893"(sensory processing)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0061326"(renal tubule development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR028796|interpro:IPR019734|refseq:NP_653197.2|refseq:NP_938051.1|refseq:NP_938052.1|reactome:R-HSA-5620922|refseq:NP_001275710.1|refseq:NP_001275711.1|refseq:NP_001275712.1|dip:DIP-60359N|refseq:XP_006720098.1|refseq:XP_006720100.1|refseq:XP_011534734.1 psi-mi:"MI:0469"(intact) - - comment:alpha/beta tubulin also observed but the accession numbers given in Supp. Table 1 referred to a mouse protein and an obsolete zebrafish protein. As the tubulins are members of a highly conserved family, these proteins have not been remapped.|figure legend:Fig. 1F, Supp. Table 1|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:m1hnsT8xqmD1F301kYJBTbo+Qd09606 intact-crc:727613E645797648|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false tandem tag:?-? - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q8NFJ9 uniprotkb:Q9BXC9 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q96RK4 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - tandem tag:?-? 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q8N3I7 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q8IWZ6 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-1806001|uniprotkb:Q4W5P8|uniprotkb:Q8N581|uniprotkb:Q9NVI4|ensembl:ENSP00000264499 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:bbs7_human(display_long)|uniprotkb:BBS7(gene name)|psi-mi:BBS7(display_short)|uniprotkb:BBS2L1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_060660.2|refseq:NP_789794.1|dip:DIP-46566N|ensembl:ENSG00000138686(gene)|ensembl:ENST00000264499(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|reactome:R-HSA-5620922|go:"GO:0034464"(BBSome) psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:8Czybdr0ILmxLq6yP0gyNPilfzE9606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q15154 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q3SYG4 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q8NFJ9 uniprotkb:Q8TAM2 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-2892638|uniprotkb:Q86SY0|uniprotkb:Q86TV9|uniprotkb:Q86U26|uniprotkb:Q8NDH9|uniprotkb:Q96DG8|uniprotkb:A6NFG2|uniprotkb:B3KWA5|uniprotkb:Q67B97 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:ttc8_human(display_long)|uniprotkb:TTC8(gene name)|psi-mi:TTC8(display_short)|uniprotkb:BBS8(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 8 protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892777|imex:IM-14959-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007411"(axon guidance)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034464"(BBSome)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0048560"(establishment of anatomical structure orientation)|go:"GO:0050893"(sensory processing)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0061326"(renal tubule development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR028796|interpro:IPR019734|refseq:NP_653197.2|refseq:NP_938051.1|refseq:NP_938052.1|reactome:R-HSA-5620922|refseq:NP_001275710.1|refseq:NP_001275711.1|refseq:NP_001275712.1|dip:DIP-60359N|refseq:XP_006720098.1|refseq:XP_006720100.1|refseq:XP_011534734.1 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 2A|comment:sedimentation coefficient = 14 S|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:m1hnsT8xqmD1F301kYJBTbo+Qd09606 intact-crc:60A3D1C19FB4520C|rigid:4fOMdLmLbKcA3Zfk1A5HdLTE5L4 false - - 1 1 psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q3V3N7 uniprotkb:Q9CWF6 intact:EBI-2892836|ensembl:ENSMUSP00000055321 intact:EBI-2892863|ensembl:ENSMUSP00000034206 psi-mi:bbs1_mouse(display_long)|uniprotkb:Bbs1(gene name)|psi-mi:Bbs1(display_short) psi-mi:bbs2_mouse(display_long)|uniprotkb:Bbs2(gene name)|psi-mi:Bbs2(display_short) psi-mi:"MI:0071"(molecular sieving) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892954|imex:IM-14959-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006464(gene)|ensembl:ENSMUST00000053506(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0016358"(dendrite development)|go:"GO:0021591"(ventricular system development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|reactome:R-MMU-5620922|refseq:NP_001028300.1 go:"GO:0044321"(response to leptin)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903441"(protein localization to ciliary membrane)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-MMU-5620922|go:"GO:0043005"(neuron projection)|ensembl:ENSMUSG00000031755(gene)|ensembl:ENSMUST00000034206(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0031514"(motile cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042311"(vasodilation)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|refseq:NP_080392.1|dip:DIP-60351N psi-mi:"MI:0469"(intact) crc64:322E9DD4DD554813 - figure legend:Fig. 2B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2010/07/20 2014/10/16 rogid:utrPbnXQaGf4+UPHfWHVb2RSd7Q10090 rogid:KRmLQ4eWnXQJKSRCOQ7pIDAAIIw10090 intact-crc:2BA307C31D681A03|rigid:VBDZEUxBRjVLhpDHRgHG2RmGu7Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3V3N7 uniprotkb:Q8C1Z7 intact:EBI-2892836|ensembl:ENSMUSP00000055321 intact:EBI-2892887|ensembl:ENSMUSP00000026265|uniprotkb:Q3UYF0|uniprotkb:Q562E1|uniprotkb:Q5EBJ7|uniprotkb:Q8CA57 psi-mi:bbs1_mouse(display_long)|uniprotkb:Bbs1(gene name)|psi-mi:Bbs1(display_short) psi-mi:bbs4_mouse(display_long)|uniprotkb:Bbs4(gene name)|psi-mi:Bbs4(display_short) psi-mi:"MI:0071"(molecular sieving) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892954|imex:IM-14959-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006464(gene)|ensembl:ENSMUST00000053506(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0016358"(dendrite development)|go:"GO:0021591"(ventricular system development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|reactome:R-MMU-5620922|refseq:NP_001028300.1 ensembl:ENSMUSG00000025235(gene)|ensembl:ENSMUST00000026265(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035176"(social behavior)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044321"(response to leptin)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0060324"(face development)|go:"GO:0060613"(fat pad development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902855"(regulation of non-motile cilium assembly)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|reactome:R-MMU-5620922|refseq:NP_780534.1|dip:DIP-60352N psi-mi:"MI:0469"(intact) crc64:322E9DD4DD554813 - figure legend:Fig. 2B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2010/07/20 2014/10/16 rogid:utrPbnXQaGf4+UPHfWHVb2RSd7Q10090 rogid:ypTOupyEotNCkm/1dQKmxoUv0VU10090 intact-crc:2BA307C31D681A03|rigid:VBDZEUxBRjVLhpDHRgHG2RmGu7Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q3V3N7 uniprotkb:Q8K2G4 intact:EBI-2892836|ensembl:ENSMUSP00000055321 intact:EBI-2892924|ensembl:ENSMUSP00000103791|uniprotkb:Q8C7G3|uniprotkb:Q8CH00|uniprotkb:Q9CXC2 psi-mi:bbs1_mouse(display_long)|uniprotkb:Bbs1(gene name)|psi-mi:Bbs1(display_short) psi-mi:bbs7_mouse(display_long)|uniprotkb:Bbs7(gene name)|psi-mi:Bbs7(display_short)|uniprotkb:Bbs2l1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892954|imex:IM-14959-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000006464(gene)|ensembl:ENSMUST00000053506(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001764"(neuron migration)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008104"(protein localization)|go:"GO:0008594"(photoreceptor cell morphogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0016358"(dendrite development)|go:"GO:0021591"(ventricular system development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0031514"(motile cilium)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|reactome:R-MMU-5620922|refseq:NP_001028300.1 ensembl:ENSMUSG00000037325(gene)|ensembl:ENSMUST00000108156(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|mint:Q8K2G4|reactome:R-MMU-5620922|go:"GO:0007224"(smoothened signaling pathway)|refseq:NP_082086.2|dip:DIP-60353N psi-mi:"MI:0469"(intact) crc64:322E9DD4DD554813 - figure legend:Fig. 2B|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-testis)|taxid:10090(Mus musculus testis) - 2010/07/20 2014/10/16 rogid:utrPbnXQaGf4+UPHfWHVb2RSd7Q10090 rogid:7StHJMzhLoqoT+8pRQuNHTdRVW810090 intact-crc:2BA307C31D681A03|rigid:VBDZEUxBRjVLhpDHRgHG2RmGu7Y false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NFJ9 uniprotkb:Q3SYG4 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892968|imex:IM-14959-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:BF7F93176EC21DC8|rigid:v4O059J1ifzUKCNAa0cdUdhWfOA false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BXC9 uniprotkb:Q3SYG4 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892989|imex:IM-14959-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:47A6B0FD9B28BF3E|rigid:1+jN59cJlcrlyO00OlDRWUz2KzE false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3SYG4 uniprotkb:Q8N3I7 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2892997|imex:IM-14959-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:6D40B9A3A8E84078|rigid:TYiegKicFt188nDOwkN78GhbNGg false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3SYG4 uniprotkb:Q8TAM2 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 intact:EBI-2892638|uniprotkb:Q86SY0|uniprotkb:Q86TV9|uniprotkb:Q86U26|uniprotkb:Q8NDH9|uniprotkb:Q96DG8|uniprotkb:A6NFG2|uniprotkb:B3KWA5|uniprotkb:Q67B97 psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:ttc8_human(display_long)|uniprotkb:TTC8(gene name)|psi-mi:TTC8(display_short)|uniprotkb:BBS8(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 8 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893007|imex:IM-14959-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007411"(axon guidance)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034464"(BBSome)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0048560"(establishment of anatomical structure orientation)|go:"GO:0050893"(sensory processing)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0061326"(renal tubule development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR028796|interpro:IPR019734|refseq:NP_653197.2|refseq:NP_938051.1|refseq:NP_938052.1|reactome:R-HSA-5620922|refseq:NP_001275710.1|refseq:NP_001275711.1|refseq:NP_001275712.1|dip:DIP-60359N|refseq:XP_006720098.1|refseq:XP_006720100.1|refseq:XP_011534734.1 psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 rogid:m1hnsT8xqmD1F301kYJBTbo+Qd09606 intact-crc:2711C399D13E4A82|rigid:TNXNk7cJt7HW3nzppJjVeqAjUG4 false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9BXC9 uniprotkb:Q8IWZ6 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 intact:EBI-1806001|uniprotkb:Q4W5P8|uniprotkb:Q8N581|uniprotkb:Q9NVI4|ensembl:ENSP00000264499 psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:bbs7_human(display_long)|uniprotkb:BBS7(gene name)|psi-mi:BBS7(display_short)|uniprotkb:BBS2L1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893015|imex:IM-14959-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N refseq:NP_060660.2|refseq:NP_789794.1|dip:DIP-46566N|ensembl:ENSG00000138686(gene)|ensembl:ENST00000264499(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|reactome:R-HSA-5620922|go:"GO:0034464"(BBSome) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 rogid:8Czybdr0ILmxLq6yP0gyNPilfzE9606 intact-crc:5869AD2BD8DA34F6|rigid:+iU0m/P2fcr+u6c7QCVYJuLtESA false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8IWZ6 uniprotkb:Q9BXC9 intact:EBI-1806001|uniprotkb:Q4W5P8|uniprotkb:Q8N581|uniprotkb:Q9NVI4|ensembl:ENSP00000264499 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 psi-mi:bbs7_human(display_long)|uniprotkb:BBS7(gene name)|psi-mi:BBS7(display_short)|uniprotkb:BBS2L1(gene name synonym)|uniprotkb:BBS2-like protein 1(gene name synonym) psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893023|imex:IM-14959-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060660.2|refseq:NP_789794.1|dip:DIP-46566N|ensembl:ENSG00000138686(gene)|ensembl:ENST00000264499(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046907"(intracellular transport)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051877"(pigment granule aggregation in cell center)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060173"(limb development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1903929"(primary palate development)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR016575(Bardet-Biedl syndrome 7 protein)|interpro:IPR036322|reactome:R-HSA-5620922|go:"GO:0034464"(BBSome) refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:8Czybdr0ILmxLq6yP0gyNPilfzE9606 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 intact-crc:A9E26FC3B556BABC|rigid:+iU0m/P2fcr+u6c7QCVYJuLtESA false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q3SYG4 uniprotkb:Q9BXC9 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 intact:EBI-748297|uniprotkb:Q96CM0|uniprotkb:Q96SN9|ensembl:ENSP00000245157 psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:bbs2_human(display_long)|uniprotkb:BBS2(gene name)|psi-mi:BBS2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893031|imex:IM-14959-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N refseq:NP_114091.3|interpro:IPR016616(Bardet-Biedl syndrome 2 protein)|interpro:IPR029333|interpro:IPR029429|interpro:IPR029430|interpro:IPR036322|reactome:R-HSA-5620922|ensembl:ENSG00000125124(gene)|ensembl:ENST00000245157(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007288"(sperm axoneme assembly)|go:"GO:0007601"(visual perception)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0032402"(melanosome transport)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0031514"(motile cilium)|dip:DIP-46563N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 rogid:yRgKTZdhdvhuMd44Q6Dvo6WN52w9606 intact-crc:15F1C397E4BED2EA|rigid:1+jN59cJlcrlyO00OlDRWUz2KzE false flag tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TAM2 uniprotkb:Q3SYG4 intact:EBI-2892638|uniprotkb:Q86SY0|uniprotkb:Q86TV9|uniprotkb:Q86U26|uniprotkb:Q8NDH9|uniprotkb:Q96DG8|uniprotkb:A6NFG2|uniprotkb:B3KWA5|uniprotkb:Q67B97 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:ttc8_human(display_long)|uniprotkb:TTC8(gene name)|psi-mi:TTC8(display_short)|uniprotkb:BBS8(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 8 protein(gene name synonym) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893039|imex:IM-14959-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001736"(establishment of planar polarity)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007411"(axon guidance)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034464"(BBSome)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0048560"(establishment of anatomical structure orientation)|go:"GO:0050893"(sensory processing)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|go:"GO:0060271"(cilium assembly)|go:"GO:0061326"(renal tubule development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR028796|interpro:IPR019734|refseq:NP_653197.2|refseq:NP_938051.1|refseq:NP_938052.1|reactome:R-HSA-5620922|refseq:NP_001275710.1|refseq:NP_001275711.1|refseq:NP_001275712.1|dip:DIP-60359N|refseq:XP_006720098.1|refseq:XP_006720100.1|refseq:XP_011534734.1 refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:m1hnsT8xqmD1F301kYJBTbo+Qd09606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:112119BF8DEE3429|rigid:TNXNk7cJt7HW3nzppJjVeqAjUG4 false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N3I7 uniprotkb:Q3SYG4 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893047|imex:IM-14959-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:A7C34A38F741D381|rigid:TYiegKicFt188nDOwkN78GhbNGg false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NFJ9 uniprotkb:Q3SYG4 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-2826852|uniprotkb:Q8N570|uniprotkb:P78514|uniprotkb:Q9Y6A0|uniprotkb:Q9Y699|uniprotkb:Q99854|uniprotkb:Q7KYS7|uniprotkb:Q99844|uniprotkb:Q7KYS6|ensembl:ENSP00000242067|uniprotkb:E9PDC9 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:pthb1_human(display_long)|uniprotkb:PTHB1(gene name synonym)|uniprotkb:Parathyroid hormone-responsive B1 gene protein(gene name synonym)|uniprotkb:Bardet-Biedl syndrome 9 protein(gene name synonym)|uniprotkb:BBS9(gene name)|psi-mi:BBS9(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893055|imex:IM-14959-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_001028776.1|refseq:NP_001028777.1|refseq:NP_055266.2|refseq:NP_940820.1|refseq:NP_001334965.1|ensembl:ENSG00000122507(gene)|ensembl:ENST00000242067(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR026511|interpro:IPR028073|interpro:IPR028074|rcsb pdb:4YD8|rcsb pdb:6XT9|reactome:R-HSA-5620922|dip:DIP-60358N psi-mi:"MI:0469"(intact) - - figure legend:Supp.Fig. 3|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:eKl4Nncm7CuSPi1GKrGhJ5IJsFY9606 intact-crc:75F31A0F690FA875|rigid:v4O059J1ifzUKCNAa0cdUdhWfOA false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96QF0-1 uniprotkb:Q8NFJ9 intact:EBI-747860|ensembl:ENSP00000447300 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 psi-mi:q96qf0-1(display_long)|uniprotkb:alpha2(isoform synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RABIN8(gene name synonym) psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893146|imex:IM-14959-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-747844(rab3i_human)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6B, Supp. Fig. 9|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 intact-crc:CB162DAEE1C2CDF3|rigid:5rdmLLuk8gsz5o6YcCC0sMAnJ98 false necessary binding region:297-460|green fluorescent protein tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NFJ9 uniprotkb:Q96QF0-1 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 intact:EBI-747860|ensembl:ENSP00000447300 psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:q96qf0-1(display_long)|uniprotkb:alpha2(isoform synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RABIN8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893162|imex:IM-14959-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 intact:EBI-747844(rab3i_human)|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 9|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/07/20 2014/10/16 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 intact-crc:54D7A8C1A463E1FD|rigid:5rdmLLuk8gsz5o6YcCC0sMAnJ98 false myc tag:?-? green fluorescent protein tag:?-?|necessary binding region:297-460 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96RK4 uniprotkb:Q15154 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893069|imex:IM-14959-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3C|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 intact-crc:23DCA8E7056AAF00|rigid:4HKDggtYq9GVRsHBeXdJMITkymw false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96RK4 uniprotkb:Q8NFJ9 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 intact:EBI-1805484|uniprotkb:Q32MN0|uniprotkb:Q96SN4|uniprotkb:Q32MM9|ensembl:ENSP00000317469 psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:bbs1_human(display_long)|uniprotkb:BBS1(gene name)|psi-mi:BBS1(display_short)|uniprotkb:BBS2L2(gene name synonym)|uniprotkb:BBS2-like protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893069|imex:IM-14959-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 refseq:NP_078925.3|dip:DIP-46564N|ensembl:ENSG00000174483(gene)|ensembl:ENST00000318312(transcript)|go:"GO:0005113"(patched binding)|go:"GO:0005119"(smoothened binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR028784|interpro:IPR032728|rcsb pdb:6XT9|reactome:R-HSA-5620922 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 3C|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2018/04/06 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 rogid:llE02FVGJZcnFUY1VgTFvCtlvtM9606 intact-crc:23DCA8E7056AAF00|rigid:4HKDggtYq9GVRsHBeXdJMITkymw false tandem tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QF0 uniprotkb:Q96RK4 intact:EBI-747844|uniprotkb:Q6PCE4|uniprotkb:Q96A24|uniprotkb:Q96QE6|uniprotkb:Q96QE7|uniprotkb:Q96QE8|uniprotkb:Q96QE9|uniprotkb:Q96QF1|uniprotkb:Q9H673|uniprotkb:B7WPJ6|ensembl:ENSP00000447300 intact:EBI-1805814|uniprotkb:Q53DZ5|uniprotkb:Q8NHU9|uniprotkb:Q96H45|uniprotkb:B4E178|ensembl:ENSP00000268057 psi-mi:rab3i_human(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:RAB3IP(gene name)|psi-mi:RAB3IP(display_short)|uniprotkb:RABIN8(gene name synonym) psi-mi:bbs4_human(display_long)|uniprotkb:BBS4(gene name)|psi-mi:BBS4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2893140|imex:IM-14959-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001265331.1|refseq:NP_001019818.1|refseq:NP_071901.2|refseq:NP_783322.1|refseq:NP_783323.1|refseq:NP_783324.1|ensembl:ENST00000247833|ensembl:ENSP00000247833|ensembl:ENST00000362025|ensembl:ENSP00000355381|ensembl:ENST00000378815|ensembl:ENSP00000368092|ensembl:ENST00000417413|ensembl:ENSP00000436304|ensembl:ENSP00000419216|ensembl:ENSP00000447300|ensembl:ENST00000551641|ensembl:ENSP00000448773|ensembl:ENST00000552199|ensembl:ENSP00000448944|ensembl:ENST00000553099|ensembl:ENSP00000448027|ensembl:ENST00000483530|refseq:XP_016874262.1|refseq:XP_016874265.1|refseq:XP_016874266.1|ensembl:ENSG00000127328(gene)|ensembl:ENST00000550536(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|go:"GO:0097711"(ciliary basal body-plasma membrane docking)|interpro:IPR009449(GDPGTP exchange factor Sec2p)|interpro:IPR040351|mint:Q96QF0|rcsb pdb:4LHX|rcsb pdb:4LHY|rcsb pdb:4LHZ|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:6F6P|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-5620922|reactome:R-HSA-8876198|dip:DIP-41703N refseq:XP_016877940.1|refseq:XP_016877941.1|refseq:XP_016877942.1|refseq:XP_016877943.1|refseq:XP_011520150.1|refseq:XP_011520151.1|refseq:NP_149017.2|refseq:NP_001307594.1|refseq:NP_001239607.1|dip:DIP-46540N|ensembl:ENSG00000140463(gene)|ensembl:ENST00000268057(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001947"(heart looping)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007286"(spermatid development)|go:"GO:0007601"(visual perception)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0015031"(protein transport)|go:"GO:0016358"(dendrite development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030534"(adult behavior)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031514"(motile cilium)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034452"(dynactin binding)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0034464"(BBSome)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0038108"(negative regulation of appetite by leptin-mediated signaling pathway)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050893"(sensory processing)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR028786|rcsb pdb:6XT9|reactome:R-HSA-5620922 psi-mi:"MI:0469"(intact) - - figure legend:Fig. 6A|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-rpe)|taxid:9606(Human retinal pigment epithelium cell line) - 2010/07/20 2014/10/16 rogid:F/h4kufeBER1JEgPkcwIPTar/9o9606 rogid:3qsiARZJocEgNJjKuItz0Pv6mTA9606 intact-crc:4386782B82410CF5|rigid:h5npTPXpQJ28FiRw/Yr2DRaZavs false - tandem tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) chebi:"CHEBI:17283" uniprotkb:Q8N3I7 intact:EBI-1257113 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893083|imex:IM-14959-18 author score:Strong - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:6FF2332180A7C8A8 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:17526" uniprotkb:Q8N3I7 intact:EBI-2465282 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893092|imex:IM-14959-19 author score:Weak - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:441A9C0926F80F97 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16500" uniprotkb:Q8N3I7 intact:EBI-1257117 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:pi5p(display_short)|psi-mi:"CHEBI:16500"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893099|imex:IM-14959-20 author score:Weak - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:0610C73D25D33B95 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16152" uniprotkb:Q8N3I7 intact:EBI-2296297 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:1-phosphatidyl-1d-myo-inositol 3,4-bisphosphate(display_short)|psi-mi:"CHEBI:16152"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893106|imex:IM-14959-21 author score:Weak - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:810CE89006036949 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16851" uniprotkb:Q8N3I7 intact:EBI-1257121 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate(display_short)|psi-mi:"CHEBI:16851"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893113|imex:IM-14959-22 author score:Weak - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:40D7D7432D3CBA62 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16337" uniprotkb:Q8N3I7 intact:EBI-1263288 intact:EBI-2892592|intact:EBI-28972415|uniprotkb:Q6PKN0|uniprotkb:D3DPC3|ensembl:ENSP00000295240 psi-mi:phosphatidic acids(display_short)|psi-mi:"CHEBI:16337"(display_long) psi-mi:bbs5_human(display_long)|uniprotkb:BBS5(gene name)|psi-mi:BBS5(display_short) psi-mi:"MI:0049"(filter binding) Nachury et al. (2007) imex:IM-14959|pubmed:17574030 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2893120|imex:IM-14959-23 author score:Strong - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSP00000295240|ensembl:ENST00000392663|ensembl:ENSP00000376431|refseq:NP_689597.1|dip:DIP-60357N|go:"GO:0034464"(BBSome)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0046907"(intracellular transport)|go:"GO:0050896"(response to stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR006606(Protein of unknown function DUF1448)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014003(Protein of unknown function DM16)|interpro:IPR030804|rcsb pdb:6XTB|reactome:R-HSA-5620922|ensembl:ENSG00000163093(gene)|ensembl:ENST00000295240(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0034451"(centriolar satellite) - - - figure legend:Fig. 5D|dataset:Diabetes - Interactions investigated in the context of Diabetes|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/20 2014/10/16 - rogid:c0TpyFlyIP03JBq2ONTR3YL1bf09606 intact-crc:0D54962CEAEDBCB2 false - glutathione s tranferase tag:?-?|sufficient binding region:1-149 - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)