#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O46385 uniprotkb:Q45KY7 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-8518012|intact:MINT-7901059 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:q45ky7_bovin(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) interpro:IPR000980(SH2 motif)|mint:Q45KY7|interpro:IPR036860|go:"GO:0016301"(kinase activity)|mint:MINT-7902310(identity)|uniprotkb:Q45KY7(original identifier) - comment:mint comment:mint figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:2JxZte8yVP1skOK4IKtmQTgm4AE9913 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:A6QLR4 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-8517993|intact:MINT-7901036|ensembl:ENSBTAP00000035143 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:flot2_bovin(display_long)|uniprotkb:FLOT2(gene name)|psi-mi:FLOT2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) refseq:NP_001030543.2|ensembl:ENSBTAG00000010073(gene)|ensembl:ENSBTAT00000035265(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0016600"(flotillin complex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045661"(regulation of myoblast differentiation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR031905|interpro:IPR036013|mint:A6QLR4|mint:MINT-7902304(identity)|uniprotkb:A6QLR4(original identifier) - comment:mint comment:mint figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:8wKZOYTuHea0FTC/hVtoLojCYqI9913 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:Q5SUA5 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-777663|ensembl:ENSMUSP00000003459|uniprotkb:Q8BJ17|uniprotkb:Q8BJ65|uniprotkb:Q8R019|uniprotkb:Q91ZI1|uniprotkb:Q8BIT8 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:myo1g_mouse(display_long)|uniprotkb:Myo1g(gene name)|psi-mi:Myo1g(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) ensembl:ENSMUSG00000020437(gene)|ensembl:ENSMUST00000003459(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002456"(T cell mediated immunity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_848534.2|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031982"(vesicle)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0071976"(cell gliding)|go:"GO:0120117"(T cell meandering migration)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:Q5SUA5|mint:MINT-7902316(identity)|uniprotkb:Q5SUA5(original identifier) - comment:mint - figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:mIzhibZW73U3Fz9pkzll2qGaTPs10090 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:P60712 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-5282124|uniprotkb:A5D961|uniprotkb:A5PKA1|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3SZD2|uniprotkb:Q64316|uniprotkb:Q8MIJ0|ensembl:ENSBTAP00000036739 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:actb_bovin(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) refseq:NP_776404.2|dip:DIP-57682N|ensembl:ENSBTAG00000026199(gene)|ensembl:ENSBTAT00000036888(transcript)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60712|rcsb pdb:1HLU|rcsb pdb:2OAN|rcsb pdb:3U4L|rcsb pdb:3UB5|rcsb pdb:2BTF|mint:MINT-7902301(identity)|uniprotkb:P60712(original identifier) - comment:mint - figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9913 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:Q13813 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N|mint:MINT-7902319(identity)|uniprotkb:Q13813(original identifier) - comment:mint - figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:P04899 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899|mint:MINT-7902307(identity)|uniprotkb:Q6B6N3(original identifier) - comment:mint - figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:P35579 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8518008|mint:MINT-7902300 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902322(identity)|uniprotkb:O46385(original identifier) refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N|mint:MINT-7902313(identity)|uniprotkb:P35579(original identifier) - comment:mint - figure legend:f5|comment:mint|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 intact-crc:44B7FB0EF01931E2|rigid:ozTEK+ZhgB4VbSIxlZZd9hjJcyg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O46385 uniprotkb:P04899 intact:EBI-6995105|intact:MINT-7898149 intact:EBI-353997|uniprotkb:Q8IZ71|intact:EBI-2563889|uniprotkb:B4DYA0|intact:EBI-4404691|uniprotkb:Q6B6N3|uniprotkb:B3KTZ0|uniprotkb:B4E2X5|ensembl:ENSP00000312999 psi-mi:svil_bovin(display_long)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym) psi-mi:gnai2_human(display_long)|uniprotkb:GNAI2(gene name)|psi-mi:GNAI2(display_short)|uniprotkb:GNAI2B(gene name synonym)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nebl et al. (2002) mint:MINT-7902293|pubmed:12202484|doi:10.1074/jbc.M205386200 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8518062|mint:MINT-7902328 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR007123(Gelsolin region)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|refseq:NP_776615.1|interpro:IPR015628(Supervillin)|interpro:IPR029006|mint:O46385|interpro:IPR036886|mint:MINT-7902329(identity)|uniprotkb:O46385(original identifier) refseq:NP_002061.1|refseq:NP_001269546.1|refseq:NP_001269549.1|refseq:NP_001269547.1|refseq:NP_001269548.1|refseq:NP_001159897.1|dip:DIP-602N|ensembl:ENSG00000114353(gene)|ensembl:ENST00000313601(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:0030425"(dendrite)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rcsb pdb:6D9H|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|mint:P04899|mint:MINT-7902332(identity)|uniprotkb:Q6B6N3(original identifier) - comment:mint - comment:mint|figure legend:f7d|partial coverage:partial coverage taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") - 2010/06/09 2014/10/16 rogid:HIX/Fqj0ygV+ubbpwughIV0COYY9913 rogid:Mi3PAXudkdPb375bOi7luNAmUaU9606 intact-crc:BA6B4AC344ACFA8C|rigid:6NQaIJDgz8c/nKE9fvJl6laodtg false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)