#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32908 uniprotkb:Q9UQE7 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653109|imex:IM-18952-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - crc64:B504017AA0ECCA8C - figure legend:Fig. 2B|comment:Molecular weight of approx 260 kDa for the Smc1/His6Smc3 complex was calculated from the Stokes radius and sedimentation velocity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:83D13C775C9E7725|rigid:QwuVEEFy2WfexNRKF34PjpD98YA false - his tag:?-? 1 1 psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P32908 uniprotkb:Q9UQE7 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653128|imex:IM-18952-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - crc64:B504017AA0ECCA8C - figure legend:Fig. 2B|comment:Molecular weight of approx 260 kDa for the Smc1/His6Smc3 complex was calculated from the Stokes radius and sedimentation velocity.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:63525DD605D3D34E|rigid:QwuVEEFy2WfexNRKF34PjpD98YA false - his tag:?-? 1 1 psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q9UQE7 uniprotkb:P32908 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0040"(electron microscopy) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653151|imex:IM-18952-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - - crc64:B504017AA0ECCA8C figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:D2B5B23699541F8E|rigid:QwuVEEFy2WfexNRKF34PjpD98YA false his tag:?-? - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UQE7 intact:EBI-2653205 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 - psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:smc3-hinge1_yeast(display_short)|psi-mi:EBI-2653205(display_long) psi-mi:"MI:0040"(electron microscopy) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2653231|imex:IM-18952-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:9Um92TUz9MWfaXcLfEQxAHXdZhI4932 intact-crc:D187AB7DC45B38F3|rigid:hB+u4rkrmQi75Qc95Pb7sxmyPwc false ha tag:?-? his tag:?-? 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32908 uniprotkb:Q9UQE7 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653165|imex:IM-18952-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - crc64:B504017AA0ECCA8C - figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 intact-crc:50F42A96049894F5|rigid:QwuVEEFy2WfexNRKF34PjpD98YA false necessary binding region:500-696(IPR010935) his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UQE7 intact:EBI-2653205 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 - psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:smc3-hinge1_yeast(display_short)|psi-mi:EBI-2653205(display_long) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653209|imex:IM-18952-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rogid:9Um92TUz9MWfaXcLfEQxAHXdZhI4932 intact-crc:5C283BEC76663A22|rigid:hB+u4rkrmQi75Qc95Pb7sxmyPwc false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2653205 intact:EBI-2653201 - - psi-mi:smc3-hinge1_yeast(display_short)|psi-mi:EBI-2653205(display_long) psi-mi:smc1-hinge3_yeast(display_short)|psi-mi:EBI-2653201(display_long) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653216|imex:IM-18952-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - - - no-uniprot-update:An amino acid sequence which is not represented in UniProt no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:9Um92TUz9MWfaXcLfEQxAHXdZhI4932 rogid:s9hdHLdcwpF7her822Mpd6IJAxA4932 intact-crc:DEC96858836CCB4F|rigid:manLy3QNPN1Lr/neXIZdQ5A90F4 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12158 uniprotkb:P32908 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653286|imex:IM-18952-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:EB6C7CA33BAC208F crc64:B504017AA0ECCA8C figure legend:Figs. 4A, 4C, 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:46DCCD7F63BFDF4F|rigid:oiHuAmHG3ObvmTb/Wg11aSSmFjo false his tag:?-? necessary binding region:1-170 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2653205 uniprotkb:Q12158 - intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3-hinge1_yeast(display_short)|psi-mi:EBI-2653205(display_long) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653396|imex:IM-18952-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - no-uniprot-update:An amino acid sequence which is not represented in UniProt crc64:EB6C7CA33BAC208F figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:9Um92TUz9MWfaXcLfEQxAHXdZhI4932 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:76CF4ED5B243394A|rigid:V/uM4rvK/INGGus7eFFkhgUsot8 false his tag:?-? flag tag:c-c|sufficient binding region:269-566(IPR006910) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-2653205 uniprotkb:P32908 - intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3-hinge1_yeast(display_short)|psi-mi:EBI-2653205(display_long) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653396|imex:IM-18952-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) - refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - no-uniprot-update:An amino acid sequence which is not represented in UniProt crc64:B504017AA0ECCA8C figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:9Um92TUz9MWfaXcLfEQxAHXdZhI4932 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:76CF4ED5B243394A|rigid:V/uM4rvK/INGGus7eFFkhgUsot8 false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653250|imex:IM-18952-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:647A1E486B90AF7D|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false ha tag:?-?|necessary binding region:484-684(IPR010935) - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12158 uniprotkb:P47037 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653335|imex:IM-18952-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:EB6C7CA33BAC208F crc64:B152D88F7780341F figure legend:Fig. 4E|comment:N- and C-terminal globular domains of Smc3 are fused by a short linker region.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:FF9145AB62086263|rigid:PtoIjBMY5gYc5XB5W8za/YYKOWw false his tag:?-? ha tag:?-?|sufficient binding region:1-170,1041-1230 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 intact:EBI-2653201 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C - psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1-hinge3_yeast(display_short)|psi-mi:EBI-2653201(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653415|imex:IM-18952-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - - crc64:B152D88F7780341F no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:s9hdHLdcwpF7her822Mpd6IJAxA4932 intact-crc:F610B41850D19C8A|rigid:a7IOLuGXmNMLIbs2JiSYNczkfso false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:Q12158 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653415|imex:IM-18952-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B152D88F7780341F crc64:EB6C7CA33BAC208F figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:F610B41850D19C8A|rigid:a7IOLuGXmNMLIbs2JiSYNczkfso false ha tag:?-? his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12158 uniprotkb:P47037 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653428|imex:IM-18952-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:EB6C7CA33BAC208F crc64:B152D88F7780341F figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:B54CB1BAA5019529|rigid:PtoIjBMY5gYc5XB5W8za/YYKOWw false his tag:?-?|sufficient binding region:1-180 ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:Q12158 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653542|imex:IM-18952-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B152D88F7780341F crc64:EB6C7CA33BAC208F figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:A263A36DA4493330|rigid:x+Su/tmOG+KBiUPRdUw1tqVoaGE false ha tag:?-? his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:P40541 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16667|uniprotkb:Q02511|ensemblfungi:YIL026C|uniprotkb:D6VVQ4 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc3_yeast(display_long)|uniprotkb:YIL026C(locus name)|uniprotkb:IRR1(gene name)|psi-mi:IRR1(display_short)|uniprotkb:SCC3(gene name synonym)|uniprotkb:Irregular cell behavior protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653542|imex:IM-18952-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 ensemblfungi:YIL026C(gene)|ensemblfungi:YIL026C_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|rcsb pdb:4UVJ|rcsb pdb:6H8Q|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|refseq:NP_012238.1|sgd:S000001288|dip:DIP-5640N|mint:P40541 - crc64:B152D88F7780341F crc64:89688EA09485AC28 figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:HeIbL+2Bebii0Vtuc42xsR9XAl4559292 intact-crc:A263A36DA4493330|rigid:x+Su/tmOG+KBiUPRdUw1tqVoaGE false ha tag:?-? myc tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653542|imex:IM-18952-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:Fig. 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:A263A36DA4493330|rigid:x+Su/tmOG+KBiUPRdUw1tqVoaGE false ha tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P32908 uniprotkb:P47037 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2653274|imex:IM-18952-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:B504017AA0ECCA8C crc64:B152D88F7780341F figure legend:Fig. 3D|kinetics:Affinity constant = 2E8/M-1,|kinetic_conditions:pH 5.0|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:0A35AEFF60D0A010|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false - ha tag:?-?|necessary binding region:484-684(IPR010935) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47037 uniprotkb:Q12158 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653303|imex:IM-18952-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B152D88F7780341F crc64:EB6C7CA33BAC208F figure legend:Figs. 4A, 4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:38036DC62D0AFBB8|rigid:PtoIjBMY5gYc5XB5W8za/YYKOWw false ha tag:?-?|necessary binding region:1-171 his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P40541 uniprotkb:Q12158 intact:EBI-16667|uniprotkb:Q02511|ensemblfungi:YIL026C|uniprotkb:D6VVQ4 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:scc3_yeast(display_long)|uniprotkb:YIL026C(locus name)|uniprotkb:IRR1(gene name)|psi-mi:IRR1(display_short)|uniprotkb:SCC3(gene name synonym)|uniprotkb:Irregular cell behavior protein 1(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653517|imex:IM-18952-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL026C(gene)|ensemblfungi:YIL026C_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|rcsb pdb:4UVJ|rcsb pdb:6H8Q|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|refseq:NP_012238.1|sgd:S000001288|dip:DIP-5640N|mint:P40541 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:89688EA09485AC28 crc64:EB6C7CA33BAC208F figure legend:Figs. 7A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:HeIbL+2Bebii0Vtuc42xsR9XAl4559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:6C6FF565BB013785|rigid:IhPLmctZBm/FSB5Lp/A8GMbfnLw false myc tag:?-? his tag:?-?|sufficient binding region:269-566 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12158 uniprotkb:P47037 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653324|imex:IM-18952-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:EB6C7CA33BAC208F crc64:B152D88F7780341F figure legend:Figs. 4B|comment:Contaminating HSP70 was identified by mass spectrometry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:DBFDCD0F734057AC|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false his tag:?-? ha tag:?-? - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q12158 uniprotkb:P32908 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0096"(pull down) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653324|imex:IM-18952-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:EB6C7CA33BAC208F crc64:B504017AA0ECCA8C figure legend:Figs. 4B|comment:Contaminating HSP70 was identified by mass spectrometry.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:DBFDCD0F734057AC|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false his tag:?-? - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:P32908 uniprotkb:Q12158 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653359|imex:IM-18952-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B504017AA0ECCA8C crc64:EB6C7CA33BAC208F figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:5EF126F1529271E6|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-?|sufficient binding region:175-1063 his tag:?-?|sufficient binding region:1-180(IPR006910) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32908 uniprotkb:P47037 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653359|imex:IM-18952-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:B504017AA0ECCA8C crc64:B152D88F7780341F figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:5EF126F1529271E6|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-?|sufficient binding region:175-1063 his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32908 uniprotkb:P47037 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653377|imex:IM-18952-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:B504017AA0ECCA8C crc64:B152D88F7780341F figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:A0E971062081BAC0|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-? his tag:c-c|sufficient binding region:172-1042 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32908 uniprotkb:Q12158 intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653377|imex:IM-18952-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B504017AA0ECCA8C crc64:EB6C7CA33BAC208F figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:A0E971062081BAC0|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-? his tag:?-?|sufficient binding region:269-566(IPR006910) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653465|imex:IM-18952-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:3FD25E1DD429A3CF|rigid:zO9cPHibKJqQndNlvxW0a0ImZNA false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12158 uniprotkb:P47037 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653477|imex:IM-18952-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:EB6C7CA33BAC208F crc64:B152D88F7780341F figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:260FFC49FA39C575|rigid:PtoIjBMY5gYc5XB5W8za/YYKOWw false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:P47037 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653488|imex:IM-18952-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 - crc64:B152D88F7780341F crc64:B152D88F7780341F figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 intact-crc:3C652AF3A5C97288|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:Q12158 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653488|imex:IM-18952-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:B152D88F7780341F crc64:EB6C7CA33BAC208F figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:3C652AF3A5C97288|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-? his tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47037 uniprotkb:P32908 intact:EBI-17423|uniprotkb:D6VWA9|ensemblfungi:YJL074C intact:EBI-17402|uniprotkb:D6VTM2|ensemblfungi:YFL008W psi-mi:smc3_yeast(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:YJL074C(locus name)|uniprotkb:J1049(orf name)|uniprotkb:DA-box protein SMC3(gene name synonym) psi-mi:smc1_yeast(display_long)|uniprotkb:YFL008W(locus name)|uniprotkb:SMC1(gene name)|psi-mi:SMC1(display_short)|uniprotkb:CHL10(gene name synonym)|uniprotkb:DA-box protein SMC1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653488|imex:IM-18952-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012461.1|sgd:S000003610|ensemblfungi:YJL074C(gene)|ensemblfungi:YJL074C_mRNA(transcript)|go:"GO:0005524"(ATP binding)|reactome:R-SCE-3108214|go:"GO:0005634"(nucleus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|rcsb pdb:4UX3|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|dip:DIP-2991N|mint:P47037 refseq:NP_116647.1|sgd:S000001886|ensemblfungi:YFL008W(gene)|ensemblfungi:YFL008W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000217"(DNA secondary structure binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051301"(cell division)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR036277|rcsb pdb:1W1W|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|mint:P32908|dip:DIP-2982N - crc64:B152D88F7780341F crc64:B504017AA0ECCA8C figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:7ToxQ9e0FAQv7dhJ0+s4v6KUeyw559292 rogid:reZC2J2XVNMN011NY2Ot1mKFsx0559292 intact-crc:3C652AF3A5C97288|rigid:zjxd7X4VD9aEBBEBkHKuuzHC5cg false ha tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P40541 uniprotkb:Q12158 intact:EBI-16667|uniprotkb:Q02511|ensemblfungi:YIL026C|uniprotkb:D6VVQ4 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:scc3_yeast(display_long)|uniprotkb:YIL026C(locus name)|uniprotkb:IRR1(gene name)|psi-mi:IRR1(display_short)|uniprotkb:SCC3(gene name synonym)|uniprotkb:Irregular cell behavior protein 1(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653555|imex:IM-18952-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL026C(gene)|ensemblfungi:YIL026C_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|rcsb pdb:4UVJ|rcsb pdb:6H8Q|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|refseq:NP_012238.1|sgd:S000001288|dip:DIP-5640N|mint:P40541 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:89688EA09485AC28 crc64:EB6C7CA33BAC208F figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:HeIbL+2Bebii0Vtuc42xsR9XAl4559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:6A1DC2E7E113A17B|rigid:IhPLmctZBm/FSB5Lp/A8GMbfnLw false ha tag:c-c myc tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P40541 uniprotkb:Q12158 intact:EBI-16667|uniprotkb:Q02511|ensemblfungi:YIL026C|uniprotkb:D6VVQ4 intact:EBI-16655|uniprotkb:Q05325|ensemblfungi:YDL003W|uniprotkb:D6VRY5 psi-mi:scc3_yeast(display_long)|uniprotkb:YIL026C(locus name)|uniprotkb:IRR1(gene name)|psi-mi:IRR1(display_short)|uniprotkb:SCC3(gene name synonym)|uniprotkb:Irregular cell behavior protein 1(gene name synonym) psi-mi:scc1_yeast(display_long)|uniprotkb:MCD1(gene name)|psi-mi:MCD1(display_short)|uniprotkb:PDS3(gene name synonym)|uniprotkb:RHC21(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDL003W(locus name)|uniprotkb:YD8119.04(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2653564|imex:IM-18952-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL026C(gene)|ensemblfungi:YIL026C_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006473"(protein acetylation)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0051301"(cell division)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|rcsb pdb:4UVJ|rcsb pdb:6H8Q|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|refseq:NP_012238.1|sgd:S000001288|dip:DIP-5640N|mint:P40541 interpro:IPR039781|rcsb pdb:1W1W|rcsb pdb:4UX3|rcsb pdb:5FRP|rcsb pdb:5FRS|rcsb pdb:6H8Q|rcsb pdb:6QPQ|rcsb pdb:6QPW|rcsb pdb:6ZZ6|reactome:R-SCE-2468052|reactome:R-SCE-2500257|reactome:R-SCE-3108214|ensemblfungi:YDL003W(gene)|ensemblfungi:YDL003W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051301"(cell division)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|refseq:NP_010281.1|sgd:S000002161|dip:DIP-5812N|mint:Q12158 - crc64:89688EA09485AC28 crc64:EB6C7CA33BAC208F figure legend:Fig. 7c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells) - 2010/05/04 2014/10/16 rogid:HeIbL+2Bebii0Vtuc42xsR9XAl4559292 rogid:JAtNEvX2XIIyw8F0zguKi0y6F1Q559292 intact-crc:FF324DCEF38A0B87|rigid:IhPLmctZBm/FSB5Lp/A8GMbfnLw false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9X0R4 uniprotkb:Q9X0R4 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:"MI:0114"(x-ray crystallography) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2653617|wwpdb:1gxj|imex:IM-18952-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 - - - figure legend:Fig. 1, Table 1|3d-resolution:2A|3d-r-factors:"R-factor: 22.62%, Free R-factor: 26.53%"|assembly:Homodimeric|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/04 2014/10/16 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 intact-crc:C40856909CAA2527|rigid:rwgqt8zCssUMic1YSL4MFxuXUB4 false sufficient binding region:485-670(IPR010935) sufficient binding region:485-670(IPR010935) 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9X0R4 uniprotkb:Q9X0R4 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:"MI:0114"(x-ray crystallography) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2878654|wwpdb:1gxk|imex:IM-18952-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 - - - figure legend:Fig. 1, Table 1|3d-resolution:3A|3d-r-factors:"R-factor: 25.3%, Free R-factor: 29.8%"|assembly:Homodimeric|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/04 2014/10/16 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 intact-crc:8DF5AF936F2472AA|rigid:rwgqt8zCssUMic1YSL4MFxuXUB4 false sufficient binding region:485-670(IPR010935) sufficient binding region:485-670(IPR010935) 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9X0R4 uniprotkb:Q9X0R4 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 intact:EBI-2653600|uniprotkb:G4FEG4|ensemblbacteria:AAD36257 psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:q9x0r4_thema(display_long)|uniprotkb:smc(gene name)|psi-mi:smc(display_short)|uniprotkb:TM_1182(locus name) psi-mi:"MI:0114"(x-ray crystallography) Haering et al. (2002) pubmed:11983169|imex:IM-18952 taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") taxid:243274(thema)|taxid:243274("Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2878664|wwpdb:1gxl|imex:IM-18952-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 refseq:NP_228987.1|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR024704|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR011890(Chromosome segregation protein SMC)|rcsb pdb:1E69|rcsb pdb:1GXJ|rcsb pdb:1GXK|rcsb pdb:1GXL|ensemblbacteria:AAD36257(transcript)|ensemblbacteria:TM_1182(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042802"(identical protein binding)|interpro:IPR027417|refseq:WP_004080167.1|interpro:IPR036277 - - - figure legend:Fig. 1, Table 1|3d-resolution:3A|3d-r-factors:"R-factor: 25.24%, Free R-factor: 30.1%"|assembly:Homodimeric|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/05/04 2014/10/16 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 rogid:MZf42VRIJmHfUIP8aMHrPDDAGrY243274 intact-crc:227B7B92D0A4C9BB|rigid:rwgqt8zCssUMic1YSL4MFxuXUB4 false sufficient binding region:473-685(IPR010935) sufficient binding region:473-685(IPR010935) 4 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)