#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P39008 uniprotkb:P53829 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:F3CAF97106A65933 crc64:F3DBABE6AD3C7F3C figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:Q12514 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 - crc64:F3CAF97106A65933 crc64:073137119B3E92BC figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:P31384 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C - crc64:F3CAF97106A65933 crc64:5CDB2E8FEDDBEF6F figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:P34909 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 - crc64:F3CAF97106A65933 crc64:8847084BD9BF48B7 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:P53280 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:F3CAF97106A65933 crc64:BF3542816CC78490 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:P06100 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 - crc64:F3CAF97106A65933 crc64:7D0B69657F791371 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P39008 uniprotkb:P25655 intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564751|imex:IM-19283-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:F3CAF97106A65933 crc64:5B2AE15BCF95E009 figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:CD714A6E355C99F3|rigid:zBHqV9CnQ3gKHGnIQo2/3snh6Wg false his tag:c-c - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P31384 uniprotkb:P53280 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564769|imex:IM-19283-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:5CDB2E8FEDDBEF6F crc64:BF3542816CC78490 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:FAC7BA2BB61C55A9|rigid:dKDqyCWvVYB4Ez+CINZXoJUCV28 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P34909 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564769|imex:IM-19283-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 - crc64:5CDB2E8FEDDBEF6F crc64:8847084BD9BF48B7 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:FAC7BA2BB61C55A9|rigid:dKDqyCWvVYB4Ez+CINZXoJUCV28 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:Q12514 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564769|imex:IM-19283-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 - crc64:5CDB2E8FEDDBEF6F crc64:073137119B3E92BC figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:FAC7BA2BB61C55A9|rigid:dKDqyCWvVYB4Ez+CINZXoJUCV28 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P53829 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564769|imex:IM-19283-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:5CDB2E8FEDDBEF6F crc64:F3DBABE6AD3C7F3C figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:FAC7BA2BB61C55A9|rigid:dKDqyCWvVYB4Ez+CINZXoJUCV28 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P34909 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 - crc64:F3DBABE6AD3C7F3C crc64:8847084BD9BF48B7 figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P39008 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N - crc64:F3DBABE6AD3C7F3C crc64:F3CAF97106A65933 figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P31384 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C - crc64:F3DBABE6AD3C7F3C crc64:5CDB2E8FEDDBEF6F figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P53280 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:F3DBABE6AD3C7F3C crc64:BF3542816CC78490 figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:Q12514 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 - crc64:F3DBABE6AD3C7F3C crc64:073137119B3E92BC figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P25655 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:F3DBABE6AD3C7F3C crc64:5B2AE15BCF95E009 figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P06100 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12153|uniprotkb:D6VRI6|ensemblfungi:YDL165W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not2_yeast(display_long)|uniprotkb:CDC36(gene name)|psi-mi:CDC36(display_short)|uniprotkb:DNA19(gene name synonym)|uniprotkb:NOT2(gene name synonym)|uniprotkb:YDL165W(locus name)|uniprotkb:cell division cycle protein 36(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YDL165W(gene)|ensemblfungi:YDL165W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|refseq:NP_010116.1|sgd:S000002324|dip:DIP-590N|mint:P06100 - crc64:F3DBABE6AD3C7F3C crc64:7D0B69657F791371 figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:bOgpnRcqWbxkhHJg140qzPxIBJQ559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P06102 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564777|imex:IM-19283-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 - crc64:F3DBABE6AD3C7F3C crc64:69B76694FCC6846F figure legend:Fig. 2b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:BF90E61F14C83E03|rigid:1wniRwWr/vO9gt2PPFFCEZgzjKQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P53280 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564804|imex:IM-19283-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:5CDB2E8FEDDBEF6F crc64:BF3542816CC78490 figure legend:Fig. 4A, Fig. 5|comment:caf40 and caf130 deletions do not affect the formation of the CCR4-NOT complex.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:874BED882455E53A|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P25655 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564804|imex:IM-19283-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:5CDB2E8FEDDBEF6F crc64:5B2AE15BCF95E009 figure legend:Fig. 4A, Fig. 5|comment:caf40 and caf130 deletions do not affect the formation of the CCR4-NOT complex.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:874BED882455E53A|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P53829 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564804|imex:IM-19283-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:5CDB2E8FEDDBEF6F crc64:F3DBABE6AD3C7F3C figure legend:Fig. 4A, Fig. 5|comment:caf40 and caf130 deletions do not affect the formation of the CCR4-NOT complex.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:874BED882455E53A|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31384 uniprotkb:P39008 intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564804|imex:IM-19283-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N - crc64:5CDB2E8FEDDBEF6F crc64:F3CAF97106A65933 figure legend:Fig. 4A, Fig. 5|comment:caf40 and caf130 deletions do not affect the formation of the CCR4-NOT complex.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:874BED882455E53A|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25655 uniprotkb:P53829 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564812|imex:IM-19283-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:5B2AE15BCF95E009 crc64:F3DBABE6AD3C7F3C figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:EDC59D6728C892FD|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25655 uniprotkb:P39008 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-13629|uniprotkb:D6W1M7|ensemblfungi:YNR052C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:pop2_yeast(display_long)|uniprotkb:POP2(gene name)|psi-mi:POP2(display_short)|uniprotkb:CAF1(gene name synonym)|uniprotkb:YNR052C(locus name)|uniprotkb:N3470(orf name)|uniprotkb:CCR4-associated factor 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564812|imex:IM-19283-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000005335|ensemblfungi:YNR052C(gene)|ensemblfungi:YNR052C_mRNA(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0043332"(mating projection tip)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR006941(Ribonuclease CAF1)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039637|rcsb pdb:1UOC|rcsb pdb:4B8A|rcsb pdb:4B8C|refseq:NP_014450.3|mint:P39008|dip:DIP-1957N - crc64:5B2AE15BCF95E009 crc64:F3CAF97106A65933 figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:9MOxi5VbfC199pktTp/lOroQiSA559292 intact-crc:EDC59D6728C892FD|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25655 uniprotkb:P31384 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564812|imex:IM-19283-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C - crc64:5B2AE15BCF95E009 crc64:5CDB2E8FEDDBEF6F figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:EDC59D6728C892FD|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25655 uniprotkb:P53280 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564812|imex:IM-19283-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:5B2AE15BCF95E009 crc64:BF3542816CC78490 figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:EDC59D6728C892FD|rigid:P4ftKVfM7lfTA2j9EGwITr9WVp4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P25655 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564854|imex:IM-19283-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:F3DBABE6AD3C7F3C crc64:5B2AE15BCF95E009 figure legend:Fig. 4B|comment:Interactions observed in a pop2 -/- cell line.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:BBEDE647349DA72D|rigid:uJ/Y9s33nutL1beShlDWdWmxnGU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P53280 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564854|imex:IM-19283-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:F3DBABE6AD3C7F3C crc64:BF3542816CC78490 figure legend:Fig. 4B|comment:Interactions observed in a pop2 -/- cell line.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:BBEDE647349DA72D|rigid:uJ/Y9s33nutL1beShlDWdWmxnGU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P53280 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0071"(molecular sieving) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564798|imex:IM-19283-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:F3DBABE6AD3C7F3C crc64:BF3542816CC78490 figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:4FBF06FA63CE82F4|rigid:q0dpG70TeIYYokDrYujTTuG7sPU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P06102 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-12165|uniprotkb:D6VVP4|uniprotkb:Q6B233|ensemblfungi:YIL038C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:not3_yeast(display_long)|uniprotkb:NOT3(gene name)|psi-mi:NOT3(display_short)|uniprotkb:YIL038C(locus name) psi-mi:"MI:0071"(molecular sieving) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564798|imex:IM-19283-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR038635|interpro:IPR040168|ensemblfungi:YIL038C(gene)|ensemblfungi:YIL038C_mRNA(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|refseq:NP_012226.3|sgd:S000001300|dip:DIP-2256N|mint:P06102 - crc64:F3DBABE6AD3C7F3C crc64:69B76694FCC6846F figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:EfakZPDNU3FZeI5+rnu7YV1UsCg559292 intact-crc:4FBF06FA63CE82F4|rigid:q0dpG70TeIYYokDrYujTTuG7sPU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53829 uniprotkb:P31384 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-4396|uniprotkb:D6VPJ7|ensemblfungi:YAL021C psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:ccr4_yeast(display_long)|uniprotkb:CCR4(gene name)|psi-mi:CCR4(display_short)|uniprotkb:Carbon catabolite repressor protein 4(gene name synonym)|uniprotkb:Cytoplasmic deadenylase(gene name synonym)|uniprotkb:Glucose-repressible alcohol dehydrogenase transcriptional effector(gene name synonym)|uniprotkb:FUN27(orf name)|uniprotkb:YAL021C(locus name) psi-mi:"MI:0071"(molecular sieving) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564798|imex:IM-19283-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_009381.1|sgd:S000000019|dip:DIP-2522N|mint:P31384|ensemblfungi:YAL021C(gene)|ensemblfungi:YAL021C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004535"("poly(A)-specific ribonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007089"(traversing start control point of mitotic cell cycle)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0048478"(replication fork protection)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR025875|interpro:IPR032675|interpro:IPR036691|rcsb pdb:4B8C - crc64:F3DBABE6AD3C7F3C crc64:5CDB2E8FEDDBEF6F figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:f5gxp32WdxKuHQnE8O9/EhhA3Gw559292 intact-crc:4FBF06FA63CE82F4|rigid:q0dpG70TeIYYokDrYujTTuG7sPU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P25655 uniprotkb:P53829 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564871|imex:IM-19283-8 author score:44 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:5B2AE15BCF95E009 crc64:F3DBABE6AD3C7F3C figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:32897117DB5B57AF|rigid:isaYayYhAW9IbzmUvfvFVgG+ub0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53280 uniprotkb:P25655 intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564877|imex:IM-19283-9 author score:82 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 - crc64:BF3542816CC78490 crc64:5B2AE15BCF95E009 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 intact-crc:9EFE131511A5850C|rigid:bdK1j/qzdC84Hpw/TioyAJudAEs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:A5YKK6 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-1222758|uniprotkb:Q68DX7|uniprotkb:Q7Z3K2|uniprotkb:Q8IWB8|uniprotkb:Q8TB53|uniprotkb:Q9BVZ6|uniprotkb:Q9UFR8|uniprotkb:Q9UI27|uniprotkb:Q9Y2L0|intact:EBI-2561986|ensembl:ENSP00000320949 psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:cnot1_human(display_long)|uniprotkb:CNOT1(gene name)|psi-mi:CNOT1(display_short)|uniprotkb:CDC39(gene name synonym)|uniprotkb:KIAA1007(gene name synonym)|uniprotkb:NOT1(gene name synonym)|uniprotkb:Negative regulator of transcription subunit 1 homolog(gene name synonym)|uniprotkb:CCR4-associated factor 1(gene name synonym)|uniprotkb:AD-005(orf name) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564884|imex:IM-19283-10 author score:700 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 refseq:NP_057368.3|refseq:NP_996882.1|refseq:NP_001252541.1|dip:DIP-44954N|ensembl:ENSG00000125107(gene)|ensembl:ENST00000317147(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010606"(positive regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR038535|interpro:IPR040398|mint:A5YKK6|rcsb pdb:4C0D|rcsb pdb:4CQO|rcsb pdb:4CRU|rcsb pdb:4CRV|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT6|rcsb pdb:4CT7|rcsb pdb:4GMJ|rcsb pdb:4GML|rcsb pdb:4J8S|rcsb pdb:5ANR|rcsb pdb:5FU6|rcsb pdb:5FU7|rcsb pdb:5ONA|reactome:R-HSA-429947|reactome:R-HSA-6804115 - crc64:F3DBABE6AD3C7F3C - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:qYUeacTR9wuDH02Uy8CqCcaaXOY9606 intact-crc:AA79479928FD16CE|rigid:ru3VdZVjE0/0A5CcsvxFXn4eLxE false - sufficient binding region:1000-2376 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P22204 uniprotkb:P53829 intact:EBI-5569|uniprotkb:D6VUM4|ensemblfungi:YGR092W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:dbf2_yeast(display_long)|uniprotkb:DBF2(gene name)|psi-mi:DBF2(display_short)|uniprotkb:Dumbbell forming protein 2(gene name synonym)|uniprotkb:YGR092W(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564891|imex:IM-19283-11 author score:940 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003324|refseq:NP_011606.3|dip:DIP-2319N|reactome:R-SCE-2028269|ensemblfungi:YGR092W(gene)|ensemblfungi:YGR092W_mRNA(transcript)|go:"GO:0000280"(nuclear division)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007049"(cell cycle)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034973"(Sid2-Mob1 complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901900"(regulation of protein localization to cell division site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|rcsb pdb:5NCN refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:648C565D5CE7117D crc64:F3DBABE6AD3C7F3C figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:+HNtG1zL+t9L3ITf/MH16z6H5uY559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:6D324AADA80E0FEC|rigid:dBv40dWLXR4ZgRGrIVu6suCyoIg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53829 uniprotkb:Q9HE02 intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W intact:EBI-2564896|ensemblfungi:"SPAC589.02c.1:pep" psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:ssn2_schpo(display_long)|uniprotkb:srb9(gene name)|psi-mi:srb9(display_short)|uniprotkb:med13(gene name synonym)|uniprotkb:trap240(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B srb9(gene name synonym)|uniprotkb:SPAC589.02c(orf name) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564913|imex:IM-19283-12 author score:1000 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 interpro:IPR009401(TRAP240)|refseq:NP_594050.2|ensemblfungi:SPAC589.02c(gene)|ensemblfungi:SPAC589.02c.1(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter) - crc64:F3DBABE6AD3C7F3C - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 rogid:28khDLnjNSnwxh0VsKa9f9/EGMY284812 intact-crc:13D8960DE0206310|rigid:3hUcPrngxeFdKAlgFDkiFlWMdlU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P34909 uniprotkb:P53829 intact:EBI-12174|uniprotkb:D3DLX3|ensemblfungi:YER068W intact:EBI-28306|uniprotkb:D6W0Q5|ensemblfungi:YNL288W psi-mi:not4_yeast(display_long)|uniprotkb:MOT2(gene name)|psi-mi:MOT2(display_short)|uniprotkb:CCL1(gene name synonym)|uniprotkb:NOT4(gene name synonym)|uniprotkb:SIG1(gene name synonym)|uniprotkb:SSF1(gene name synonym)|uniprotkb:Modulator of transcription 2(gene name synonym)|uniprotkb:YER068W(locus name) psi-mi:caf40_yeast(display_long)|uniprotkb:YNL288W(locus name)|uniprotkb:N0540(orf name)|uniprotkb:40 kDa CCR4-associated factor(gene name synonym)|uniprotkb:CAF40(gene name)|psi-mi:CAF40(display_short) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564918|imex:IM-19283-13 author score:820 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YER068W(gene)|ensemblfungi:YER068W_mRNA(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034261|interpro:IPR035979|interpro:IPR039515|interpro:IPR039780|rcsb pdb:5AIE|rcsb pdb:5AJD|refseq:NP_010991.3|sgd:S000000870|dip:DIP-2255N|mint:P34909 refseq:NP_014111.1|sgd:S000005232|dip:DIP-1995N|mint:P53829|ensemblfungi:YNL288W(gene)|ensemblfungi:YNL288W_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007216(Cell differentiation, Rcd1-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4CV5 - crc64:8847084BD9BF48B7 crc64:F3DBABE6AD3C7F3C figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:TLt8Wu8+ygYk/0dtfXHhnCITKqc559292 rogid:etuSSgFGQOcgxPDexEXUqQg6H5s559292 intact-crc:6531FE412B70C586|rigid:8cVnmhmeEe1Ac03UONcz0T2ajoA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P53280 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564923|imex:IM-19283-14 author score:"NOT1(1-667) 1500, NOT1(1152-2108) 1900" - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:5B2AE15BCF95E009 crc64:BF3542816CC78490 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:473627F62145061A|rigid:bdK1j/qzdC84Hpw/TioyAJudAEs false sufficient binding region:1-667|sufficient binding region:1152-2108 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12514 uniprotkb:P53280 intact:EBI-12184|uniprotkb:D6W476|ensemblfungi:YPR072W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:not5_yeast(display_long)|uniprotkb:NOT5(gene name)|psi-mi:NOT5(display_short)|uniprotkb:YP9499.27(orf name)|uniprotkb:YPR072W(locus name) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0018"(two hybrid) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564932|imex:IM-19283-15 author score:29 - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPR072W(gene)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|rcsb pdb:4BY6|rcsb pdb:6TB3|ensemblfungi:YPR072W_mRNA(transcript)|refseq:NP_015397.1|sgd:S000006276|dip:DIP-2257N|mint:Q12514 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:073137119B3E92BC crc64:BF3542816CC78490 figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:+XON8Ps4xCFhw058U9d2voUy2dc559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:446F949645F70189|rigid:3c4pwol9Pt7kA2FXBJ1yft4sHm4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25655 uniprotkb:P53280 intact:EBI-12139|uniprotkb:D6VR93|ensemblfungi:YCR093W intact:EBI-23322|uniprotkb:D6VUR6|ensemblfungi:YGR134W psi-mi:not1_yeast(display_long)|uniprotkb:CDC39(gene name)|psi-mi:CDC39(display_short)|uniprotkb:NOT1(gene name synonym)|uniprotkb:ROS1(gene name synonym)|uniprotkb:YCR093W(locus name)|uniprotkb:YCR93W(orf name)|uniprotkb:YCR1151(orf name)|uniprotkb:Cell division cycle protein 39(gene name synonym) psi-mi:cf130_yeast(display_long)|uniprotkb:CAF130(gene name)|psi-mi:CAF130(display_short)|uniprotkb:130 kDa CCR4-associated factor(gene name synonym)|uniprotkb:YGR134W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chen et al. (2001) pubmed:11733989|imex:IM-19283 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2564945|imex:IM-19283-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YCR093W(gene)|ensemblfungi:YCR093W_mRNA(transcript)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0000932"(P-body)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|interpro:IPR007196(CCR4-Not complex component, Not1)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR024557|interpro:IPR032191|interpro:IPR032193|interpro:IPR032194|interpro:IPR032195|interpro:IPR038535|interpro:IPR040398|rcsb pdb:4B89|rcsb pdb:4B8A|rcsb pdb:4B8B|rcsb pdb:4B8C|rcsb pdb:4BY6|rcsb pdb:4CV5|rcsb pdb:5AJD|refseq:NP_010017.2|sgd:S000000689|dip:DIP-1202N|mint:P25655 sgd:S000003366|refseq:NP_011650.3|dip:DIP-2683N|mint:P53280|ensemblfungi:YGR134W(gene)|ensemblfungi:YGR134W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter) - crc64:5B2AE15BCF95E009 crc64:BF3542816CC78490 figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/01/29 2014/10/16 rogid:k2j2eOcKShGEaNVLDNiTdtYVqBI559292 rogid:CSxzq8xaTnSTHKdL1MjIB8QIPjk559292 intact-crc:978F6DA282EA55D9|rigid:bdK1j/qzdC84Hpw/TioyAJudAEs false tag:?-?|sufficient binding region:1-667|sufficient binding region:1152-2108 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)