#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q4R5M2 uniprotkb:P41222 intact:EBI-7552845|intact:MINT-7266161|ensembl:ENSMFAP00000060243 intact:EBI-948821|ensembl:ENSP00000360687|uniprotkb:Q9UC22|uniprotkb:Q5SQ10|uniprotkb:Q7M4P3|uniprotkb:Q9UCC9|uniprotkb:Q9UCD9|uniprotkb:B2R727 psi-mi:catb_macfa(display_long)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:QccE-13673(orf name) psi-mi:ptgds_human(display_long)|uniprotkb:Lipocalin-type prostaglandin-D synthase(gene name synonym)|uniprotkb:Glutathione-independent PGD synthase(gene name synonym)|uniprotkb:Prostaglandin-D2 synthase(gene name synonym)|uniprotkb:Beta-trace protein(gene name synonym)|uniprotkb:Cerebrin-28(gene name synonym)|uniprotkb:PTGDS(gene name)|psi-mi:PTGDS(display_short)|uniprotkb:PDS(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nagata et al. (2009) pubmed:19878301|imex:IM-15531|mint:MINT-7266155|doi:10.1111/j.1742-4658.2009.07426 taxid:9541(macfa)|taxid:9541("Macaca fascicularis (Crab-eating macaque)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7552882|mint:MINT-7266176|imex:IM-15531-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001270414.1|ensembl:ENSMFAG00000014829(gene)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0016324"(apical plasma membrane)|ensembl:ENSMFAT00000090811(transcript)|go:"GO:0042470"(melanosome)|go:"GO:0050790"(regulation of catalytic activity)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:Q4R5M2|mint:MINT-7266178(identity) ensembl:ENSG00000107317(gene)|ensembl:ENST00000371625(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0004667"(prostaglandin-D synthase activity)|go:"GO:0005501"(retinoid binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036094"(small molecule binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR002972(Prostaglandin D synthase)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P41222|rcsb pdb:2WWP|rcsb pdb:3O19|rcsb pdb:3O22|rcsb pdb:3O2Y|rcsb pdb:4IMN|rcsb pdb:4IMO|rcsb pdb:4ORR|rcsb pdb:4ORS|rcsb pdb:4ORU|rcsb pdb:4ORW|rcsb pdb:4ORX|rcsb pdb:4ORY|rcsb pdb:4OS0|rcsb pdb:4OS3|rcsb pdb:4OS8|rcsb pdb:5WY9|reactome:R-HSA-2162123|reactome:R-HSA-9690406|refseq:NP_000945.3|mint:MINT-7266179(identity) go:"GO:0005764"(lysosome) comment:mint - figure legend:F4C|comment:mint|comment:We used the human Uniprot ID of L-PGDS protein instead of the Macaca fascicularis one.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9541(macfa-kidney)|taxid:9541(Macaca fascicularis) - 2009/10/01 2014/10/16 rogid:Vh3bUQEFVumj5mesA8F1rTRrUnc9541 rogid:hqvCVc1a1AWLCZWiYWgA4vPZNtk9606 intact-crc:D8903873B0835342|rigid:jPYKnsd6uIEqxKrb0NaObSxgd0Y false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining) uniprotkb:Q4R4P0 uniprotkb:P41222 intact:EBI-7552913|intact:MINT-7266195 intact:EBI-948821|ensembl:ENSP00000360687|uniprotkb:Q9UC22|uniprotkb:Q5SQ10|uniprotkb:Q7M4P3|uniprotkb:Q9UCC9|uniprotkb:Q9UCD9|uniprotkb:B2R727 psi-mi:q4r4p0_macfa(display_long) psi-mi:ptgds_human(display_long)|uniprotkb:Lipocalin-type prostaglandin-D synthase(gene name synonym)|uniprotkb:Glutathione-independent PGD synthase(gene name synonym)|uniprotkb:Prostaglandin-D2 synthase(gene name synonym)|uniprotkb:Beta-trace protein(gene name synonym)|uniprotkb:Cerebrin-28(gene name synonym)|uniprotkb:PTGDS(gene name)|psi-mi:PTGDS(display_short)|uniprotkb:PDS(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Nagata et al. (2009) pubmed:19878301|imex:IM-15531|mint:MINT-7266155|doi:10.1111/j.1742-4658.2009.07426 taxid:9541(macfa)|taxid:9541("Macaca fascicularis (Crab-eating macaque)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7552924|mint:MINT-7266187|imex:IM-15531-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q4R4P0|interpro:IPR033121|interpro:IPR033144|interpro:IPR021109|interpro:IPR001461(Peptidase A1)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|mint:MINT-7266192(identity) ensembl:ENSG00000107317(gene)|ensembl:ENST00000371625(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0004667"(prostaglandin-D synthase activity)|go:"GO:0005501"(retinoid binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036094"(small molecule binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR002972(Prostaglandin D synthase)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P41222|rcsb pdb:2WWP|rcsb pdb:3O19|rcsb pdb:3O22|rcsb pdb:3O2Y|rcsb pdb:4IMN|rcsb pdb:4IMO|rcsb pdb:4ORR|rcsb pdb:4ORS|rcsb pdb:4ORU|rcsb pdb:4ORW|rcsb pdb:4ORX|rcsb pdb:4ORY|rcsb pdb:4OS0|rcsb pdb:4OS3|rcsb pdb:4OS8|rcsb pdb:5WY9|reactome:R-HSA-2162123|reactome:R-HSA-9690406|refseq:NP_000945.3|mint:MINT-7266190(identity) go:"GO:0005764"(lysosome) comment:mint - figure legend:F4D|comment:mint|comment:We used the human Uniprot ID of L-PGDS protein instead of the Macaca fascicularis one.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9541(macfa-kidney)|taxid:9541(Macaca fascicularis) - 2009/10/01 2014/10/16 rogid:q6kbrpQganTUcNl3DORitQo5/6s9541 rogid:hqvCVc1a1AWLCZWiYWgA4vPZNtk9606 intact-crc:9EDCEF649B2D0D49|rigid:4ldXJgNe1HENSOhXfFtcS3df7no false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0708"(monoclonal antibody immunostaining)