#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P47035	uniprotkb:Q02208	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212704|imex:IM-20243-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:80EDF9A8065EB5A2	-	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:EDF910316761FE0F|rigid:2g+MioRBGhDhgaryNssK4rxr4Ew	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P47035	uniprotkb:Q00684	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212704|imex:IM-20243-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	-	crc64:80EDF9A8065EB5A2	crc64:4EB3985DFA3FD823	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:EDF910316761FE0F|rigid:2g+MioRBGhDhgaryNssK4rxr4Ew	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P47035	uniprotkb:P06700	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212704|imex:IM-20243-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	-	crc64:80EDF9A8065EB5A2	crc64:52E6937533654586	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	intact-crc:EDF910316761FE0F|rigid:2g+MioRBGhDhgaryNssK4rxr4Ew	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:Q06142	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-9145|ensemblfungi:YLR347C|uniprotkb:D6VYY6	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:imb1_yeast(display_long)|uniprotkb:KAP95(gene name)|psi-mi:KAP95(display_short)|uniprotkb:YLR347C(locus name)|uniprotkb:L8300.15(orf name)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Karyopherin-95(gene name synonym)|uniprotkb:Importin-95(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	rcsb pdb:3EA5|rcsb pdb:3ND2|rcsb pdb:5OWU|reactome:R-SCE-2995383|reactome:R-SCE-6798695|ensemblfungi:YLR347C(gene)|ensemblfungi:YLR347C_mRNA(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060188"(regulation of protein desumoylation)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|rcsb pdb:2BKU|go:"GO:0006612"(protein targeting to membrane)|refseq:NP_013451.1|sgd:S000004339|dip:DIP-2357N|mint:Q06142	-	crc64:52E6937533654586	crc64:ED530F5313E75B06	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:ebWeXaUKiBFWgjdv9s2pz1GIqgI559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:P06701	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701	-	crc64:52E6937533654586	crc64:CA2503D7645397AC	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:P21691	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-17211|uniprotkb:D6VXG2|ensemblfungi:YKR101W	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:sir1_yeast(display_long)|uniprotkb:SIR1(gene name)|psi-mi:SIR1(display_short)|uniprotkb:YKR101W(locus name)|uniprotkb:Silent information regulator 1(gene name synonym)|uniprotkb:Heterochromatin protein SIR1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_013027.4|sgd:S000001809|ensemblfungi:YKR101W(gene)|ensemblfungi:YKR101W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR021646|interpro:IPR037240|rcsb pdb:1Z1A|rcsb pdb:1ZBX|rcsb pdb:1ZHI|dip:DIP-2453N|mint:P21691	-	crc64:52E6937533654586	crc64:00FEABD1BD35BC81	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:CMVYYG4cMH7Z2Gmq21uNeDyFqqU559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:Q12192	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-15023|uniprotkb:D6W2X8|ensemblfungi:YOR279C	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:rfm1_yeast(display_long)|uniprotkb:RFM1(gene name)|psi-mi:RFM1(display_short)|uniprotkb:YOR279C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	sgd:S000005805|refseq:NP_014922.3|ensemblfungi:YOR279C(gene)|ensemblfungi:YOR279C_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032298"(positive regulation of DNA-dependent DNA replication initiation)|dip:DIP-4430N|mint:Q12192	-	crc64:52E6937533654586	-	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:mM9jPExNCEs4dCtJ+Zy9dswWB6Y559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:P11978	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978	-	crc64:52E6937533654586	crc64:9C698765964F094E	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:Q02821	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	crc64:52E6937533654586	crc64:8D3A0CB76F2E7C00	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:P47035	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	crc64:52E6937533654586	crc64:80EDF9A8065EB5A2	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:Q00684	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	-	crc64:52E6937533654586	crc64:4EB3985DFA3FD823	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P06700	uniprotkb:Q02208	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212712|imex:IM-20243-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:52E6937533654586	-	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:584193E4BDE412AF|rigid:f5RJXPiudCdO1NQIWYu1Zlt1oDs	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:Q02892	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-12105|uniprotkb:D6W3S4|ensemblfungi:YPL093W	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:nog1_yeast(display_long)|uniprotkb:LPG15W(orf name)|uniprotkb:YPL093W(locus name)|uniprotkb:NOG1(gene name)|psi-mi:NOG1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	ensemblfungi:YPL093W(gene)|ensemblfungi:YPL093W_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005525"(GTP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|rcsb pdb:3JCT|rcsb pdb:4V7F|rcsb pdb:5FL8|rcsb pdb:5JCS|rcsb pdb:6C0F|rcsb pdb:6ELZ|rcsb pdb:6EM1|rcsb pdb:6FT6|rcsb pdb:6M62|rcsb pdb:6N8J|rcsb pdb:6N8K|rcsb pdb:6N8L|rcsb pdb:6YLG|rcsb pdb:6YLH|rcsb pdb:6YLX|rcsb pdb:6YLY|rcsb pdb:7BT6|rcsb pdb:7BTB|rcsb pdb:6EM5|refseq:NP_015232.1|sgd:S000006014|mint:Q02892|dip:DIP-2785N	-	crc64:2DC064120C5E7331	crc64:640324779AE4D716	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:ldS9KDRV01DnkO+7N5Xl5TZZVTI559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:P04786	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-19338|uniprotkb:D6W261|ensemblfungi:YOL006C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:top1_yeast(display_long)|uniprotkb:MAK1(gene name synonym)|uniprotkb:YOL006C(locus name)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:Maintenance of killer protein 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_014637.1|sgd:S000005366|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007059"(chromosome segregation)|ensemblfungi:YOL006C(gene)|ensemblfungi:YOL006C_mRNA(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|rcsb pdb:1OIS|go:"GO:0007076"(mitotic chromosome condensation)|reactome:R-SCE-4615885|go:"GO:0007097"(nuclear migration)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|dip:DIP-1705N|mint:P04786	-	crc64:2DC064120C5E7331	crc64:1FBD5FCED044C4A2	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:GWT5XbEStTacnnxE6XIN+4ylT3E559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:P21538	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-14905|uniprotkb:D6VQ49|ensemblfungi:YBR049C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:reb1_yeast(display_long)|uniprotkb:REB1(gene name)|psi-mi:REB1(display_short)|uniprotkb:GRF2(gene name synonym)|uniprotkb:YBR049C(locus name)|uniprotkb:YBR0502(orf name)|uniprotkb:QBP(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_009605.1|sgd:S000000253|ensemblfungi:YBR049C(gene)|ensemblfungi:YBR049C_mRNA(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001174"(transcriptional start site selection at RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|go:"GO:0000785"(chromatin)|dip:DIP-6374N|mint:P21538	-	crc64:2DC064120C5E7331	crc64:318EB17D20D004B6	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:VfwlaPZpEKGMfeaQz1Pib8UPoAQ559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:P47035	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	crc64:2DC064120C5E7331	crc64:80EDF9A8065EB5A2	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:Q02208	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:2DC064120C5E7331	-	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O13329	uniprotkb:Q00684	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212728|imex:IM-20243-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	-	crc64:2DC064120C5E7331	crc64:4EB3985DFA3FD823	figure legend:Fig 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:9D4C8E23030D40DA|rigid:zvztPC4nlUwzGS9bsE/0sZsuN/w	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q02208	uniprotkb:P25651	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212757|imex:IM-20243-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651	-	-	crc64:9650E0DA89B31CC5	figure legend:Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	intact-crc:8EC374A51F538A6C|rigid:/t9MlhnQDFylg+/ZHKMdTAM86qY	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q02208	uniprotkb:P47035	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212757|imex:IM-20243-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	-	crc64:80EDF9A8065EB5A2	figure legend:Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:8EC374A51F538A6C|rigid:/t9MlhnQDFylg+/ZHKMdTAM86qY	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q02208	uniprotkb:O13329	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212757|imex:IM-20243-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	-	-	crc64:2DC064120C5E7331	figure legend:Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	intact-crc:8EC374A51F538A6C|rigid:/t9MlhnQDFylg+/ZHKMdTAM86qY	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q02208	uniprotkb:Q00684	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	intact:EBI-4192|uniprotkb:Q05180|uniprotkb:Q05673|uniprotkb:D6VTQ8|ensemblfungi:YFR028C	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:cdc14_yeast(display_long)|uniprotkb:CDC14(gene name)|psi-mi:CDC14(display_short)|uniprotkb:OAF3(gene name synonym)|uniprotkb:YFR028C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212757|imex:IM-20243-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	sgd:S000001924|refseq:NP_116684.3|dip:DIP-5116N|mint:Q00684|ensemblfungi:YFR028C(gene)|ensemblfungi:YFR028C_mRNA(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000922"(spindle pole)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030869"(RENT complex)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0051229"(meiotic spindle disassembly)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903501"(positive regulation of mitotic actomyosin contractile ring assembly)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR026070|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|rcsb pdb:4ZJ7|rcsb pdb:5XW4|rcsb pdb:5XW5|rcsb pdb:6G84|rcsb pdb:6G85|rcsb pdb:6G86|reactome:R-SCE-176407|reactome:R-SCE-5687128	-	-	crc64:4EB3985DFA3FD823	figure legend:Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	rogid:BD4N0EbP9I/G2s3eSX55Qtq+4L8559292	intact-crc:8EC374A51F538A6C|rigid:/t9MlhnQDFylg+/ZHKMdTAM86qY	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q04087	uniprotkb:Q02821	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	intact:EBI-1797|uniprotkb:D6W0Z8|ensemblfungi:YNL189W	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:ima1_yeast(display_long)|uniprotkb:SRP1(gene name)|psi-mi:SRP1(display_short)|uniprotkb:KAP60(gene name synonym)|uniprotkb:YNL189W(locus name)|uniprotkb:N1606(orf name)|uniprotkb:Karyopherin subunit alpha(gene name synonym)|uniprotkb:Karyopherin-60(gene name synonym)|uniprotkb:Serine-rich RNA polymerase I suppressor protein(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212766|imex:IM-20243-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	refseq:NP_014210.1|sgd:S000005133|dip:DIP-728N|mint:Q02821|ensemblfungi:YNL189W(gene)|ensemblfungi:YNL189W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031144"(proteasome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|rcsb pdb:1BK5|rcsb pdb:1BK6|rcsb pdb:1EE4|rcsb pdb:1EE5|rcsb pdb:1UN0|rcsb pdb:1WA5|rcsb pdb:2C1T|rcsb pdb:4PVZ|rcsb pdb:4XZR|rcsb pdb:5H2W|rcsb pdb:5H2X|rcsb pdb:5T94	-	crc64:60D880BA947B9005	crc64:8D3A0CB76F2E7C00	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	rogid:NyzC93xnBCb8DX/AH346lwg4u2A559292	intact-crc:D8BDD52041153A2B|rigid:wPrI4vvKaLYLMLJ0gUaAqES4UwA	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q04087	uniprotkb:Q12066	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	intact:EBI-35877|uniprotkb:D6VRQ9|ensemblfungi:YDL089W	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:nur1_yeast(display_long)|uniprotkb:D2416(orf name)|uniprotkb:YDL089W(locus name)|uniprotkb:NUR1(gene name)|psi-mi:NUR1(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212766|imex:IM-20243-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	refseq:NP_010194.1|sgd:S000002247|dip:DIP-1799N|ensemblfungi:YDL089W(gene)|ensemblfungi:YDL089W_mRNA(transcript)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043007"(maintenance of rDNA)|interpro:IPR018819	-	crc64:60D880BA947B9005	crc64:3785895EA2887E89	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	rogid:ibRDv3E8nWUOup4UFnN90IeHfTs559292	intact-crc:D8BDD52041153A2B|rigid:wPrI4vvKaLYLMLJ0gUaAqES4UwA	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q04087	uniprotkb:P25651	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212766|imex:IM-20243-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651	-	crc64:60D880BA947B9005	crc64:9650E0DA89B31CC5	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	intact-crc:D8BDD52041153A2B|rigid:wPrI4vvKaLYLMLJ0gUaAqES4UwA	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q04087	uniprotkb:Q03707	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	intact:EBI-18064|uniprotkb:Q03712|uniprotkb:D6VZE1|ensemblfungi:YML034W	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:src1_yeast(display_long)|uniprotkb:YML033W(orf name)|uniprotkb:YML034W(locus name)|uniprotkb:SRC1(gene name)|psi-mi:SRC1(display_short)|uniprotkb:HEH1(gene name synonym)|uniprotkb:Helix-extension-helix domain-containing protein 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212766|imex:IM-20243-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	refseq:NP_013679.1|sgd:S000004497|ensemblfungi:YML034W(gene)|ensemblfungi:YML034W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043007"(maintenance of rDNA)|interpro:IPR018996|interpro:IPR025856|interpro:IPR041885|interpro:IPR044780|rcsb pdb:4XZR|dip:DIP-4546N|mint:Q03707	-	crc64:60D880BA947B9005	crc64:214CA064ECE160F4	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	rogid:YeIyXOJ+hN9AMRaZKqLZVXjv9p4559292	intact-crc:D8BDD52041153A2B|rigid:wPrI4vvKaLYLMLJ0gUaAqES4UwA	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25651	uniprotkb:Q03707	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	intact:EBI-18064|uniprotkb:Q03712|uniprotkb:D6VZE1|ensemblfungi:YML034W	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:src1_yeast(display_long)|uniprotkb:YML033W(orf name)|uniprotkb:YML034W(locus name)|uniprotkb:SRC1(gene name)|psi-mi:SRC1(display_short)|uniprotkb:HEH1(gene name synonym)|uniprotkb:Helix-extension-helix domain-containing protein 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212775|imex:IM-20243-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651	refseq:NP_013679.1|sgd:S000004497|ensemblfungi:YML034W(gene)|ensemblfungi:YML034W_mRNA(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034087"(establishment of mitotic sister chromatid cohesion)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043007"(maintenance of rDNA)|interpro:IPR018996|interpro:IPR025856|interpro:IPR041885|interpro:IPR044780|rcsb pdb:4XZR|dip:DIP-4546N|mint:Q03707	-	crc64:9650E0DA89B31CC5	crc64:214CA064ECE160F4	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	rogid:YeIyXOJ+hN9AMRaZKqLZVXjv9p4559292	intact-crc:29EC4989B89689C2|rigid:NcxRm6cJJ6GpxzyS5vCKZXHbIDU	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P25651	uniprotkb:Q04087	intact:EBI-22001|uniprotkb:D6VR86|ensemblfungi:YCR086W	intact:EBI-32189|uniprotkb:D6VT66|ensemblfungi:YDR439W	psi-mi:csm1_yeast(display_long)|uniprotkb:YCR086W(locus name)|uniprotkb:YCR86W(orf name)|uniprotkb:Chromosome segregation in meiosis protein 1(gene name synonym)|uniprotkb:CSM1(gene name)|psi-mi:CSM1(display_short)|uniprotkb:SPO86(gene name synonym)	psi-mi:lrs4_yeast(display_long)|uniprotkb:Loss of rDNA silencing protein 4(gene name synonym)|uniprotkb:LRS4(gene name)|psi-mi:LRS4(display_short)|uniprotkb:D9461.25(orf name)|uniprotkb:YDR439W(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212775|imex:IM-20243-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010009.1|sgd:S000000682|dip:DIP-1283N|ensemblfungi:YCR086W(gene)|ensemblfungi:YCR086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0042802"(identical protein binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045144"(meiotic sister chromatid segregation)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990644"(microtubule site clamp)|interpro:IPR020981|interpro:IPR038608|interpro:IPR040349|interpro:IPR041671|rcsb pdb:3N4R|rcsb pdb:3N4S|rcsb pdb:3N4X|rcsb pdb:3N7N|rcsb pdb:5KTB|rcsb pdb:5V1A|rcsb pdb:5V3N|rcsb pdb:6DEI|mint:P25651	refseq:NP_010727.1|sgd:S000002847|dip:DIP-1416N|mint:Q04087|ensemblfungi:YDR439W(gene)|ensemblfungi:YDR439W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0033551"(monopolin complex)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051455"(monopolar spindle attachment to meiosis I kinetochore)|go:"GO:0070550"(rDNA condensation)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR018479|rcsb pdb:3N7N	-	crc64:9650E0DA89B31CC5	crc64:60D880BA947B9005	figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:rN1hGW+i7AN2+SmrIrwqz4ZSbQk559292	rogid:XJ/t2ftZBXOTJshr/zQeMxci/6Q559292	intact-crc:29EC4989B89689C2|rigid:NcxRm6cJJ6GpxzyS5vCKZXHbIDU	false	calmodulin binding peptide plus protein a tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:P47035	uniprotkb:Q02208	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0416"(fluorescence microscopy)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212749|imex:IM-20243-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:80EDF9A8065EB5A2	-	figure legend:Fig 2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:4004D1259A64FD38|rigid:9BuOg/53clKoial703CrkNj6MVU	false	green fluorescent protein tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:P47035	uniprotkb:P06700	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212788|imex:IM-20243-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	-	crc64:80EDF9A8065EB5A2	crc64:52E6937533654586	figure legend:Fig S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	intact-crc:17632A8015798B1C|rigid:achXgxRAmzXrxN3mqdOJpbZvxlo	false	green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47035	uniprotkb:Q02208	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212788|imex:IM-20243-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:80EDF9A8065EB5A2	-	figure legend:Fig S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:17632A8015798B1C|rigid:achXgxRAmzXrxN3mqdOJpbZvxlo	false	green fluorescent protein tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06700	uniprotkb:P47035	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212797|imex:IM-20243-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	crc64:52E6937533654586	crc64:80EDF9A8065EB5A2	figure legend:Fig S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:028F03EF84B61F1B|rigid:achXgxRAmzXrxN3mqdOJpbZvxlo	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06700	uniprotkb:Q02208	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212797|imex:IM-20243-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:52E6937533654586	-	figure legend:Fig S1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:028F03EF84B61F1B|rigid:achXgxRAmzXrxN3mqdOJpbZvxlo	false	-	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O13329	uniprotkb:Q02208	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-27048|uniprotkb:D6VX76|ensemblfungi:YKR010C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:tof2_yeast(display_long)|uniprotkb:TOF2(gene name)|psi-mi:TOF2(display_short)|uniprotkb:YK109(orf name)|uniprotkb:YKR010C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212806|imex:IM-20243-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	sgd:S000001718|refseq:NP_012935.3|mint:Q02208|dip:DIP-3803N|ensemblfungi:YKR010C(gene)|ensemblfungi:YKR010C_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007000"(nucleolus organization)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0070550"(rDNA condensation)|interpro:IPR018844|interpro:IPR043185|rcsb pdb:5HOI|rcsb pdb:5V3N	-	crc64:2DC064120C5E7331	-	figure legend:Fig S1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:JSZUcVEWUE0GXXKxkdC/l5MWeLc559292	intact-crc:B00DD5AB89FB9E04|rigid:bYKHr+miu8nprEhmhx5VdXcBiLI	false	myc tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O13329	uniprotkb:P06700	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212806|imex:IM-20243-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	-	crc64:2DC064120C5E7331	crc64:52E6937533654586	figure legend:Fig S1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	intact-crc:B00DD5AB89FB9E04|rigid:bYKHr+miu8nprEhmhx5VdXcBiLI	false	myc tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O13329	uniprotkb:P47035	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-25953|uniprotkb:D6VWA8|ensemblfungi:YJL076W	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:net1_yeast(display_long)|uniprotkb:YJL076W(locus name)|uniprotkb:J1038(orf name)|uniprotkb:NET1(gene name)|psi-mi:NET1(display_short)|uniprotkb:CFI1(gene name synonym)|uniprotkb:ESC5(gene name synonym)|uniprotkb:SRM8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212815|imex:IM-20243-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_012459.1|sgd:S000003612|mint:P47035|dip:DIP-5153N|ensemblfungi:YJL076W(gene)|ensemblfungi:YJL076W_mRNA(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001100"(negative regulation of exit from mitosis)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0007000"(nucleolus organization)|go:"GO:0007049"(cell cycle)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030869"(RENT complex)|go:"GO:0031030"(negative regulation of septation initiation signaling)|go:"GO:0051301"(cell division)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR018844|interpro:IPR043185	-	crc64:2DC064120C5E7331	crc64:80EDF9A8065EB5A2	figure legend:Fig S1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:yjUIbOfA/bCZE9nMIjYS1QTn6EI559292	intact-crc:54DF52881C4E0725|rigid:ELWo29YLFaJgI/vX8cjzanj4fSc	false	myc tag:c-c	ha tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O13329	uniprotkb:P06700	intact:EBI-7040|uniprotkb:Q04587|uniprotkb:D6VS96|ensemblfungi:YDR110W	intact:EBI-17219|uniprotkb:D6VRV4|ensemblfungi:YDL042C	psi-mi:fob1_yeast(display_long)|uniprotkb:FOB1(gene name)|psi-mi:FOB1(display_short)|uniprotkb:YD9727.06(orf name)|uniprotkb:HRM1(gene name synonym)|uniprotkb:YDR110W(locus name)	psi-mi:sir2_yeast(display_long)|uniprotkb:SIR2(gene name)|psi-mi:SIR2(display_short)|uniprotkb:MAR1(gene name synonym)|uniprotkb:YDL042C(locus name)|uniprotkb:D2714(orf name)|uniprotkb:Silent information regulator 2(gene name synonym)|uniprotkb:Regulatory protein SIR2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Huang et al. (2006)	pubmed:17043313|imex:IM-20243	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-2212815|imex:IM-20243-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002517|refseq:NP_010395.1|dip:DIP-870N|ensemblfungi:YDR110W(gene)|ensemblfungi:YDR110W_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0005730"(nucleolus)|go:"GO:0006310"(DNA recombination)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007580"(extrachromosomal circular DNA accumulation involved in cell aging)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043110"(rDNA spacer replication fork barrier binding)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045911"(positive regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0070550"(rDNA condensation)|go:"GO:0090342"(regulation of cell aging)	refseq:NP_010242.1|sgd:S000002200|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0070403"(NAD+ binding)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0097752"(regulation of DNA stability)|go:"GO:1904524"(negative regulation of DNA amplification)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR007654(Protein of unknown function DUF592)|interpro:IPR026590|interpro:IPR029035|rcsb pdb:2HJH|rcsb pdb:4IAO|go:"GO:0034398"(telomere tethering at nuclear periphery)|ensemblfungi:YDL042C_mRNA(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0016740"(transferase activity)|ensemblfungi:YDL042C(gene)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030869"(RENT complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|dip:DIP-596N|mint:P06700	-	crc64:2DC064120C5E7331	crc64:52E6937533654586	figure legend:Fig S1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2009/01/23	2014/10/16	rogid:TvQrwc5mRmjiQQGPCo5cjtiXE54559292	rogid:HSrFe/tNeIjMNN3xB+3h7rocgkU559292	intact-crc:54DF52881C4E0725|rigid:ELWo29YLFaJgI/vX8cjzanj4fSc	false	myc tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)