#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11974	uniprotkb:P00563	intact:EBI-7133357|intact:MINT-6824949|uniprotkb:O18919|uniprotkb:Q29501	intact:EBI-2750756	psi-mi:kpym_rabit(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:kcrm_rabit(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0013"(biophysical)	Sears et al. (1999)	pubmed:10555970|mint:MINT-6825820|doi:10.1021/bi991076e	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7133393|mint:MINT-6825826	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P11974|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|rcsb pdb:1A49|rcsb pdb:1A5U|rcsb pdb:1AQF|rcsb pdb:1F3W|rcsb pdb:1F3X|rcsb pdb:1PKN|rcsb pdb:2G50|rcsb pdb:3N25|refseq:NP_001182574.1|refseq:NP_001182573.1|dip:DIP-47514N|mint:MINT-6825830(identity)|uniprotkb:P11974(P11974)	interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:NP_001075708.1|interpro:IPR000749("ATP:guanido phosphotransferase")|rcsb pdb:1U6R|rcsb pdb:2CRK|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009408"(response to heat)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR036802|mint:P00563|mint:MINT-6825827(identity)|uniprotkb:P00563(P00563)	-	comment:mint|function:"Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP"	-	figure legend:F1|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:oHQI4W/ix1kaSA2xfXYpnn2l8Tw9986	rogid:m2yat412XZ2tXBXs3yBA8EJjhQs9986	intact-crc:D5F06A7C089B5A9B|rigid:ti1HMkAlM1dOn3lot33/X4lWrm8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11974	uniprotkb:P00563	intact:EBI-7133357|intact:MINT-6824949|uniprotkb:O18919|uniprotkb:Q29501	intact:EBI-2750756	psi-mi:kpym_rabit(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:kcrm_rabit(display_long)|uniprotkb:CKM(gene name)|psi-mi:CKM(display_short)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0013"(biophysical)	Sears et al. (1999)	pubmed:10555970|mint:MINT-6825820|doi:10.1021/bi991076e	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7133420|mint:MINT-6825833	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P11974|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|rcsb pdb:1A49|rcsb pdb:1A5U|rcsb pdb:1AQF|rcsb pdb:1F3W|rcsb pdb:1F3X|rcsb pdb:1PKN|rcsb pdb:2G50|rcsb pdb:3N25|refseq:NP_001182574.1|refseq:NP_001182573.1|dip:DIP-47514N|mint:MINT-6825837(identity)|uniprotkb:P11974(P11974)	interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|refseq:NP_001075708.1|interpro:IPR000749("ATP:guanido phosphotransferase")|rcsb pdb:1U6R|rcsb pdb:2CRK|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0009408"(response to heat)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR036802|mint:P00563|mint:MINT-6825834(identity)|uniprotkb:P00563(P00563)	-	comment:mint|function:"Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP"	-	figure legend:F4|comment:mint	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2009/01/23	2014/10/16	rogid:oHQI4W/ix1kaSA2xfXYpnn2l8Tw9986	rogid:m2yat412XZ2tXBXs3yBA8EJjhQs9986	intact-crc:CB6686C8443EF463|rigid:ti1HMkAlM1dOn3lot33/X4lWrm8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)