#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35082	uniprotkb:P17553	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570853|ensembl:ENSMUSP00000000127	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt3_mouse(display_long)|uniprotkb:Wnt3(gene name)|psi-mi:Wnt3(display_short)|uniprotkb:Int-4(gene name synonym)|uniprotkb:Wnt-3(gene name synonym)|uniprotkb:Proto-oncogene Int-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570867|imex:IM-19248-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	refseq:NP_033547.1|dip:DIP-39897N|ensembl:ENSMUSG00000000125(gene)|ensembl:ENSMUST00000000127(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698	-	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:vP6eVd9KwNAnrQhwXawT3eDoiz410090	intact-crc:A054EDF1A175AF3E|rigid:gabNY7iYJ4FmuL15/WPMsVN5jZU	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35082	uniprotkb:P17553	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570853|ensembl:ENSMUSP00000000127	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt3_mouse(display_long)|uniprotkb:Wnt3(gene name)|psi-mi:Wnt3(display_short)|uniprotkb:Int-4(gene name synonym)|uniprotkb:Wnt-3(gene name synonym)|uniprotkb:Proto-oncogene Int-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570876|imex:IM-19248-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	refseq:NP_033547.1|dip:DIP-39897N|ensembl:ENSMUSG00000000125(gene)|ensembl:ENSMUST00000000127(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698	-	-	-	figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:vP6eVd9KwNAnrQhwXawT3eDoiz410090	intact-crc:B2DAA131EC6AB99D|rigid:gabNY7iYJ4FmuL15/WPMsVN5jZU	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17553	uniprotkb:O35082	intact:EBI-1570853|ensembl:ENSMUSP00000000127	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	psi-mi:wnt3_mouse(display_long)|uniprotkb:Wnt3(gene name)|psi-mi:Wnt3(display_short)|uniprotkb:Int-4(gene name synonym)|uniprotkb:Wnt-3(gene name synonym)|uniprotkb:Proto-oncogene Int-4(gene name synonym)	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570885|imex:IM-19248-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033547.1|dip:DIP-39897N|ensembl:ENSMUSG00000000125(gene)|ensembl:ENSMUST00000000127(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	-	-	-	figure legend:S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:vP6eVd9KwNAnrQhwXawT3eDoiz410090	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	intact-crc:7984CDA426592C50|rigid:gabNY7iYJ4FmuL15/WPMsVN5jZU	false	ha tag:?-?	flag tag:c-c|binding-associated region:1-285	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04426	uniprotkb:O35082	intact:EBI-1570911|ensembl:ENSMUSP00000023734	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	psi-mi:wnt1_mouse(display_long)|uniprotkb:Wnt1(gene name)|psi-mi:Wnt1(display_short)|uniprotkb:Int-1(gene name synonym)|uniprotkb:Wnt-1(gene name synonym)|uniprotkb:Proto-oncogene Int-1(gene name synonym)	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570927|imex:IM-19248-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067254.1|dip:DIP-39896N|ensembl:ENSMUSG00000022997(gene)|ensembl:ENSMUST00000023734(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021536"(diencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021588"(cerebellum formation)|go:"GO:0021797"(forebrain anterior/posterior pattern specification)|go:"GO:0022004"(midbrain-hindbrain boundary maturation during brain development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022037"(metencephalon development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0030901"(midbrain development)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060348"(bone development)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009139(Wnt-1 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086400|reactome:R-MMU-4641262	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:RIvVHDrFJM1B9GtcEv35A4nvVW010090	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	intact-crc:1BEC667E17D0BA1F|rigid:BHe+RvT/LkSvveVmEqJRkgL7uL4	false	ha tag:?-?	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35082	uniprotkb:P04426	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570911|ensembl:ENSMUSP00000023734	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt1_mouse(display_long)|uniprotkb:Wnt1(gene name)|psi-mi:Wnt1(display_short)|uniprotkb:Int-1(gene name synonym)|uniprotkb:Wnt-1(gene name synonym)|uniprotkb:Proto-oncogene Int-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570936|imex:IM-19248-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	refseq:NP_067254.1|dip:DIP-39896N|ensembl:ENSMUSG00000022997(gene)|ensembl:ENSMUST00000023734(transcript)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009611"(response to wounding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0021536"(diencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021551"(central nervous system morphogenesis)|go:"GO:0021588"(cerebellum formation)|go:"GO:0021797"(forebrain anterior/posterior pattern specification)|go:"GO:0022004"(midbrain-hindbrain boundary maturation during brain development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022037"(metencephalon development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0030901"(midbrain development)|go:"GO:0030917"(midbrain-hindbrain boundary development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033278"(cell proliferation in midbrain)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060061"(Spemann organizer formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060348"(bone development)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009139(Wnt-1 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086400|reactome:R-MMU-4641262	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:RIvVHDrFJM1B9GtcEv35A4nvVW010090	intact-crc:44A9FC5CE8450092|rigid:BHe+RvT/LkSvveVmEqJRkgL7uL4	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35082	uniprotkb:P22724	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570945|ensembl:ENSMUSP00000036580	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt4_mouse(display_long)|uniprotkb:Wnt4(gene name)|psi-mi:Wnt4(display_short)|uniprotkb:Wnt-4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570965|imex:IM-19248-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	refseq:NP_033549.1|ensembl:ENSMUSG00000036856(gene)|ensembl:ENSMUST00000045747(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0001889"(liver development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007548"(sex differentiation)|go:"GO:0008584"(male gonad development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033080"(immature T cell proliferation in thymus)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038030"(non-canonical Wnt signaling pathway via MAPK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048599"(oocyte development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061369"(negative regulation of testicular blood vessel morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072006"(nephron development)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0072273"(metanephric nephron morphogenesis)|go:"GO:2000019"(negative regulation of male gonad development)|go:"GO:2000066"(positive regulation of cortisol biosynthetic process)|go:"GO:2000180"(negative regulation of androgen biosynthetic process)|go:"GO:2000225"(negative regulation of testosterone biosynthetic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009142(Wnt-4 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-3238698|reactome:R-MMU-4086400|go:"GO:0008585"(female gonad development)	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:Mqq6P+QzlTQmFiPhRQdQeqzzS/U10090	intact-crc:E5EA2CF0D4700372|rigid:6CXjzUlwNTWu75Xq4mTAikGxYmI	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22724	uniprotkb:O35082	intact:EBI-1570945|ensembl:ENSMUSP00000036580	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	psi-mi:wnt4_mouse(display_long)|uniprotkb:Wnt4(gene name)|psi-mi:Wnt4(display_short)|uniprotkb:Wnt-4(gene name synonym)	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570974|imex:IM-19248-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033549.1|ensembl:ENSMUSG00000036856(gene)|ensembl:ENSMUST00000045747(transcript)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001823"(mesonephros development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0001889"(liver development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007548"(sex differentiation)|go:"GO:0008584"(male gonad development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010894"(negative regulation of steroid biosynthetic process)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030237"(female sex determination)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033080"(immature T cell proliferation in thymus)|go:"GO:0035239"(tube morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038030"(non-canonical Wnt signaling pathway via MAPK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048599"(oocyte development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060126"(somatotropin secreting cell differentiation)|go:"GO:0060129"(thyroid-stimulating hormone-secreting cell differentiation)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060748"(tertiary branching involved in mammary gland duct morphogenesis)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061184"(positive regulation of dermatome development)|go:"GO:0061205"(paramesonephric duct development)|go:"GO:0061369"(negative regulation of testicular blood vessel morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072006"(nephron development)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072034"(renal vesicle induction)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072164"(mesonephric tubule development)|go:"GO:0072174"(metanephric tubule formation)|go:"GO:0072210"(metanephric nephron development)|go:"GO:0072273"(metanephric nephron morphogenesis)|go:"GO:2000019"(negative regulation of male gonad development)|go:"GO:2000066"(positive regulation of cortisol biosynthetic process)|go:"GO:2000180"(negative regulation of androgen biosynthetic process)|go:"GO:2000225"(negative regulation of testosterone biosynthetic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009142(Wnt-4 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-3238698|reactome:R-MMU-4086400|go:"GO:0008585"(female gonad development)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:Mqq6P+QzlTQmFiPhRQdQeqzzS/U10090	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	intact-crc:BAAFB6D22BE5B9FF|rigid:6CXjzUlwNTWu75Xq4mTAikGxYmI	false	ha tag:?-?	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35082	uniprotkb:P22725	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570997|imex:IM-19248-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:5EE19CF09A7B8618|rigid:euCzeV67qLtpdakHhIgdFWLLgzc	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35082	uniprotkb:P22725	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	intact:EBI-1570983|ensembl:ENSMUSP00000064878|uniprotkb:Q8BM17|uniprotkb:Q8BMF9|uniprotkb:Q8VCV6	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:wnt5a_mouse(display_long)|uniprotkb:Wnt5a(gene name)|psi-mi:Wnt5a(display_short)|uniprotkb:Wnt-5a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1571006|imex:IM-19248-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	go:"GO:0061349"(planar cell polarity pathway involved in cardiac right atrium morphogenesis)|go:"GO:0061350"(planar cell polarity pathway involved in cardiac muscle tissue morphogenesis)|go:"GO:0061354"(planar cell polarity pathway involved in pericardium morphogenesis)|go:"GO:0062009"(secondary palate development)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090009"(primitive streak formation)|go:"GO:0090037"(positive regulation of protein kinase C signaling)|go:"GO:0090082"(positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097325"(melanocyte proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0061348"(planar cell polarity pathway involved in ventricular septum morphogenesis)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902379"(chemoattractant activity involved in axon guidance)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007494"(midgut development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021891"(olfactory bulb interneuron development)|go:"GO:0007165"(signal transduction)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0007254"(JNK cascade)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR005817(Wnt superfamily)|interpro:IPR018161|interpro:IPR026538|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698|reactome:R-MMU-4086398|reactome:R-MMU-4086400|reactome:R-MMU-4608870|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:1903827"|go:"GO:1904934"(negative regulation of cell proliferation in midbrain)|go:"GO:1904938"(planar cell polarity pathway involved in axon guidance)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904953"(Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|ensembl:ENSMUST00000063465(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSMUSG00000021994(gene)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0003138"(primary heart field specification)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003401"(axis elongation)|go:"GO:0003402"(planar cell polarity pathway involved in axis elongation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005115"(receptor tyrosine kinase-like orphan receptor binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0036517"(chemoattraction of serotonergic neuron axon)|go:"GO:0036518"(chemorepulsion of dopaminergic neuron axon)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046546"(development of primary male sexual characteristics)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048570"(notochord morphogenesis)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0048806"(genitalia development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0048850"(hypophysis morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051885"(positive regulation of timing of anagen)|go:"GO:0051964"(negative regulation of synapse assembly)|go:"GO:0060026"(convergent extension)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060029"(convergent extension involved in organogenesis)|go:"GO:0060065"(uterus development)|go:"GO:0060067"(cervix development)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0060068"(vagina development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060157"(urinary bladder development)|go:"GO:0060324"(face development)|go:"GO:0060599"(lateral sprouting involved in mammary gland duct morphogenesis)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060606"(tube closure)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060686"(negative regulation of prostatic bud formation)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0060775"(planar cell polarity pathway involved in gastrula mediolateral intercalation)|go:"GO:0060809"(mesodermal to mesenchymal transition involved in gastrulation)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061053"(somite development)|go:"GO:0061347"(planar cell polarity pathway involved in outflow tract morphogenesis)|refseq:NP_001243153.1|refseq:NP_033550.2|refseq:XP_006518987.1|refseq:XP_006518988.1|dip:DIP-39893N	-	-	-	figure legend:S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	rogid:G9K/LKijd3T0ccGcNchvUn+NHGE10090	intact-crc:01A406D265EE3C95|rigid:euCzeV67qLtpdakHhIgdFWLLgzc	false	myc tag:c-c	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17553	uniprotkb:O35082	intact:EBI-1570853|ensembl:ENSMUSP00000000127	intact:EBI-1570828|uniprotkb:O70175|uniprotkb:O70621|uniprotkb:B2RR78|ensembl:ENSMUSP00000077899	psi-mi:wnt3_mouse(display_long)|uniprotkb:Wnt3(gene name)|psi-mi:Wnt3(display_short)|uniprotkb:Int-4(gene name synonym)|uniprotkb:Wnt-3(gene name synonym)|uniprotkb:Proto-oncogene Int-4(gene name synonym)	psi-mi:klot_mouse(display_long)|uniprotkb:Kl(gene name)|psi-mi:Kl(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Liu et al. (2007)	pubmed:17690294|imex:IM-19248	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1570902|imex:IM-19248-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033547.1|dip:DIP-39897N|ensembl:ENSMUSG00000000125(gene)|ensembl:ENSMUST00000000127(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001707"(mesoderm formation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007276"(gamete generation)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044339"(canonical Wnt signaling pathway involved in osteoblast differentiation)|go:"GO:0045165"(cell fate commitment)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048697"(positive regulation of collateral sprouting in absence of injury)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060064"(Spemann organizer formation at the anterior end of the primitive streak)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060174"(limb bud formation)|go:"GO:0060323"(head morphogenesis)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0072089"(stem cell proliferation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1905474"(canonical Wnt signaling pathway involved in stem cell proliferation)|interpro:IPR005817(Wnt superfamily)|interpro:IPR009141(Wnt-3 protein)|interpro:IPR018161|interpro:IPR043158|reactome:R-MMU-201681|reactome:R-MMU-3238698	refseq:NP_038851.2|dip:DIP-39894N|ensembl:ENSMUSG00000058488(gene)|ensembl:ENSMUST00000078856(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0004566"(beta-glucuronidase activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR028546|interpro:IPR033132|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190374|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558	-	-	-	figure legend:S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/08/17	2014/10/16	rogid:vP6eVd9KwNAnrQhwXawT3eDoiz410090	rogid:rj/Wc7xYgFTXmP6J9nzgH5rJuhc10090	intact-crc:DA43B546FF52183C|rigid:gabNY7iYJ4FmuL15/WPMsVN5jZU	false	ha tag:?-?	myc tag:c-c	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)