#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8X225 uniprotkb:P07041 intact:EBI-1268994|uniprotkb:Q1K5Y7|ensemblfungi:EAA28243 intact:EBI-1270655|uniprotkb:Q7RV46|uniprotkb:Q8WZD9|ensemblfungi:EAA26767 psi-mi:dim5_neucr(display_long)|uniprotkb:dim-5(gene name)|psi-mi:dim-5(display_short)|uniprotkb:29E8.110(orf name)|uniprotkb:NCU04402(orf name)|uniprotkb:Histone H3-K9 methyltransferase dim-5(gene name synonym) psi-mi:h3_neucr(display_long)|uniprotkb:hh3(gene name)|psi-mi:hh3(display_short)|uniprotkb:B7K22.030(orf name)|uniprotkb:NCU01635(orf name) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2003) pubmed:12887903 taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)") taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1269004|wwpdb:1peg - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_957479.2|dip:DIP-39600N|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|rcsb pdb:1ML9|rcsb pdb:1PEG|ensemblfungi:EAA28243(transcript)|ensemblfungi:NCU04402(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity) refseq:XP_956003.1|dip:DIP-39601N|ensemblfungi:EAA26767(transcript)|ensemblfungi:NCU01635(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0009303"(rRNA transcription)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold) - crc64:2C97AB4B5E582D88 - 3d-r-factors:working 22.0%, free 32.0%|3d-resolution:2.59 A|figure legend:Table 1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/28 2014/10/16 rogid:hDjrnQBwitPm6a2kBoiGxeWXp3k367110 rogid:OxnWKs5/2LKvHlqneAWsdlIbsXU367110 intact-crc:5A7B924CA2076BF3 false - sufficient binding region:2-16 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:16680" uniprotkb:Q8X225 intact:EBI-1180228 intact:EBI-1268994|uniprotkb:Q1K5Y7|ensemblfungi:EAA28243 psi-mi:s-adenosyl-l-homocysteine(display_short)|psi-mi:"CHEBI:16680"(display_long) psi-mi:dim5_neucr(display_long)|uniprotkb:dim-5(gene name)|psi-mi:dim-5(display_short)|uniprotkb:29E8.110(orf name)|uniprotkb:NCU04402(orf name)|uniprotkb:Histone H3-K9 methyltransferase dim-5(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Zhang et al. (2003) pubmed:12887903 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1269004|wwpdb:1peg - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - refseq:XP_957479.2|dip:DIP-39600N|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|rcsb pdb:1ML9|rcsb pdb:1PEG|ensemblfungi:EAA28243(transcript)|ensemblfungi:NCU04402(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity) - - crc64:2C97AB4B5E582D88 3d-r-factors:working 22.0%, free 32.0%|3d-resolution:2.59 A|figure legend:Table 1|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/28 2014/10/16 - rogid:hDjrnQBwitPm6a2kBoiGxeWXp3k367110 intact-crc:5A7B924CA2076BF3 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07041 uniprotkb:Q8X225 intact:EBI-1270655|uniprotkb:Q7RV46|uniprotkb:Q8WZD9|ensemblfungi:EAA26767 intact:EBI-1268994|uniprotkb:Q1K5Y7|ensemblfungi:EAA28243 psi-mi:h3_neucr(display_long)|uniprotkb:hh3(gene name)|psi-mi:hh3(display_short)|uniprotkb:B7K22.030(orf name)|uniprotkb:NCU01635(orf name) psi-mi:dim5_neucr(display_long)|uniprotkb:dim-5(gene name)|psi-mi:dim-5(display_short)|uniprotkb:29E8.110(orf name)|uniprotkb:NCU04402(orf name)|uniprotkb:Histone H3-K9 methyltransferase dim-5(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Zhang et al. (2003) pubmed:12887903 taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)") taxid:367110(neucr)|taxid:367110("Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)") psi-mi:"MI:0414"(enzymatic reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1270225 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_956003.1|dip:DIP-39601N|ensemblfungi:EAA26767(transcript)|ensemblfungi:NCU01635(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0009303"(rRNA transcription)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold) refseq:XP_957479.2|dip:DIP-39600N|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|rcsb pdb:1ML9|rcsb pdb:1PEG|ensemblfungi:EAA28243(transcript)|ensemblfungi:NCU04402(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018024"(histone-lysine N-methyltransferase activity) go:"GO:0042054"(histone methyltransferase activity) - crc64:2C97AB4B5E582D88 figure legend:Figure 2|kinetics:Trimethylated lysine was the main product for all three substrates. Among them, H3 1 to 15 was by far the best substrate, synthesizing trimethylated product 15 to 20 times faster than the other two peptides.|resulting-ptm:Trimethylated peptide|comment:"H3 (1-15) was the best substrate, synthesizing trimethylated product 15 to 20 times faster than the other two peptides studied H3(6-16) and H3(2-14)."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/28 2014/10/16 rogid:OxnWKs5/2LKvHlqneAWsdlIbsXU367110 rogid:hDjrnQBwitPm6a2kBoiGxeWXp3k367110 intact-crc:4BACDCC3970D4728|rigid:rJ+XQ7qVvOFIOmlX8+KjLU7D9x8 false sufficient binding region:2-14 sufficient binding region:30-331 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)