#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43358	uniprotkb:O75832	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385208|imex:IM-19967-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/08/17	2014/10/16	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:7636B96A72231D5F|rigid:LpTYY852l9lKbmq+Yun74hqJLmg	false	sufficient binding region:210-317	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O75832	uniprotkb:P43686	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1388823|imex:IM-19967-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601	-	-	-	caution:The authors state that the C-terminal region of the 26S protease regulatory subunit 6B protein binds to the bait protein , but do not give the coordinates of this region.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/08/17	2014/10/16	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	intact-crc:E1F1A3E491C7C2A2|rigid:DXhScX9q6hSnqb5IeantRjO5It0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P43358	uniprotkb:O75832	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385326|imex:IM-19967-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:1A 4B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/08/17	2014/10/16	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:B442863610B1A77D|rigid:LpTYY852l9lKbmq+Yun74hqJLmg	false	sufficient binding region:307-317	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43358	uniprotkb:O75832	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385362|imex:IM-19967-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2007/08/17	2014/10/16	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:3AEE03A5814CA9F6|rigid:LpTYY852l9lKbmq+Yun74hqJLmg	false	sufficient binding region:210-317|flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43358	uniprotkb:O75832	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385375|imex:IM-19967-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0682"(cofactor)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2007/08/17	2014/10/16	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:838FAE2B5810FE1A|rigid:LpTYY852l9lKbmq+Yun74hqJLmg	false	flag tag:?-?|sufficient binding region:210-317	ha tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43358	uniprotkb:O75832	intact:EBI-743122|ensembl:ENSP00000276344|ensembl:ENSP00000353379|ensembl:ENSP00000359360|ensembl:ENSP00000359365|ensembl:ENSP00000377497|ensembl:ENSP00000377498|ensembl:ENSP00000394149|ensembl:ENSP00000402186|ensembl:ENSP00000506838|ensembl:ENSP00000507023|uniprotkb:Q14798	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:maga4_human(display_long)|uniprotkb:MAGE-4 antigen(gene name synonym)|uniprotkb:MAGE-X2 antigen(gene name synonym)|uniprotkb:MAGE-41 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 1.4(gene name synonym)|uniprotkb:MAGEA4(gene name)|psi-mi:MAGEA4(display_short)|uniprotkb:MAGE4(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385386|imex:IM-19967-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000147381(gene)|ensembl:ENST00000276344(transcript)|ensembl:ENST00000360243(transcript)|ensembl:ENST00000370335(transcript)|ensembl:ENST00000370340(transcript)|ensembl:ENST00000393920(transcript)|ensembl:ENST00000393921(transcript)|ensembl:ENST00000430273(transcript)|ensembl:ENST00000457310(transcript)|ensembl:ENST00000682265(transcript)|ensembl:ENST00000684668(transcript)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045787"(positive regulation of cell cycle)|interpro:IPR002190(MAGE protein)|interpro:IPR021072|interpro:IPR030098|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:P43358|rcsb pdb:1I4F|rcsb pdb:2WA0|rcsb pdb:6TRN|rcsb pdb:6TRO|refseq:NP_001011548.1|refseq:NP_001011549.1|refseq:NP_001011550.1|refseq:NP_002353.3|refseq:XP_005274735.1|refseq:XP_005274736.1	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/08/17	2014/10/16	rogid:wF193QbpesCr14OlGMQD+BabWvs9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:C46625A0F899CA39|rigid:LpTYY852l9lKbmq+Yun74hqJLmg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06400	uniprotkb:O75832	intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym)	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1385407|imex:IM-19967-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	-	-	-	figure legend:3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/08/17	2014/10/16	rogid:xidCNX96KlQzu160polvT61k4Zw9606	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	intact-crc:6B8D36B1D7685F19|rigid:Pu3lyeFl11A3ke1nzBkz3RN+AOc	false	ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O75832	uniprotkb:P43686	intact:EBI-752185|uniprotkb:Q8IZK9|uniprotkb:Q5U0B2|ensembl:ENSP00000217958	intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367	psi-mi:psd10_human(display_long)|uniprotkb:26S proteasome regulatory subunit p28(gene name synonym)|uniprotkb:Gankyrin(gene name synonym)|uniprotkb:PSMD10(gene name)|psi-mi:PSMD10(display_short)|uniprotkb:"p28(GANK)"(gene name synonym)	psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nagao et al. (2003)	pubmed:12525503|imex:IM-19967|mint:MINT-5216032	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1388828|imex:IM-19967-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002805.1|refseq:NP_736606.1|dip:DIP-39026N|ensembl:ENSG00000101843(gene)|ensembl:ENST00000217958(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|mint:O75832|rcsb pdb:1QYM|rcsb pdb:1TR4|rcsb pdb:1UOH|rcsb pdb:4NIK|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|interpro:IPR039334|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8951664	refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601	-	-	-	figure legend:3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/08/17	2014/10/16	rogid:HJ1dl0tNhvWH7pSVWKpadkqe8A09606	rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606	intact-crc:AD7F6CA668499702|rigid:DXhScX9q6hSnqb5IeantRjO5It0	false	flag tag:?-?	enhanced green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)