#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0A817	uniprotkb:P0A817	intact:EBI-546295|uniprotkb:P04384|uniprotkb:P30869|uniprotkb:Q2M9Q1|ensemblbacteria:AAC75979|ensemblbacteria:BAE77005	intact:EBI-546295|uniprotkb:P04384|uniprotkb:P30869|uniprotkb:Q2M9Q1|ensemblbacteria:AAC75979|ensemblbacteria:BAE77005	psi-mi:metk_ecoli(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:metX(gene name synonym)|uniprotkb:b2942(locus name)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:JW2909(locus name)	psi-mi:metk_ecoli(display_long)|uniprotkb:metK(gene name)|psi-mi:metK(display_short)|uniprotkb:metX(gene name synonym)|uniprotkb:b2942(locus name)|uniprotkb:Methionine adenosyltransferase(gene name synonym)|uniprotkb:MAT(gene name synonym)|uniprotkb:JW2909(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Takusagawa et al. (1996)	pubmed:8611562|imex:IM-19090	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1025779|rcsb pdb:1XRA|imex:IM-19090-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0030955"(potassium ion binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042802"(identical protein binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|rcsb pdb:1FUG|rcsb pdb:1MXA|rcsb pdb:1MXB|rcsb pdb:1MXC|rcsb pdb:1P7L|rcsb pdb:1RG9|rcsb pdb:1XRA|go:"GO:0000287"(magnesium ion binding)|rcsb pdb:1XRB|refseq:NP_417417.1|ensemblbacteria:AAC75979(transcript)|ensemblbacteria:b2942(gene)|ensemblbacteria:BAE77005(gene)|refseq:WP_001062128.1|rcsb pdb:1XRC|ensemblbacteria:BAE77005(transcript)|mint:P0A817|dip:DIP-35672N	go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0030955"(potassium ion binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042802"(identical protein binding)|interpro:IPR002133(S-adenosylmethionine synthetase)|interpro:IPR022628|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|rcsb pdb:1FUG|rcsb pdb:1MXA|rcsb pdb:1MXB|rcsb pdb:1MXC|rcsb pdb:1P7L|rcsb pdb:1RG9|rcsb pdb:1XRA|go:"GO:0000287"(magnesium ion binding)|rcsb pdb:1XRB|refseq:NP_417417.1|ensemblbacteria:AAC75979(transcript)|ensemblbacteria:b2942(gene)|ensemblbacteria:BAE77005(gene)|refseq:WP_001062128.1|rcsb pdb:1XRC|ensemblbacteria:BAE77005(transcript)|mint:P0A817|dip:DIP-35672N	-	crc64:97FA8CF17B542941	crc64:97FA8CF17B542941	3d-structure:"MAT consists of four identical subunits. Pairs of subunits (A and B or C and D) strongly interact with each other to form a spherical tight dimer, and these tight dimers associate to a peanut-shaped tetrameric enzyme. The interactions between the tight dimers appear to be much weaker than the subunit-subunit interactions within the tight dimer. Each tight dimer has two active sites located between subunits A and B or C and D, with amino acid residues from both subunits contributing to each active site."|3d-resolution:2.80�|3d-r-factors:working 19.0%, free 25.7%|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/09/20	2014/10/16	rogid:xTQWd11ZyA8UXMUSo7WhlEujgN483333	rogid:xTQWd11ZyA8UXMUSo7WhlEujgN483333	intact-crc:BEFA1BE83E955117|rigid:dkZVOQKtH60wZNCMm15k82vkOOE	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)