#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P19137 uniprotkb:O18738 intact:EBI-7176628|ensembl:ENSMUSP00000043957|intact:MINT-2635122|uniprotkb:F8VQ40 intact:EBI-8522926|intact:MINT-2635114 psi-mi:lama1_mouse(display_long)|uniprotkb:Lama1(gene name)|psi-mi:Lama1(display_short)|uniprotkb:Lama(gene name synonym)|uniprotkb:Lama-1(gene name synonym)|uniprotkb:Laminin A chain(gene name synonym)|uniprotkb:Laminin-1 subunit alpha(gene name synonym)|uniprotkb:Laminin-3 subunit alpha(gene name synonym)|uniprotkb:S-laminin subunit alpha(gene name synonym) psi-mi:dag1_bovin(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:"MI:0049"(filter binding) McDearmon et al. (2006) mint:MINT-5218652|pubmed:16709410|imex:IM-11164 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8522954|mint:MINT-2635160|imex:IM-11164-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032796(gene)|ensembl:ENSMUST00000035471(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0061304"(retinal blood vessel morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:P19137|rcsb pdb:2JD4|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-8874081|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_032506.2|mint:MINT-2635162(identity) interpro:IPR030398|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027468|refseq:NP_776587.1|interpro:IPR015919(Cadherin-like)|mint:O18738|interpro:IPR041631|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0021675"(nerve development)|go:"GO:0042383"(sarcolemma)|go:"GO:0043236"(laminin binding)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|mint:MINT-2635161(identity) - function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components|comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:"Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix"|comment:"Stoichiometry: 1.0" figure legend:F1B|comment:"Alpha-dystroglycan has been prepared from a mix of tissue of different organisms (bovine, rabbit, rat, mouse). Here only an organism has been chosen."|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/22 2018/07/23 rogid:5L6nnYFEE3kmWteC4VtG4c87LHs10090 rogid:5YKucGg3jlNOSDN29om9UY0O3o89913 intact-crc:A8D68214F3C237DA|rigid:1iJFN7U9yX5NMN7oW5SOEfM75H8 false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O18738 uniprotkb:P24043 intact:EBI-8522926|intact:MINT-2635114 intact:EBI-2529730|uniprotkb:Q14736|uniprotkb:Q5VUM2|uniprotkb:Q93022|ensembl:ENSP00000400365 psi-mi:dag1_bovin(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:lama2_human(display_long)|uniprotkb:Laminin-2 subunit alpha(gene name synonym)|uniprotkb:Laminin-4 subunit alpha(gene name synonym)|uniprotkb:Laminin-12 subunit alpha(gene name synonym)|uniprotkb:LAMA2(gene name)|psi-mi:LAMA2(display_short)|uniprotkb:LAMM(gene name synonym)|uniprotkb:Laminin M chain(gene name synonym)|uniprotkb:Merosin heavy chain(gene name synonym) psi-mi:"MI:0049"(filter binding) McDearmon et al. (2006) mint:MINT-5218652|pubmed:16709410|imex:IM-11164 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8522968|mint:MINT-2635197|imex:IM-11164-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030398|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027468|refseq:NP_776587.1|interpro:IPR015919(Cadherin-like)|mint:O18738|interpro:IPR041631|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0021675"(nerve development)|go:"GO:0042383"(sarcolemma)|go:"GO:0043236"(laminin binding)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|mint:MINT-2635198(identity) ensembl:ENSG00000196569(gene)|ensembl:ENST00000421865(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032224"(positive regulation of synaptic transmission, cholinergic)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043197"(dendritic spine)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|mint:P24043|rcsb pdb:4YEP|rcsb pdb:4YEQ|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-8874081|reactome:R-HSA-9619665|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|refseq:NP_000417.2|refseq:NP_001073291.1|dip:DIP-42562N|mint:MINT-2635203(identity) - comment:mint|function:"Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1B|comment:"Alpha-dystroglycan has been prepared from a mix of tissue of different organisms (bovine, rabbit, rat, mouse). Here only an organism has been chosen."|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/22 2014/10/16 rogid:5YKucGg3jlNOSDN29om9UY0O3o89913 rogid:z2F+5o5SCklBK+JoJkvTFZlOgNc9606 intact-crc:B5986724C9FF43EF|rigid:+W50LQDMKGV4P2/hipIj+puSH0M false - - 1 1 psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18738 uniprotkb:O15230 intact:EBI-8522926|intact:MINT-2635114 intact:EBI-725060|uniprotkb:Q8WZA7|uniprotkb:Q9H1P1|uniprotkb:Q8TDF8|uniprotkb:Q5U4N9|ensembl:ENSP00000252999 psi-mi:dag1_bovin(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:lama5_human(display_long)|uniprotkb:LAMA5(gene name)|psi-mi:LAMA5(display_short)|uniprotkb:KIAA0533(gene name synonym)|uniprotkb:KIAA1907(gene name synonym)|uniprotkb:Laminin-10 subunit alpha(gene name synonym)|uniprotkb:Laminin-11 subunit alpha(gene name synonym)|uniprotkb:Laminin-15 subunit alpha(gene name synonym) psi-mi:"MI:0440"(saturation binding) McDearmon et al. (2006) mint:MINT-5218652|pubmed:16709410|imex:IM-11164 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8523019|mint:MINT-2635401|imex:IM-11164-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030398|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027468|refseq:NP_776587.1|interpro:IPR015919(Cadherin-like)|mint:O18738|interpro:IPR041631|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0021675"(nerve development)|go:"GO:0042383"(sarcolemma)|go:"GO:0043236"(laminin binding)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|mint:MINT-2635407(identity) refseq:NP_005551.3|ensembl:ENSG00000130702(gene)|ensembl:ENST00000252999(transcript)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001942"(hair follicle development)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005610"(laminin-5 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016477"(cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030324"(lung development)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0043260"(laminin-11 complex)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0060271"(cilium assembly)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:O15230|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-6785807|reactome:R-HSA-8874081|mint:MINT-2635402(identity) - comment:mint|function:"Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix"|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:"Alpha-dystroglycan has been prepared from a mix of tissue of different organisms (bovine, rabbit, rat, mouse). Here only an organism has been chosen."|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/22 2014/10/16 rogid:5YKucGg3jlNOSDN29om9UY0O3o89913 rogid:rSTl5zwwQKcbd20buKGffFtl3jI9606 intact-crc:B2C0A2EB80672B77|rigid:mfCTf7L9toE5pNC4x7CCs/nGPM0 false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18738 uniprotkb:P19137 intact:EBI-8522926|intact:MINT-2635114 intact:EBI-7176628|ensembl:ENSMUSP00000043957|intact:MINT-2635122|uniprotkb:F8VQ40 psi-mi:dag1_bovin(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:lama1_mouse(display_long)|uniprotkb:Lama1(gene name)|psi-mi:Lama1(display_short)|uniprotkb:Lama(gene name synonym)|uniprotkb:Lama-1(gene name synonym)|uniprotkb:Laminin A chain(gene name synonym)|uniprotkb:Laminin-1 subunit alpha(gene name synonym)|uniprotkb:Laminin-3 subunit alpha(gene name synonym)|uniprotkb:S-laminin subunit alpha(gene name synonym) psi-mi:"MI:0440"(saturation binding) McDearmon et al. (2006) mint:MINT-5218652|pubmed:16709410|imex:IM-11164 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8522992|mint:MINT-2635321|imex:IM-11164-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030398|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027468|refseq:NP_776587.1|interpro:IPR015919(Cadherin-like)|mint:O18738|interpro:IPR041631|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0021675"(nerve development)|go:"GO:0042383"(sarcolemma)|go:"GO:0043236"(laminin binding)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|mint:MINT-2635322(identity) ensembl:ENSMUSG00000032796(gene)|ensembl:ENSMUST00000035471(transcript)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005608"(laminin-3 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0061304"(retinal blood vessel morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|mint:P19137|rcsb pdb:2JD4|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-8874081|go:"GO:0045995"(regulation of embryonic development)|refseq:NP_032506.2|mint:MINT-2635327(identity) - comment:mint|function:"Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix"|comment:"Stoichiometry: 1.0" function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components|comment:mint|comment:"Stoichiometry: 1.0" figure legend:F3A|comment:"Alpha-dystroglycan has been prepared from a mix of tissue of different organisms (bovine, rabbit, rat, mouse). Here only an organism has been chosen."|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/22 2018/07/23 rogid:5YKucGg3jlNOSDN29om9UY0O3o89913 rogid:5L6nnYFEE3kmWteC4VtG4c87LHs10090 intact-crc:C735C2093A485FF7|rigid:1iJFN7U9yX5NMN7oW5SOEfM75H8 false - - 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O18738 uniprotkb:Q16363 intact:EBI-8522926|intact:MINT-2635114 intact:EBI-711505|uniprotkb:Q14731|uniprotkb:Q14735|uniprotkb:Q15335|uniprotkb:Q4LE44|uniprotkb:Q5SZG8|uniprotkb:Q9UE18|uniprotkb:Q9UJN9|uniprotkb:Q9BTB8 psi-mi:dag1_bovin(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:lama4_human(display_long)|uniprotkb:LAMA4(gene name)|psi-mi:LAMA4(display_short)|uniprotkb:Laminin-8 subunit alpha(gene name synonym)|uniprotkb:Laminin-9 subunit alpha(gene name synonym)|uniprotkb:Laminin-14 subunit alpha(gene name synonym) psi-mi:"MI:0440"(saturation binding) McDearmon et al. (2006) mint:MINT-5218652|pubmed:16709410|imex:IM-11164 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8523006|mint:MINT-2635345|imex:IM-11164-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030398|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027468|refseq:NP_776587.1|interpro:IPR015919(Cadherin-like)|mint:O18738|interpro:IPR041631|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007411"(axon guidance)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0021675"(nerve development)|go:"GO:0042383"(sarcolemma)|go:"GO:0043236"(laminin binding)|go:"GO:0045211"(postsynaptic membrane)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|mint:MINT-2635346(identity) interpro:IPR000742(EGF-like, type 3)|refseq:NP_001098678.1|refseq:NP_001098679.1|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR001791(Laminin G)|interpro:IPR009254(Laminin I)|interpro:IPR010307(Laminin II)|refseq:NP_001098676.2|refseq:NP_001098677.2|refseq:NP_002281.3|mint:Q16363|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-8874081|refseq:XP_005267040.2|refseq:XP_005267041.2|mint:MINT-2635351(identity) - comment:mint|function:"Forms part of the dystrophin-associated protein complex (DAPC) which may link the cytoskeleton to the extracellular matrix"|comment:"Stoichiometry: 1.0" - figure legend:F3A|comment:"Alpha-dystroglycan has been prepared from a mix of tissue of different organisms (bovine, rabbit, rat, mouse). Here only an organism has been chosen."|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/06/22 2014/10/16 rogid:5YKucGg3jlNOSDN29om9UY0O3o89913 rogid:oceL+X9xYGdr37L7GlsCO2BMaWQ9606 intact-crc:AC68FC2665AD0304|rigid:XwlGj96ks3BeQf1mTt+MwDEI1gk false - - 1 - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)