#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5WQV5	uniprotkb:Q8BHJ7	intact:EBI-8069271|intact:MINT-1783863	intact:EBI-8069233|intact:MINT-1789015|ensembl:ENSMUSP00000063276|ensembl:ENSMUSP00000145685|ensembl:ENSMUSP00000146238	psi-mi:q5wqv5_rat(display_long)	psi-mi:gbra5_mouse(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069226|mint:MINT-1783882|imex:IM-11127-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1783884(identity)	refseq:NP_795916.1|refseq:XP_006540619.1|refseq:XP_006540620.1|refseq:XP_006540621.1|refseq:XP_006540622.1|refseq:XP_006540623.1|ensembl:ENSMUSG00000055078(gene)|ensembl:ENSMUST00000068456(transcript)|ensembl:ENSMUST00000206382(transcript)|ensembl:ENSMUST00000206734(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008306"(associative learning)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-977443|mint:MINT-1783883(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	figure legend:F1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2006/03/13	2014/10/16	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	rogid:CECv2B3LCLD+cRY1AX3M7pQRuRc10090	intact-crc:5BD4E0A5677AE4DE|rigid:qc2LDD3tPOQPLHJXRYzKaDg7hD0	false	tag:?-?(MINT-1783929)|binding-associated region:89-185(MINT-1783936)	tag:?-?(MINT-1783887)|binding-associated region:342-429(MINT-1783894)	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5WQV5	uniprotkb:P19969	intact:EBI-8069271|intact:MINT-1783863	intact:EBI-8069330|intact:MINT-1783807|ensembl:ENSRNOP00000014573|ensembl:ENSRNOP00000072389|ensembl:ENSRNOP00000076124|ensembl:ENSRNOP00000076137	psi-mi:q5wqv5_rat(display_long)	psi-mi:gbra5_rat(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:Gabra-5(gene name synonym)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069368|mint:MINT-1783951|imex:IM-11127-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1783952(identity)	refseq:XP_017444562.1|refseq:XP_017444563.1|refseq:XP_017444564.1|refseq:XP_017444565.1|refseq:NP_058991.1|rgd:61859|ensembl:ENSRNOG00000010803(gene)|ensembl:ENSRNOT00000014573(transcript)|ensembl:ENSRNOT00000083894(transcript)|ensembl:ENSRNOT00000093259(transcript)|ensembl:ENSRNOT00000093306(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008306"(associative learning)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-RNO-977443|mint:MINT-1783962(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2006/03/13	2014/10/16	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	rogid:TQbHAZPrpZZluV4MgSPtR7wMFak10116	intact-crc:F8D2E3826306A6EA|rigid:p1bPegboN0dJTHoAnD+5rog0SdI	false	-	-	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5WQV5	uniprotkb:Q8BHJ7	intact:EBI-8069271|intact:MINT-1783863	intact:EBI-8069233|intact:MINT-1789015|ensembl:ENSMUSP00000063276|ensembl:ENSMUSP00000145685|ensembl:ENSMUSP00000146238	psi-mi:q5wqv5_rat(display_long)	psi-mi:gbra5_mouse(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069391|mint:MINT-1783984|imex:IM-11127-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1783985(identity)	refseq:NP_795916.1|refseq:XP_006540619.1|refseq:XP_006540620.1|refseq:XP_006540621.1|refseq:XP_006540622.1|refseq:XP_006540623.1|ensembl:ENSMUSG00000055078(gene)|ensembl:ENSMUST00000068456(transcript)|ensembl:ENSMUST00000206382(transcript)|ensembl:ENSMUST00000206734(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008306"(associative learning)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-977443|mint:MINT-1783991(identity)	-	comment:mint|comment:"Stoichiometry: 1.0"	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/13	2014/10/16	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	rogid:CECv2B3LCLD+cRY1AX3M7pQRuRc10090	intact-crc:91AC8F3B3DB96DFA|rigid:qc2LDD3tPOQPLHJXRYzKaDg7hD0	false	-	binding-associated region:342-429(MINT-1784000)|glutathione s tranferase tag:?-?(MINT-1783998)	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q8BHJ7	uniprotkb:Q5WQV5	intact:EBI-8069233|intact:MINT-1789015|ensembl:ENSMUSP00000063276|ensembl:ENSMUSP00000145685|ensembl:ENSMUSP00000146238	intact:EBI-8069271|intact:MINT-1783863	psi-mi:gbra5_mouse(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:q5wqv5_rat(display_long)	psi-mi:"MI:0096"(pull down)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069411|mint:MINT-1784006|imex:IM-11127-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_795916.1|refseq:XP_006540619.1|refseq:XP_006540620.1|refseq:XP_006540621.1|refseq:XP_006540622.1|refseq:XP_006540623.1|ensembl:ENSMUSG00000055078(gene)|ensembl:ENSMUST00000068456(transcript)|ensembl:ENSMUST00000206382(transcript)|ensembl:ENSMUST00000206734(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008306"(associative learning)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-977443|mint:MINT-1784007(identity)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1784016(identity)	-	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F2E|figure legend:F2F|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2006/03/13	2014/10/16	rogid:CECv2B3LCLD+cRY1AX3M7pQRuRc10090	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	intact-crc:328BFB951B7164AB|rigid:qc2LDD3tPOQPLHJXRYzKaDg7hD0	false	binding-associated region:342-429(MINT-1784008)|glutathione s tranferase tag:?-?(MINT-1784014)	mutation increasing interaction:564-564(MINT-1784038)|phosphorylated residue:564-564(MINT-1784036)|myc tag:?-?(MINT-1784034)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P19969	uniprotkb:Q5WQV5	intact:EBI-8069330|intact:MINT-1783807|ensembl:ENSRNOP00000014573|ensembl:ENSRNOP00000072389|ensembl:ENSRNOP00000076124|ensembl:ENSRNOP00000076137	intact:EBI-8069271|intact:MINT-1783863	psi-mi:gbra5_rat(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:Gabra-5(gene name synonym)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:q5wqv5_rat(display_long)	psi-mi:"MI:0428"(imaging technique)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069472|mint:MINT-1784041|imex:IM-11127-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_017444562.1|refseq:XP_017444563.1|refseq:XP_017444564.1|refseq:XP_017444565.1|refseq:NP_058991.1|rgd:61859|ensembl:ENSRNOG00000010803(gene)|ensembl:ENSRNOT00000014573(transcript)|ensembl:ENSRNOT00000083894(transcript)|ensembl:ENSRNOT00000093259(transcript)|ensembl:ENSRNOT00000093306(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008306"(associative learning)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-RNO-977443|mint:MINT-1784054(identity)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1784042(identity)	-	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2006/03/13	2014/10/16	rogid:TQbHAZPrpZZluV4MgSPtR7wMFak10116	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	intact-crc:AF017F04CE477367|rigid:p1bPegboN0dJTHoAnD+5rog0SdI	false	-	-	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)
uniprotkb:Q8BHJ7	uniprotkb:Q5WQV5	intact:EBI-8069233|intact:MINT-1789015|ensembl:ENSMUSP00000063276|ensembl:ENSMUSP00000145685|ensembl:ENSMUSP00000146238	intact:EBI-8069271|intact:MINT-1783863	psi-mi:gbra5_mouse(display_long)|uniprotkb:Gabra5(gene name)|psi-mi:Gabra5(display_short)|uniprotkb:"GABA(A) receptor subunit alpha-5"(gene name synonym)	psi-mi:q5wqv5_rat(display_long)	psi-mi:"MI:0428"(imaging technique)	Loebrich et al. (2006)	pubmed:16467845|imex:IM-11127|mint:MINT-5218325	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8069485|mint:MINT-1784128|imex:IM-11127-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_795916.1|refseq:XP_006540619.1|refseq:XP_006540620.1|refseq:XP_006540621.1|refseq:XP_006540622.1|refseq:XP_006540623.1|ensembl:ENSMUSG00000055078(gene)|ensembl:ENSMUST00000068456(transcript)|ensembl:ENSMUST00000206382(transcript)|ensembl:ENSMUST00000206734(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004890"(GABA-A receptor activity)|go:"GO:0005237"(inhibitory extracellular ligand-gated ion channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008306"(associative learning)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016020"(membrane)|go:"GO:0022851"(GABA-gated chloride ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034707"(chloride channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048666"(neuron development)|go:"GO:0050811"(GABA receptor binding)|go:"GO:0050877"(nervous system process)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060119"(inner ear receptor cell development)|go:"GO:0060384"(innervation)|go:"GO:0090102"(cochlea development)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1902711"(GABA-A receptor complex)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001390(Gamma-aminobutyric-acid A receptor, alpha subunit)|interpro:IPR005435(Gamma-aminobutyric-acid A receptor, alpha 5 subunit)|interpro:IPR006028(Gamma-aminobutyric acid A receptor)|interpro:IPR006029(Neurotransmitter-gated ion-channel transmembrane region)|interpro:IPR006201(Neurotransmitter-gated ion-channel)|interpro:IPR006202(Neurotransmitter-gated ion-channel ligand-binding)|interpro:IPR018000|interpro:IPR036719|interpro:IPR036734|reactome:R-MMU-977443|mint:MINT-1784129(identity)	interpro:IPR019748|interpro:IPR018979|interpro:IPR018980|interpro:IPR008954(Moesin)|interpro:IPR019749|interpro:IPR019747|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR029071|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035963|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0042995"(cell projection)|interpro:IPR041789|mint:MINT-1784135(identity)	-	comment:mint|function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel|comment:"Stoichiometry: 1.0"	comment:mint|comment:"Stoichiometry: 1.0"	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus)	-	2006/03/13	2014/10/16	rogid:CECv2B3LCLD+cRY1AX3M7pQRuRc10090	rogid:+HsiA+wOy6kXzc2Oa0CH6oF+SWs10116	intact-crc:F9915D55A76D02B3|rigid:qc2LDD3tPOQPLHJXRYzKaDg7hD0	false	ha tag:?-?(MINT-1784151)	myc tag:?-?(MINT-1784147)	1	1	psi-mi:"MI:0661"(experimental participant identification)	psi-mi:"MI:0661"(experimental participant identification)