#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q02410 uniprotkb:P49768 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 intact:EBI-297277|ensembl:ENSP00000326366|uniprotkb:O95465|uniprotkb:Q14762|uniprotkb:Q15719|uniprotkb:Q15720|uniprotkb:Q96P33|uniprotkb:Q9UIF0|uniprotkb:B2R6D3 psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:psn1_human(display_long)|uniprotkb:PSEN1(gene name)|psi-mi:PSEN1(display_short)|uniprotkb:AD3(gene name synonym)|uniprotkb:PS1(gene name synonym)|uniprotkb:PSNL1(gene name synonym)|uniprotkb:Protein S182(gene name synonym) psi-mi:"MI:0096"(pull down) Long et al. (2005) pubmed:16007100|mint:MINT-5217828 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7693425|mint:MINT-1889752 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889754(identity) ensembl:ENST00000324501(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000776"(kinetochore)|go:"GO:0001568"(blood vessel development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001756"(somitogenesis)|go:"GO:0001764"(neuron migration)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001947"(heart looping)|go:"GO:0002038"(positive regulation of L-glutamate import across plasma membrane)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0003407"(neural retina development)|go:"GO:0004175"(endopeptidase activity)|ensembl:ENSG00000080815(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006816"(calcium ion transport)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050820"(positive regulation of coagulation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051117"(ATPase binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051563"(smooth endoplasmic reticulum calcium ion homeostasis)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060075"(regulation of resting membrane potential)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904797"(negative regulation of core promoter binding)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001108(Peptidase A22A, presenilin)|interpro:IPR002031(Peptidase A22A, presenilin 1)|interpro:IPR006639(Peptidase A22, presenilin signal peptide)|interpro:IPR042524|mint:P49768|rcsb pdb:2KR6|rcsb pdb:4UIS|rcsb pdb:5A63|rcsb pdb:5FN2|rcsb pdb:5FN3|rcsb pdb:5FN4|rcsb pdb:5FN5|rcsb pdb:6IDF|rcsb pdb:6IYC|rcsb pdb:6LQG|rcsb pdb:6LR4|rcsb pdb:7C9I|rcsb pdb:7D8X|reactome:R-HSA-1251985|reactome:R-HSA-1474228|reactome:R-HSA-193692|reactome:R-HSA-205043|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3928665|reactome:R-HSA-6798695|reactome:R-HSA-9013507|reactome:R-HSA-9013700|reactome:R-HSA-9017802|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0021549"(cerebellum development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021870"(Cajal-Retzius cell differentiation)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0015031"(protein transport)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042500"(aspartic endopeptidase activity, intramembrane cleaving)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048666"(neuron development)|go:"GO:0048705"(skeletal system morphogenesis)|refseq:NP_000012.1|refseq:NP_015557.2|refseq:XP_011535273.1|refseq:XP_011535274.1|refseq:XP_011535275.1|refseq:XP_011535276.1|refseq:XP_005267921.1|refseq:XP_005267923.1|dip:DIP-1134N|mint:MINT-1889753(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/19 2014/10/16 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 rogid:KJwrVRHoYA67u579QC5EZ0Owjoc9606 intact-crc:029C361C8B1C6A71|rigid:0Iwc4HvV25wIzMDB84eicLs+3TA false myc tag:?-?(MINT-1889759) binding-associated region:458-467(MINT-1889772)|glutathione s tranferase tag:?-?(MINT-1889766) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02410 uniprotkb:Q00975 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 intact:EBI-1055161|uniprotkb:B1AQK5|ensembl:ENSP00000360423 psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:cac1b_human(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav2.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide isoform 5(gene name synonym)|uniprotkb:Brain calcium channel III(gene name synonym)|uniprotkb:CACNA1B(gene name)|psi-mi:CACNA1B(display_short)|uniprotkb:CACH5(gene name synonym)|uniprotkb:CACNL1A5(gene name synonym) psi-mi:"MI:0096"(pull down) Long et al. (2005) pubmed:16007100|mint:MINT-5217828 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7693446|mint:MINT-1889775 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889785(identity) refseq:NP_000709.1|refseq:NP_001230741.1|ensembl:ENSG00000148408(gene)|ensembl:ENST00000371372(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045202"(synapse)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070509"(calcium ion import)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005447(Voltage-dependent calcium channel, N-type, alpha-1 subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR043203|rcsb pdb:2LCM|reactome:R-HSA-112308|mint:MINT-1889776(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F6|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2006/04/19 2014/10/16 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 rogid:R7OVT/57HywIdiczIgCa+cjqifA9606 intact-crc:94819FBBF70D065C|rigid:pMWmFiAm9yepqnRZHgf+myOaSd4 false myc tag:?-?(MINT-1889790) glutathione s tranferase tag:?-?(MINT-1889783)|binding-associated region:2331-2339(MINT-1889777) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02410 uniprotkb:Q02410 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Long et al. (2005) pubmed:16007100|mint:MINT-5217828 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7693492|mint:MINT-1889794 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889804(identity) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889795(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2D|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/19 2014/10/16 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 intact-crc:C3EBC1D20BB6AFBE|rigid:JFW7cOCJnkBzZ0nHpwLCAjaT8gs false binding-associated region:655-837(MINT-1889815) binding-associated region:655-747(MINT-1889796) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q02410 uniprotkb:Q02410 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 intact:EBI-368690|uniprotkb:O14914|uniprotkb:O60570|uniprotkb:Q5VYR8|intact:EBI-8840163|intact:EBI-8840293|ensembl:ENSP00000265381 psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:apba1_human(display_long)|uniprotkb:APBA1(gene name)|psi-mi:APBA1(display_short)|uniprotkb:MINT1(gene name synonym)|uniprotkb:X11(gene name synonym)|uniprotkb:Neuron-specific X11 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 1(gene name synonym)|uniprotkb:Adapter protein X11alpha(gene name synonym) psi-mi:"MI:0018"(two hybrid) Long et al. (2005) pubmed:16007100|mint:MINT-5217828 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7693513|mint:MINT-1889840 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889849(identity) refseq:XP_005252025.1|refseq:XP_011516919.1|refseq:NP_001154.2|ensembl:ENST00000265381(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007399"(nervous system development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014051"(gamma-aminobutyric acid secretion)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR030530|interpro:IPR036034|rcsb pdb:1AQC|ensembl:ENSG00000107282(gene)|rcsb pdb:1U37|rcsb pdb:1U38|rcsb pdb:1U39|rcsb pdb:1U3B|rcsb pdb:1X11|rcsb pdb:1X45|rcsb pdb:1Y7N|reactome:R-HSA-212676|reactome:R-HSA-6794361|reactome:R-HSA-9609736|refseq:XP_016870159.1|mint:MINT-1889841(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F2D|comment:homomint|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2006/04/19 2014/10/16 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 rogid:Ntj/7mc+ATzi5O4lwhKsEl920BA9606 intact-crc:3ECB81D564DA1BFC|rigid:JFW7cOCJnkBzZ0nHpwLCAjaT8gs false binding-associated region:655-747(MINT-1889850) binding-associated region:655-837(MINT-1889842) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)