#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450489|mint:MINT-51621 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215876(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215867(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3B|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:07088D8B7AD7708F|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false tag:?-?(MINT-1215877) tag:?-?(MINT-1215871)|binding-associated region:1-101(MINT-1215868) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450556|mint:MINT-51622 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215681(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215689(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:E53253EF682CE668|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false binding-associated region:1-252(MINT-1215682)|tag:?-?(MINT-1215684) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:P70460 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-990384|uniprotkb:Q3UDF1|uniprotkb:Q91VD2|uniprotkb:Q9R214|uniprotkb:Q3TAP0|uniprotkb:Q3TCD2|uniprotkb:Q3U0C2|ensembl:ENSMUSP00000032561 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:vasp_mouse(display_long)|uniprotkb:Vasp(gene name)|psi-mi:Vasp(display_short) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450596|mint:MINT-51624 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215793(identity) ensembl:ENSMUSG00000030403(gene)|ensembl:ENSMUST00000032561(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P70460|rcsb pdb:2V8C|reactome:R-MMU-376176|reactome:R-MMU-446353|refseq:NP_033525.2|refseq:NP_001268950.1|refseq:NP_001268951.1|dip:DIP-29360N|mint:MINT-1215801(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:AgIQZ6LcYTav4f8CrTLmaO9fpo410090 intact-crc:5FF9C75A3C82227D|rigid:lw86P+2DOVlONArkRZ3FKVlAXSE false binding-associated region:398-668(MINT-1215794)|tag:?-?(MINT-1215796) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:P70460 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-990384|uniprotkb:Q3UDF1|uniprotkb:Q91VD2|uniprotkb:Q9R214|uniprotkb:Q3TAP0|uniprotkb:Q3TCD2|uniprotkb:Q3U0C2|ensembl:ENSMUSP00000032561 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:vasp_mouse(display_long)|uniprotkb:Vasp(gene name)|psi-mi:Vasp(display_short) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450576|mint:MINT-51623 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215809(identity) ensembl:ENSMUSG00000030403(gene)|ensembl:ENSMUST00000032561(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P70460|rcsb pdb:2V8C|reactome:R-MMU-376176|reactome:R-MMU-446353|refseq:NP_033525.2|refseq:NP_001268950.1|refseq:NP_001268951.1|dip:DIP-29360N|mint:MINT-1215817(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:AgIQZ6LcYTav4f8CrTLmaO9fpo410090 intact-crc:949A1CBB49D25A7F|rigid:lw86P+2DOVlONArkRZ3FKVlAXSE false tag:?-?(MINT-1215812)|binding-associated region:1-252(MINT-1215810) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450628|mint:MINT-51625 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215886(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215894(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:68D819055D2A6D29|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false binding-associated region:398-668(MINT-1215887)|tag:?-?(MINT-1215889) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450659|mint:MINT-51626 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215774(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215782(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3E|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:D8E07B65120F5844|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false binding-associated region:124-138(MINT-1215775)|tag:?-?(MINT-1215777) binding-associated region:1-108(MINT-1215783) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450700|mint:MINT-51627 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215755(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215763(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3F|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:201FB67F0FD48976|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false binding-associated region:555-570(MINT-1215756)|tag:?-?(MINT-1215758) binding-associated region:1-108(MINT-1215764) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:Q61411 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-400273|uniprotkb:Q80WD2|uniprotkb:Q6P716|uniprotkb:Q811B9|ensembl:ENSMUSP00000026572|ensembl:ENSMUSP00000095570|uniprotkb:F7BIB2 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:rash_mouse(display_long)|uniprotkb:Hras(gene name)|psi-mi:Hras(display_short)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:Hras1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:p21ras(gene name synonym) psi-mi:"MI:0096"(pull down) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450725|mint:MINT-51628 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215902(identity) refseq:NP_001123915.1|refseq:NP_001123916.1|refseq:NP_032310.2|ensembl:ENSMUSG00000025499(gene)|ensembl:ENSMUST00000026572(transcript)|ensembl:ENSMUST00000097957(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:Q61411|rcsb pdb:6KYH|reactome:R-MMU-1169092|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-171007|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-1963640|go:"GO:1900029"(positive regulation of ruffle assembly)|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-375165|reactome:R-MMU-3928662|reactome:R-MMU-5218921|reactome:R-MMU-5621575|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5658442|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-8849471|reactome:R-MMU-8851805|reactome:R-MMU-9607240|reactome:R-MMU-9634635|reactome:R-MMU-9648002|refseq:XP_006536222.2|dip:DIP-29361N|mint:MINT-1215911(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4B|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw10090 intact-crc:3F85510FB1441746|rigid:AZKstx5x/hbTE09UbTIxhPVCZ2s false binding-associated region:151-276(MINT-1215903)|tag:?-?(MINT-1215906) binding-associated region:?-?(MINT-1215912)|tag:?-?(MINT-1215914) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450780|mint:MINT-51618 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215859(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215855(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:homomint|comment:mint taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:6836D511135BC5BA|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false - - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:Q61411 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-400273|uniprotkb:Q80WD2|uniprotkb:Q6P716|uniprotkb:Q811B9|ensembl:ENSMUSP00000026572|ensembl:ENSMUSP00000095570|uniprotkb:F7BIB2 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:rash_mouse(display_long)|uniprotkb:Hras(gene name)|psi-mi:Hras(display_short)|uniprotkb:H-Ras-1(gene name synonym)|uniprotkb:Hras1(gene name synonym)|uniprotkb:Transforming protein p21(gene name synonym)|uniprotkb:c-H-ras(gene name synonym)|uniprotkb:p21ras(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450819|mint:MINT-51629 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215841(identity) refseq:NP_001123915.1|refseq:NP_001123916.1|refseq:NP_032310.2|ensembl:ENSMUSG00000025499(gene)|ensembl:ENSMUST00000026572(transcript)|ensembl:ENSMUST00000097957(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0019003"(GDP binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090398"(cellular senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|mint:Q61411|rcsb pdb:6KYH|reactome:R-MMU-1169092|reactome:R-MMU-1250347|reactome:R-MMU-1433557|reactome:R-MMU-171007|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-1963640|go:"GO:1900029"(positive regulation of ruffle assembly)|reactome:R-MMU-210993|reactome:R-MMU-2179392|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-375165|reactome:R-MMU-3928662|reactome:R-MMU-5218921|reactome:R-MMU-5621575|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5658442|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-8849471|reactome:R-MMU-8851805|reactome:R-MMU-9607240|reactome:R-MMU-9634635|reactome:R-MMU-9648002|refseq:XP_006536222.2|dip:DIP-29361N|mint:MINT-1215845(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4C|comment:mint taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:hjBAnRVG6bLFePkCYnkl3ZCjnmw10090 intact-crc:1AEA1D3A8733DFF5|rigid:AZKstx5x/hbTE09UbTIxhPVCZ2s false - tag:?-?(MINT-1215846) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8R5A3 uniprotkb:P70460 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-990384|uniprotkb:Q3UDF1|uniprotkb:Q91VD2|uniprotkb:Q9R214|uniprotkb:Q3TAP0|uniprotkb:Q3TCD2|uniprotkb:Q3U0C2|ensembl:ENSMUSP00000032561 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:vasp_mouse(display_long)|uniprotkb:Vasp(gene name)|psi-mi:Vasp(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450806|mint:MINT-51620 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215735(identity) ensembl:ENSMUSG00000030403(gene)|ensembl:ENSMUST00000032561(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P70460|rcsb pdb:2V8C|reactome:R-MMU-376176|reactome:R-MMU-446353|refseq:NP_033525.2|refseq:NP_001268950.1|refseq:NP_001268951.1|dip:DIP-29360N|mint:MINT-1215731(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:NFA|comment:homomint|comment:mint taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:AgIQZ6LcYTav4f8CrTLmaO9fpo410090 intact-crc:CCDC82FEA22BB37E|rigid:lw86P+2DOVlONArkRZ3FKVlAXSE false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot) uniprotkb:Q8R5A3 uniprotkb:P32883 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-644267|uniprotkb:P04200|uniprotkb:P08643|ensembl:ENSMUSP00000107339 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:rask_mouse(display_long)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)|uniprotkb:Kras(gene name)|psi-mi:Kras(display_short)|uniprotkb:Kras2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450834|mint:MINT-51630 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215699(identity) refseq:NP_067259.4|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019002"(GMP binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0021897"(forebrain astrocyte development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030275"(LRR domain binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035900"(response to isolation stress)|go:"GO:0038002"(endocrine signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001806(Ras GTPase)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|reactome:R-MMU-2179392|reactome:R-MMU-2424491|interpro:IPR027417|mint:P32883|reactome:R-MMU-1169092|reactome:R-MMU-1250347|reactome:R-MMU-2871796|reactome:R-MMU-375165|reactome:R-MMU-4086398|reactome:R-MMU-1433557|reactome:R-MMU-171007|reactome:R-MMU-179812|reactome:R-MMU-180336|reactome:R-MMU-186763|reactome:R-MMU-1963640|reactome:R-MMU-210993|reactome:R-MMU-5218921|reactome:R-MMU-5621575|reactome:R-MMU-5654688|reactome:R-MMU-5654693|reactome:R-MMU-5654699|reactome:R-MMU-5654700|reactome:R-MMU-5654704|reactome:R-MMU-5654706|reactome:R-MMU-5654712|reactome:R-MMU-5654719|reactome:R-MMU-5658442|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-8849471|reactome:R-MMU-8851805|reactome:R-MMU-8951936|reactome:R-MMU-9607240|reactome:R-MMU-9634635|reactome:R-MMU-9648002|reactome:R-MMU-9674555|ensembl:ENSMUSG00000030265(gene)|ensembl:ENSMUST00000111710(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007565"(female pregnancy)|refseq:XP_006506981.1|dip:DIP-29362N|mint:MINT-1215703(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F4C|comment:mint taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:wRpf3zq2kO/Q0QbC/wp+rJNrBlQ10090 intact-crc:73CDD66B02BAE4E7|rigid:8YyfjzF0RIEkqcDq+vjvnu7kvHk false - tag:?-?(MINT-1215704) - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8R5A3 uniprotkb:Q03173 intact:EBI-7450496|intact:MINT-1215604|uniprotkb:Q8BRU0|uniprotkb:Q99KV8|uniprotkb:O35329|ensembl:ENSMUSP00000014290 intact:EBI-6083294|uniprotkb:P70430|uniprotkb:P70431|uniprotkb:P70432|uniprotkb:P70433|uniprotkb:Q5D053 psi-mi:ab1ip_mouse(display_long)|uniprotkb:Apbb1ip(gene name)|psi-mi:Apbb1ip(display_short)|uniprotkb:Prel1(gene name synonym)|uniprotkb:APBB1-interacting protein 1(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 1(gene name synonym)|uniprotkb:Proline-rich protein 48(gene name synonym) psi-mi:enah_mouse(display_long)|uniprotkb:Enah(gene name)|psi-mi:Enah(display_short)|uniprotkb:Mena(gene name synonym)|uniprotkb:Ndpp1(gene name synonym)|uniprotkb:NPC-derived proline-rich protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jenzora et al. (2005) pubmed:15642358|mint:MINT-5217462 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7450793|mint:MINT-51619 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011237441.1|refseq:NP_062329.2|refseq:XP_006498249.1|ensembl:ENSMUSG00000026786(gene)|ensembl:ENSMUST00000014290(transcript)|go:"GO:0002291"(T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0030027"(lamellipodium)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:3TCA|rcsb pdb:4KVG|rcsb pdb:4W8P|rcsb pdb:6O6H|rcsb pdb:6OLU|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|interpro:IPR000159(Ras-association)|dip:DIP-29358N|mint:MINT-1215747(identity) mint:Q03173|refseq:NP_001076590.1|dip:DIP-29359N|go:"GO:0001725"(stress fiber)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0045202"(synapse)|go:"GO:0050699"(WW domain binding)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR038023|rcsb pdb:1EVH|rcsb pdb:4CC3|reactome:R-MMU-376176|mint:MINT-1215743(identity) - comment:mint|function:Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F3A|comment:homomint|comment:mint taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2005/03/07 2014/10/16 rogid:9jr93w0wAy+3AaySvJ3H7h/Ja2M10090 rogid:MLNC5NL3QIW9Y/aUkc9dTNNAedM10090 intact-crc:44D5FD369C07B705|rigid:kkLg2EikrelCJTXu9BazlAFGdmg false - - - - psi-mi:"MI:0072"(monoclonal antibody western blot) psi-mi:"MI:0072"(monoclonal antibody western blot)