#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92831	uniprotkb:Q8IXJ6	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-477370	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	intact-crc:38E22363BB0E1BAD|rigid:X6D0PhFSZUuT18w7EjT8zfQd+zE	false	flag tag:n-n	binding-associated region:?-?|myc tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q8IXJ6	uniprotkb:Q92831	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-477484	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:EC1844918AA5F0FB|rigid:X6D0PhFSZUuT18w7EjT8zfQd+zE	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q8IXJ6	uniprotkb:Q92830-1	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	intact:EBI-477636|ensembl:ENSP00000225916	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:q92830-1(display_long)|uniprotkb:GCN5-L(isoform synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-477646	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	intact:EBI-477622(gcnl2_human)|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606	intact-crc:795D0BF3AE7F980A|rigid:6hr2AVdr7aXuRHH/SqhhaWb5Unw	false	myc tag:?-?	flag tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q92830-2	uniprotkb:Q8IXJ6	intact:EBI-477641	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	psi-mi:q92830-2(display_long)|uniprotkb:GCN5-S(isoform synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym)	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-477653	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-477622(gcnl2_human)	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:RkQIbCqoK2J3Ia+cz4Y4PigyGfU9606	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	intact-crc:795C5650AE7F6739|rigid:AZ8VCAgC/0kAPJBcwKP56asIGuQ	false	flag tag:n-n	myc tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q8IXJ6	uniprotkb:P15172	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	intact:EBI-488878|uniprotkb:O75321|ensembl:ENSP00000250003	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:myod1_human(display_long)|uniprotkb:Myogenic factor 3(gene name synonym)|uniprotkb:MYOD1(gene name)|psi-mi:MYOD1(display_short)|uniprotkb:MYF3(gene name synonym)|uniprotkb:MYOD(gene name synonym)|uniprotkb:BHLHC1(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-488593	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	refseq:NP_002469.2|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000129152(gene)|ensembl:ENST00000250003(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022032|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|dip:DIP-704N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	rogid:3VTNivTUfx8OwYeE2scVTkN11oY9606	intact-crc:B76BE2F0885949A9|rigid:se2PPFSjX67d34p1+cla42bQmDM	false	myc tag:?-?|binding-associated region:?-?	flag tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q8IXJ6	uniprotkb:Q92831	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-488593	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2005/01/27	2014/10/16	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:B76BE2F0885949A9|rigid:se2PPFSjX67d34p1+cla42bQmDM	false	myc tag:?-?|binding-associated region:?-?	flag tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q92831	uniprotkb:Q8IXJ6	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-477610	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2005/01/27	2014/10/16	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	intact-crc:10A43DE4F65302FB|rigid:X6D0PhFSZUuT18w7EjT8zfQd+zE	false	flag tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P15172	uniprotkb:Q92831	intact:EBI-488878|uniprotkb:O75321|ensembl:ENSP00000250003	intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754	psi-mi:myod1_human(display_long)|uniprotkb:Myogenic factor 3(gene name synonym)|uniprotkb:MYOD1(gene name)|psi-mi:MYOD1(display_short)|uniprotkb:MYF3(gene name synonym)|uniprotkb:MYOD(gene name synonym)|uniprotkb:BHLHC1(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 1(gene name synonym)	psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-489310	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002469.2|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000129152(gene)|ensembl:ENST00000250003(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022032|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|dip:DIP-704N	ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2005/01/27	2014/10/16	rogid:3VTNivTUfx8OwYeE2scVTkN11oY9606	rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606	intact-crc:C579B8755890AA6F|rigid:se2PPFSjX67d34p1+cla42bQmDM	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P15172	uniprotkb:Q8IXJ6	intact:EBI-488878|uniprotkb:O75321|ensembl:ENSP00000250003	intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13	psi-mi:myod1_human(display_long)|uniprotkb:Myogenic factor 3(gene name synonym)|uniprotkb:MYOD1(gene name)|psi-mi:MYOD1(display_short)|uniprotkb:MYF3(gene name synonym)|uniprotkb:MYOD(gene name synonym)|uniprotkb:BHLHC1(gene name synonym)|uniprotkb:Class C basic helix-loop-helix protein 1(gene name synonym)	psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fulco et al. (2003)	pubmed:12887892	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-489310	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002469.2|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007517"(muscle organ development)|go:"GO:0007518"(myoblast fate determination)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007520"(myoblast fusion)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0014904"(myotube cell development)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030016"(myofibril)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043415"(positive regulation of skeletal muscle tissue regeneration)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000129152(gene)|ensembl:ENST00000250003(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000818"(negative regulation of myoblast proliferation)|interpro:IPR002546(Myogenic basic muscle-specific protein)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR022032|interpro:IPR036638|interpro:IPR039704|reactome:R-HSA-525793|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|dip:DIP-704N	ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N	go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0016481"	-	-	-	taxid:9606(human-skeletal-muscle)|taxid:9606(Homo sapiens skeletal muscle.)	-	2005/01/27	2014/10/16	rogid:3VTNivTUfx8OwYeE2scVTkN11oY9606	rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606	intact-crc:C579B8755890AA6F|rigid:se2PPFSjX67d34p1+cla42bQmDM	false	-	binding-associated region:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)