#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q01580	uniprotkb:P00587	intact:EBI-8690603|intact:MINT-1536108|ensembl:ENSSSCP00000015279|ensembl:ENSSSCP00015002232|ensembl:ENSSSCP00025027827|ensembl:ENSSSCP00030020347|ensembl:ENSSSCP00035044010|ensembl:ENSSSCP00040037443|ensembl:ENSSSCP00055005145|ensembl:ENSSSCP00060005558|ensembl:ENSSSCP00065030954|ensembl:ENSSSCP00070000130	intact:EBI-8690588|intact:MINT-1536121	psi-mi:hbegf_pig(display_long)|uniprotkb:HBEGF(gene name)|psi-mi:HBEGF(display_short)|uniprotkb:DTR(gene name synonym)|uniprotkb:HEGFL(gene name synonym)	psi-mi:dtx_corom(display_long)|uniprotkb:"NAD(+)--diphthamide ADP-ribosyltransferase"(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Louie et al. (1997)	mint:MINT-6547973|pubmed:9659904	taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)")	taxid:10714(corom)|taxid:10714(Corynephage omega)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8690583|mint:MINT-24927	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_999464.1|ensembl:ENSSSCG00000014362(gene)|ensembl:ENSSSCG00015004214(gene)|ensembl:ENSSSCG00025047977(gene)|ensembl:ENSSSCG00030032732(gene)|ensembl:ENSSSCG00035075778(gene)|ensembl:ENSSSCG00040062792(gene)|ensembl:ENSSSCG00055003344(gene)|ensembl:ENSSSCG00060010975(gene)|ensembl:ENSSSCG00065051871(gene)|ensembl:ENSSSCG00070000111(gene)|ensembl:ENSSSCT00060014326(transcript)|ensembl:ENSSSCT00065071021(transcript)|ensembl:ENSSSCT00070000161(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|ensembl:ENSSSCT00000015692(transcript)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR015497(Epidermal growth factor receptor ligand)|ensembl:ENSSSCT00015005594(transcript)|ensembl:ENSSSCT00025065260(transcript)|ensembl:ENSSSCT00030045257(transcript)|ensembl:ENSSSCT00035103018(transcript)|ensembl:ENSSSCT00040085561(transcript)|ensembl:ENSSSCT00055006535(transcript)|mint:MINT-1536127(identity)	dip:DIP-370N|interpro:IPR000512("Diphtheria toxin (NAD+-dipthamide ADP-ribosyltransferase)")|interpro:IPR022404|interpro:IPR022405|interpro:IPR022406|interpro:IPR036799|interpro:IPR036801|go:"GO:0005615"(extracellular space)|go:"GO:0047286"(NAD+-diphthamide ADP-ribosyltransferase activity)|go:"GO:0090729"(toxin activity)|mint:MINT-1536134(identity)	-	comment:mint|function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF|comment:"Stoichiometry: 1.0"	comment:mint|function:Diphtheria toxin, produced by a phage infecting corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to elongation factor 2. Fragment A is responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A|comment:"Stoichiometry: 1.0"	comment:In the xray complex 1xdt, Q01580 is chain R and P00587 is chain T Resolution 2.650|comment:mint|dataset:Virus - Publications including interactions involving viral proteins	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:bkxPdMGS17XImcjCmiuABgYKLb89823	rogid:EnLaCFBdr37TXsoj8dRN17O42Yk10714	intact-crc:0B45FE7CB0241212|rigid:9/TTZZ+ElYd9KEvbmkX1fcGLRY8	false	tag:?-?(MINT-1536128)	tag:?-?(MINT-1536135)	1	1	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)