#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0C1Y9 uniprotkb:P21836 intact:EBI-7425928|uniprotkb:P01403|intact:MINT-149065 intact:EBI-7345845|intact:MINT-1206315|ensembl:ENSMUSP00000024099|ensembl:ENSMUSP00000083097 psi-mi:3se1_denan(display_long)|uniprotkb:Fasciculin-I(gene name synonym)|uniprotkb:Toxin TA1(gene name synonym) psi-mi:aces_mouse(display_long)|uniprotkb:Ache(gene name)|psi-mi:Ache(display_short) psi-mi:"MI:0114"(x-ray crystallography) Bourne et al. (1995) mint:MINT-5220849|pubmed:8521480 taxid:8618(denan)|taxid:8618(Dendroaspis angusticeps) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8662883|mint:MINT-24924 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR018354|rcsb pdb:1FAS|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|mint:MINT-1513133(identity) refseq:NP_033729.1|ensembl:ENSMUSG00000023328(gene)|ensembl:ENSMUST00000024099(transcript)|ensembl:ENSMUST00000085934(transcript)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0002076"(osteoblast development)|go:"GO:0003990"(acetylcholinesterase activity)|go:"GO:0004104"(cholinesterase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006581"(acetylcholine catabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007416"(synapse assembly)|go:"GO:0008291"(acetylcholine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017171"(serine hydrolase activity)|go:"GO:0019695"(choline metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0033265"(choline binding)|go:"GO:0042166"(acetylcholine binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043236"(laminin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070997"(neuron death)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000997(Cholinesterase)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR014788(Acetylcholinesterase, tetramerisation)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:P21836|rcsb pdb:1C2B|rcsb pdb:1C2O|rcsb pdb:1J06|rcsb pdb:1J07|rcsb pdb:1KU6|rcsb pdb:1MAA|rcsb pdb:1MAH|rcsb pdb:1N5M|rcsb pdb:1N5R|rcsb pdb:1Q83|rcsb pdb:1Q84|rcsb pdb:2C0P|rcsb pdb:2C0Q|rcsb pdb:2GYU|rcsb pdb:2GYV|rcsb pdb:2GYW|rcsb pdb:2H9Y|rcsb pdb:2HA0|rcsb pdb:2HA2|rcsb pdb:2HA3|rcsb pdb:2HA4|rcsb pdb:2HA5|rcsb pdb:2HA6|rcsb pdb:2HA7|rcsb pdb:2JEY|rcsb pdb:2JEZ|rcsb pdb:2JF0|rcsb pdb:2JGE|rcsb pdb:2JGF|rcsb pdb:2JGI|rcsb pdb:2JGJ|rcsb pdb:2JGL|rcsb pdb:2JGM|rcsb pdb:2WHP|rcsb pdb:2WHQ|rcsb pdb:2WHR|rcsb pdb:2WLS|rcsb pdb:2WU3|rcsb pdb:2WU4|rcsb pdb:2XUD|rcsb pdb:2XUF|rcsb pdb:2XUG|rcsb pdb:2XUH|rcsb pdb:2XUI|rcsb pdb:2XUJ|rcsb pdb:2XUK|rcsb pdb:2XUO|rcsb pdb:2XUP|rcsb pdb:2XUQ|rcsb pdb:2Y2U|rcsb pdb:2Y2V|rcsb pdb:3DL4|rcsb pdb:3DL7|rcsb pdb:3ZLT|rcsb pdb:3ZLU|rcsb pdb:3ZLV|rcsb pdb:4A16|rcsb pdb:4A23|rcsb pdb:4ARA|rcsb pdb:4ARB|rcsb pdb:4B7Z|rcsb pdb:4B80|rcsb pdb:4B81|rcsb pdb:4B82|rcsb pdb:4B83|rcsb pdb:4B84|rcsb pdb:4B85|rcsb pdb:4BC0|rcsb pdb:4BC1|rcsb pdb:4BTL|rcsb pdb:5DTI|rcsb pdb:5DTJ|rcsb pdb:5EHN|rcsb pdb:5EHQ|rcsb pdb:5EHZ|rcsb pdb:5EIA|rcsb pdb:5EIE|rcsb pdb:5EIH|rcsb pdb:5FKJ|rcsb pdb:5FPP|rcsb pdb:5FUM|rcsb pdb:5HCU|rcsb pdb:5OV9|rcsb pdb:6FSD|rcsb pdb:6FSE|rcsb pdb:6TD2|rcsb pdb:2JGK|refseq:NP_001276939.1|mint:MINT-1513126(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft|comment:"Stoichiometry: 1.0" comment:In the xray complex 1mah, P21836 is chain A and P01403 is chain F Resolution 3.200|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:4Y03QoWloLNq/iw+ZwxxbA89NqU8618 rogid:f+Cjyy+U1wBxttirNKyM/PabkNs10090 intact-crc:A28BA3B5728F743E|rigid:pxRSHtTLqhe055Fv6l9+RG3tQQs false tag:?-?(MINT-1513134) tag:?-?(MINT-1513127) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)