#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P46065	uniprotkb:P02638	intact:EBI-6943108|ensembl:ENSBTAP00000057125|intact:MINT-1210679	intact:EBI-458452|ensembl:ENSBTAP00000006275|ensembl:ENSBTAP00000063447|uniprotkb:A4IFR6|uniprotkb:Q3ZBY1	psi-mi:guc1a_bovin(display_long)|uniprotkb:GUCA1A(gene name)|psi-mi:GUCA1A(display_short)|uniprotkb:GCAP1(gene name synonym)|uniprotkb:GUCA1(gene name synonym)|uniprotkb:Guanylate cyclase activator 1A(gene name synonym)	psi-mi:s100b_bovin(display_long)|uniprotkb:S100B(gene name)|psi-mi:S100B(display_short)|uniprotkb:S100 calcium-binding protein B(gene name synonym)|uniprotkb:S-100 protein subunit beta(gene name synonym)|uniprotkb:S-100 protein beta chain(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Duda et al. (2004)	pubmed:15556616|mint:MINT-5217329	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7386225|mint:MINT-50714	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSBTAG00000051956(gene)|ensembl:ENSBTAT00000087322(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0008048"(calcium sensitive guanylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0030249"(guanylate cyclase regulator activity)|go:"GO:0031282"(regulation of guanylate cyclase activity)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0120199"(cone photoreceptor outer segment)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|interpro:IPR033022|mint:P46065|rcsb pdb:2NA0|reactome:R-BTA-2514859|refseq:NP_776971.1|mint:MINT-1210717(identity)	go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0007613"(memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016310"(phosphorylation)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|ensembl:ENSBTAG00000004777(gene)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050786"(RAGE receptor binding)|ensembl:ENSBTAT00000006275(transcript)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|ensembl:ENSBTAT00000086647(transcript)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|rcsb pdb:1PSB|rcsb pdb:3CR2|rcsb pdb:3CR4|rcsb pdb:3CR5|rcsb pdb:3GK1|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|rcsb pdb:3GK2|rcsb pdb:3GK4|rcsb pdb:3IQO|rcsb pdb:3IQQ|rcsb pdb:3LK0|rcsb pdb:3LK1|rcsb pdb:3LLE|rcsb pdb:3RLZ|rcsb pdb:3RM1|rcsb pdb:4FQO|rcsb pdb:4PDZ|rcsb pdb:4PE0|rcsb pdb:4PE1|rcsb pdb:4PE4|rcsb pdb:4PE7|rcsb pdb:5DKN|rcsb pdb:5DKQ|rcsb pdb:5DKR|rcsb pdb:5ER4|rcsb pdb:5ER5|interpro:IPR018247|interpro:IPR028481|rcsb pdb:1CFP|rcsb pdb:1MHO|refseq:NP_001029727.1|mint:MINT-1210721(identity)	-	comment:mint|function:"Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure"|comment:"Stoichiometry: 1.0"	comment:"Stoichiometry: 1.0"	figure legend:F4|comment:homomint|comment:mint	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	-	2004/12/09	2014/10/16	rogid:ObJxTP2SZDw2YXDHzWxt2pp/xJ49913	rogid:vyyQxLdEZgXSBvQWHzKEV/QdO9k9913	intact-crc:EE06C97540B06200|rigid:sFN5nV5IiR+dH5XjjiTtBl5bc+Y	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)