#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q683Z9 uniprotkb:Q9P7T4 intact:EBI-7201241|intact:MINT-1177562 intact:EBI-7201220|ensemblfungi:"SPAC694.06c.1:pep"|intact:MINT-1177572 psi-mi:q683z9_schpm(display_long)|uniprotkb:Cds1(gene name)|psi-mi:Cds1(display_short) psi-mi:mrc1_schpo(display_long)|uniprotkb:mrc1(gene name)|psi-mi:mrc1(display_short)|uniprotkb:SPAC694.06c(orf name)|uniprotkb:DNA replication checkpoint mediator mrc1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tanaka et al. (2004) pubmed:15173168|mint:MINT-5217046 taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7201216|mint:MINT-50564 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR011009(Protein kinase-like)|go:"GO:0016301"(kinase activity)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR000253(Forkhead-associated)|mint:MINT-1177583(identity) go:"GO:0062037"(D-loop DNA binding)|go:"GO:0070337"(3'-flap-structured DNA binding)|go:"GO:0090001"(replication fork arrest at tRNA locus)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:0048478"(replication fork protection)|ensemblfungi:SPAC694.06c(gene)|ensemblfungi:SPAC694.06c.1(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0011000"(replication fork arrest at mating type locus)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031582"(replication fork arrest at rDNA repeats)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0035591"(signaling adaptor activity)|refseq:NP_594486.1|interpro:IPR018564|interpro:IPR024146|reactome:R-SPO-176187|mint:MINT-1177597(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Component of the replisome and is required for rad3-dependent activation of the checkpoint kinase cds1 in response to replication fork arrest. Phosphorylation allows it to mediate the activation of cds1|comment:"Stoichiometry: 1.0" figure legend:F3|comment:mint taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2004/11/25 2014/10/16 rogid:pzb3DFdFWE9rwysDdSAdXYWMcbQ4896 rogid:cu5AwyIBRBrAmMCxQBuHlZP/tKw284812 intact-crc:85C715512640693F|rigid:w3Wm5Jjs/IN6zkpfiDUfZuC5HmI false tag:?-?(MINT-1177592)|mutation decreasing interaction:64-64,78-78,81-81(MINT-1177588)|binding-associated region:1-155(MINT-1177584) tag:?-?(MINT-1177598) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)