#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O60573	uniprotkb:Q13541	intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416	intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691	psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym)	psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tee et al. (2004)	pubmed:15094042	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-398655	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1	refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662	-	-	-	comment:bait is a flag-tagged protein|comment:prey is HA-tagged protein	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2004/08/09	2014/10/16	rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606	rogid:abkjWitYZ9erPSlC88IWI2FtKto9606	intact-crc:16D6797B84329BB2|rigid:FU2wN7aLRtDIg877rzrjPrTepvw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60876	uniprotkb:Q8BMB3	intact:EBI-398674|uniprotkb:Q3TDS8|uniprotkb:Q9CZ40|ensembl:ENSMUSP00000033880	intact:EBI-398682|uniprotkb:O88503|uniprotkb:Q3UCK2|ensembl:ENSMUSP00000108859	psi-mi:4ebp1_mouse(display_long)|uniprotkb:Eif4ebp1(gene name)|psi-mi:Eif4ebp1(display_short)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)	psi-mi:if4e2_mouse(display_long)|uniprotkb:Eif4e2(gene name)|psi-mi:Eif4e2(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:Eif4el3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Tee et al. (2004)	pubmed:15094042	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-398688	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031944.3|dip:DIP-32577N|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|reactome:R-MMU-166208|reactome:R-MMU-72662|ensembl:ENSMUSG00000031490(gene)|ensembl:ENSMUST00000033880(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)	refseq:NP_001034259.1|refseq:NP_075803.2|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:Q8BMB3|reactome:R-MMU-1169408|ensembl:ENSMUSG00000026254(gene)|ensembl:ENSMUST00000113233(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/08/09	2014/10/16	rogid:EYSRK9c019DQ14TAyF1cvmdVll410090	rogid:SgOe+7l/cbYBuu1+sJqsitN0gSM10090	intact-crc:70840A94CF04857B|rigid:xOHtSNgYFxZLHCbzPc8PdnlDINk	false	-	-	-	-	psi-mi:"MI:0093"(protein sequence identification)	psi-mi:"MI:0093"(protein sequence identification)