#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P48598	uniprotkb:O61380	intact:EBI-198574|uniprotkb:Q95SV3|uniprotkb:Q9VSX8|uniprotkb:Q9VSX9|uniprotkb:A4V1Q6|ensemblmetazoa:FBpp0076215|ensemblmetazoa:FBpp0076217|ensemblmetazoa:FBpp0076218|ensemblmetazoa:FBpp0076219|ensemblmetazoa:FBpp0076220|ensemblmetazoa:FBpp0076221|ensemblmetazoa:FBpp0306016|ensemblmetazoa:FBpp0306017	intact:EBI-182219|intact:EBI-389657|uniprotkb:Q7KQ11|ensemblmetazoa:FBpp0088303|ensemblmetazoa:FBpp0288389	psi-mi:if4e_drome(display_long)|uniprotkb:eIF4E1(gene name)|psi-mi:eIF4E1(display_short)|uniprotkb:Eif4e(gene name synonym)|uniprotkb:eIF-4E(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:CG4035(orf name)	psi-mi:o61380_drome(display_long)|uniprotkb:eIF4G1(gene name)|psi-mi:eIF4G1(display_short)|uniprotkb:eIF-4G(gene name synonym)|uniprotkb:eIF4G(gene name synonym)|uniprotkb:eIF4G-RA(gene name synonym)|uniprotkb:Dmel\CG10811(gene name synonym)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:Eif4G(gene name synonym)|uniprotkb:deIF4G(gene name synonym)|uniprotkb:eIF4g(gene name synonym)|uniprotkb:p200(gene name synonym)|uniprotkb:Dmel_CG10811(orf name)|uniprotkb:CG10811(orf name)	psi-mi:"MI:0018"(two hybrid)	Hernandez et al. (2004)	pubmed:14760701	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-389663	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001261626.1|refseq:NP_001261627.1|refseq:NP_524829.1|refseq:NP_729480.1|refseq:NP_729481.1|refseq:NP_729482.1|refseq:NP_729483.1|refseq:NP_729484.1|refseq:NP_729485.1|flybase:FBgn0015218|dip:DIP-17448N|ensemblmetazoa:FBgn0015218(gene)|ensemblmetazoa:FBtr0076487(transcript)|ensemblmetazoa:FBtr0076489(transcript)|ensemblmetazoa:FBtr0076490(transcript)|ensemblmetazoa:FBtr0076491(transcript)|ensemblmetazoa:FBtr0076492(transcript)|ensemblmetazoa:FBtr0076493(transcript)|ensemblmetazoa:FBtr0333884(transcript)|ensemblmetazoa:FBtr0333885(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045182"(translation regulator activity)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097482"(muscle cell postsynaptic specialization)|go:"GO:0098794"(postsynapse)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|rcsb pdb:4AXG|rcsb pdb:4UE8|rcsb pdb:4UE9|rcsb pdb:4UEA|rcsb pdb:4UEB|rcsb pdb:4UEC|rcsb pdb:5ABU|rcsb pdb:5ABV|rcsb pdb:5T47|rcsb pdb:5T48|reactome:R-DME-110523|reactome:R-DME-1169408|reactome:R-DME-156827|reactome:R-DME-159227|reactome:R-DME-159230|reactome:R-DME-159231|reactome:R-DME-166208|reactome:R-DME-429947|reactome:R-DME-72649|reactome:R-DME-72662|reactome:R-DME-72702	refseq:NP_001137857.1|refseq:NP_524640.3|flybase:FBgn0023213|dip:DIP-18880N|ensemblmetazoa:FBgn0023213(gene)|ensemblmetazoa:FBtr0089243(transcript)|ensemblmetazoa:FBtr0289951(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4UEC|rcsb pdb:5T47|rcsb pdb:5T48	-	-	-	comment:interaction is observed between bait region 1 to 259 and prey region 1 to 1024 or 432 to 1666	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/07/21	2014/10/16	rogid:htX4CrNeZ/TE59IjlVxQ9GeQdxk7227	rogid:Hmp5p4wJXpWgNV3cj/xthkJ3G+M7227	intact-crc:366E73EE55326A1A|rigid:ofYMC74gW0cLQFpMNgdw4nQ+x34	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O61380	uniprotkb:Q02748	intact:EBI-182219|intact:EBI-389657|uniprotkb:Q7KQ11|ensemblmetazoa:FBpp0088303|ensemblmetazoa:FBpp0288389	intact:EBI-85570|ensemblmetazoa:FBpp0078806|ensemblmetazoa:FBpp0078807|ensemblmetazoa:FBpp0078808|ensemblmetazoa:FBpp0078809|ensemblmetazoa:FBpp0297911|ensemblmetazoa:FBpp0303628|uniprotkb:A4UZV9|uniprotkb:Q9U9Y6|uniprotkb:Q9VMJ8	psi-mi:o61380_drome(display_long)|uniprotkb:eIF4G1(gene name)|psi-mi:eIF4G1(display_short)|uniprotkb:eIF-4G(gene name synonym)|uniprotkb:eIF4G(gene name synonym)|uniprotkb:eIF4G-RA(gene name synonym)|uniprotkb:Dmel\CG10811(gene name synonym)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:Eif4G(gene name synonym)|uniprotkb:deIF4G(gene name synonym)|uniprotkb:eIF4g(gene name synonym)|uniprotkb:p200(gene name synonym)|uniprotkb:Dmel_CG10811(orf name)|uniprotkb:CG10811(orf name)	psi-mi:if4a_drome(display_long)|uniprotkb:eIF4A(gene name)|psi-mi:eIF4A(display_short)|uniprotkb:ATP-dependent RNA helicase eIF4A(gene name synonym)|uniprotkb:eIF-4a(gene name synonym)|uniprotkb:"l(2L)162"(gene name synonym)|uniprotkb:CG9075(orf name)	psi-mi:"MI:0018"(two hybrid)	Hernandez et al. (2004)	pubmed:14760701	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-389719	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001137857.1|refseq:NP_524640.3|flybase:FBgn0023213|dip:DIP-18880N|ensemblmetazoa:FBgn0023213(gene)|ensemblmetazoa:FBtr0089243(transcript)|ensemblmetazoa:FBtr0289951(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:4UEC|rcsb pdb:5T47|rcsb pdb:5T48	ensemblmetazoa:FBgn0001942(gene)|refseq:NP_001245907.1|ensemblmetazoa:FBtr0079175(transcript)|ensemblmetazoa:FBtr0079176(transcript)|ensemblmetazoa:FBtr0079177(transcript)|ensemblmetazoa:FBtr0079178(transcript)|ensemblmetazoa:FBtr0307068(transcript)|ensemblmetazoa:FBtr0331201(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0007279"(pole cell formation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030718"(germ-line stem cell population maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043186"(P granule)|go:"GO:0046332"(SMAD binding)|go:"GO:0048132"(female germ-line stem cell asymmetric division)|go:"GO:0048477"(oogenesis)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|reactome:R-DME-1169408|reactome:R-DME-156827|reactome:R-DME-429947|reactome:R-DME-72649|reactome:R-DME-72662|reactome:R-DME-72702|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_476595.1|refseq:NP_723137.1|refseq:NP_723138.1|refseq:NP_723139.1|flybase:FBgn0001942|refseq:NP_001260117.1|dip:DIP-18113N	-	-	-	comment:interaction takes place between bait region 432 to 1666 and prey region 1 to 285 or 1 to 148	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/07/21	2014/10/16	rogid:Hmp5p4wJXpWgNV3cj/xthkJ3G+M7227	rogid:UfIeO8H+Hnl325DX4JLZrK/U+Mo7227	intact-crc:96ABE955FBB170E3|rigid:TTQ9wavL0jNjLAh9yTEbAP/tLjo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)