#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O60333 uniprotkb:Q9Y3M8 intact:EBI-465633|uniprotkb:A6NKQ4|uniprotkb:Q4VXC3|uniprotkb:Q96Q94|uniprotkb:Q9BV80|uniprotkb:Q9P280|ensembl:ENSP00000366290|ensembl:ENSP00000502065|uniprotkb:A6NFS8|uniprotkb:Q4VXC5|uniprotkb:Q4VXC6|uniprotkb:Q4VXC4 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 psi-mi:kif1b_human(display_long)|uniprotkb:KIF1B(gene name)|psi-mi:KIF1B(display_short)|uniprotkb:KIAA0591(gene name synonym)|uniprotkb:KIAA1448(gene name synonym) psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465680 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000054523(gene)|ensembl:ENST00000377086(transcript)|ensembl:ENST00000676179(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019821|interpro:IPR022140|interpro:IPR022164|go:"GO:0008017"(microtubule binding)|interpro:IPR027417|interpro:IPR027640|interpro:IPR032405|interpro:IPR036961|rcsb pdb:2EH0|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_055889.2|refseq:NP_904325.2|dip:DIP-33015N refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:2jGqbkJ/vD3mfn//wsfOegvRgio9606 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 intact-crc:A1E25A404CB316EA|rigid:evxEuPbnoBVWCN9s6NGsIL00cxY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86VP1 uniprotkb:Q9Y3M8 intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name) psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649770 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|dip:DIP-33010N|ensembl:ENSG00000106052(gene)|ensembl:ENST00000396319(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0019900"(kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|reactome:R-HSA-5357905|reactome:R-HSA-936440 refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 intact-crc:79F8B01CFB2C2BEC|rigid:J51n4zM7oV3icWdb7c0zB2+ngiA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3M8 uniprotkb:P68363 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649782 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 intact-crc:3C52055379151010|rigid:XZL0nMRndFl6KBbNdoHuCcrhrPo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3M8 uniprotkb:P04035 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 intact:EBI-465513|uniprotkb:B7Z3Y9|uniprotkb:Q8N190|ensembl:ENSP00000287936|ensembl:ENSP00000426745|ensembl:ENSP00000505561|ensembl:ENSP00000505805|ensembl:ENSP00000506232 psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:hmdh_human(display_long)|uniprotkb:HMGCR(gene name)|psi-mi:HMGCR(display_short) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649786 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 refseq:NP_000850.1|refseq:NP_001124468.1|refseq:XP_011541659.1|refseq:XP_011541660.1|ensembl:ENSG00000113161(gene)|ensembl:ENST00000287936(transcript)|ensembl:ENST00000511206(transcript)|ensembl:ENST00000680940(transcript)|ensembl:ENST00000681271(transcript)|ensembl:ENST00000681410(transcript)|go:"GO:0004420"("hydroxymethylglutaryl-CoA reductase (NADPH) activity")|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0006743"(ubiquinone metabolic process)|go:"GO:0007568"(aging)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008299"(isoprenoid biosynthetic process)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070402"(NADPH binding)|go:"GO:0070723"(response to cholesterol)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|interpro:IPR000731(Sterol-sensing 5TM box)|interpro:IPR002202(Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)|interpro:IPR004554(Hydroxymethylglutaryl-CoA reductase, class I, catalytic)|interpro:IPR004816(Hydroxymethylglutaryl-CoA reductase, class I, metazoan)|interpro:IPR009023(Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding)|interpro:IPR009029(Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding)|interpro:IPR023074|interpro:IPR023076|interpro:IPR023282|rcsb pdb:1DQ8|rcsb pdb:1DQ9|rcsb pdb:1DQA|rcsb pdb:1HW8|rcsb pdb:1HW9|rcsb pdb:1HWI|rcsb pdb:1HWJ|rcsb pdb:1HWK|rcsb pdb:1HWL|rcsb pdb:2Q1L|rcsb pdb:2Q6B|rcsb pdb:2Q6C|rcsb pdb:2R4F|rcsb pdb:3BGL|rcsb pdb:3CCT|rcsb pdb:3CCW|rcsb pdb:3CCZ|rcsb pdb:3CD0|rcsb pdb:3CD5|rcsb pdb:3CD7|rcsb pdb:3CDA|rcsb pdb:3CDB|reactome:R-HSA-191273|reactome:R-HSA-1989781|reactome:R-HSA-2426168|reactome:R-HSA-9619665 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 rogid:fXmkDPv7ThH/PSLiNUgYR6hiIpY9606 intact-crc:82F75CB191F2A129|rigid:i0HKbnWl01DGMZwYiYYSWmMk0MM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3M8 uniprotkb:Q9H4G0 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 intact:EBI-465536|uniprotkb:O15046|intact:EBI-28979321|ensembl:ENSP00000337168|uniprotkb:Q4VXM6|uniprotkb:Q4VXM7|uniprotkb:Q4VXM8|uniprotkb:Q4VXN4|uniprotkb:Q6ZT61|uniprotkb:Q8IUU7|uniprotkb:Q96CV5|uniprotkb:Q96L65 psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:e41l1_human(display_long)|uniprotkb:EPB41L1(gene name)|psi-mi:EPB41L1(display_short)|uniprotkb:KIAA0338(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649790 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000338074(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|reactome:R-HSA-399719|ensembl:ENSG00000088367(gene)|refseq:NP_036288.2|refseq:NP_818932.1|ensembl:ENSP00000487049|ensembl:ENST00000202028|ensembl:ENSP00000202028|ensembl:ENSP00000337168|ensembl:ENST00000373950|ensembl:ENSP00000363061|ensembl:ENST00000441639|ensembl:ENSP00000399214|ensembl:ENST00000628415|refseq:NP_001245258.1|refseq:NP_001245259.1|refseq:NP_001245260.1|refseq:XP_016883205.1|refseq:XP_016883206.1|refseq:XP_016883208.1 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 rogid:xjD0lRYDp3hSQcr+y1zYyNN+HBc9606 intact-crc:DE3A5EC55BE194E3|rigid:7V/1KbeyPKPIG7kaFzMrgd4O6uU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q14643 uniprotkb:Q9Y3M8 intact:EBI-465548|ensembl:ENSP00000497605|uniprotkb:Q14660|uniprotkb:Q99897|uniprotkb:E7EPX7|uniprotkb:E9PDE9 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 psi-mi:itpr1_human(display_long)|uniprotkb:ITPR1(gene name)|psi-mi:ITPR1(display_short)|uniprotkb:INSP3R1(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym) psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649793 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000150995(gene)|ensembl:ENST00000649015(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007165"(signal transduction)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|reactome:R-HSA-112043|reactome:R-HSA-114508|reactome:R-HSA-139853|reactome:R-HSA-1489509|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-381676|reactome:R-HSA-4086398|reactome:R-HSA-418457|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695|refseq:NP_001093422.2|refseq:NP_002213.5|refseq:XP_011531985.1|dip:DIP-29714N|refseq:NP_001161744.1 refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:54BRt783vU5D9fCHNO5uFJy1N7I9606 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 intact-crc:F0B95DDBBE6CA2CF|rigid:/UQl+WA5Kc+NCW8WbUeGZXk36kA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3M8 uniprotkb:P08238 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 intact:EBI-352572|ensembl:ENSP00000325875|ensembl:ENSP00000360609|ensembl:ENSP00000360709|ensembl:ENSP00000481908|uniprotkb:Q5T9W7|uniprotkb:Q9NQW0|uniprotkb:Q9NTK6|uniprotkb:B2R5P0 psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:hs90b_human(display_long)|uniprotkb:HSP90AB1(gene name)|psi-mi:HSP90AB1(display_short)|uniprotkb:HSP90B(gene name synonym)|uniprotkb:HSPC2(gene name synonym)|uniprotkb:HSPCB(gene name synonym)|uniprotkb:Heat shock 84 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649797 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 ensembl:ENSG00000096384(gene)|ensembl:ENST00000353801(transcript)|ensembl:ENST00000371554(transcript)|ensembl:ENST00000371646(transcript)|ensembl:ENST00000620073(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_031381.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08238|rcsb pdb:1QZ2|rcsb pdb:1UYM|rcsb pdb:2L6J|rcsb pdb:3FWV|rcsb pdb:3NMQ|rcsb pdb:3PRY|rcsb pdb:3UQ3|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5UC4|rcsb pdb:5UCH|rcsb pdb:5UCI|rcsb pdb:5UCJ|rcsb pdb:6N8W|rcsb pdb:6N8Y|reactome:R-HSA-168928|reactome:R-HSA-2029482|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-399954|reactome:R-HSA-5336415|reactome:R-HSA-6798695|reactome:R-HSA-844456|reactome:R-HSA-8852276|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9660826|reactome:R-HSA-9679191|refseq:NP_001258898.1|refseq:NP_001258899.1|refseq:NP_001258900.1|dip:DIP-413N - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 rogid:wOsW7C10v2oMsM+REE38K6PAan09606 intact-crc:C63F0FFFDBE8F733|rigid:iAsBoByvwybgZG+sEX2Naa9NRHo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Y3M8 uniprotkb:O60241 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 intact:EBI-465623|ensembl:ENSP00000362762|uniprotkb:Q5T6K0|uniprotkb:Q8NGW8|uniprotkb:B9EGK9|uniprotkb:Q96GZ9 psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:agrb2_human(display_long)|uniprotkb:ADGRB2(gene name)|psi-mi:ADGRB2(display_short)|uniprotkb:BAI2(gene name synonym)|uniprotkb:Brain-specific angiogenesis inhibitor 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2649800 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 refseq:NP_001281265.1|ensembl:ENSG00000121753(gene)|ensembl:ENST00000373658(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR008077(GPCR, family 2, brain-specific angiogenesis inhibitor)|interpro:IPR017981|interpro:IPR032471|interpro:IPR036383|interpro:IPR036445|interpro:IPR043838|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|refseq:XP_016857388.1|refseq:XP_016857389.1|refseq:XP_016857394.1|refseq:NP_001281264.1|refseq:XP_011540150.1|refseq:XP_011540151.1 - - - figure legend:Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 rogid:FxNDD5lilxe6W9bd/RXx7ht7HRk9606 intact-crc:74CE8B907979B673|rigid:wkNy76K0BIeyKy8oLn+0WQMSqfM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q86VP1 uniprotkb:Q9Y3M8 intact:EBI-529518|uniprotkb:O60398|uniprotkb:O95770|uniprotkb:Q13311|uniprotkb:Q9BQG5|uniprotkb:Q9UI88|uniprotkb:B4DKU7|uniprotkb:E7ENV2|uniprotkb:A4D196|ensembl:ENSP00000379612 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 psi-mi:taxb1_human(display_long)|uniprotkb:TRAF6-binding protein(gene name synonym)|uniprotkb:TAX1BP1(gene name)|psi-mi:TAX1BP1(display_short)|uniprotkb:T6BP(gene name synonym)|uniprotkb:PRO0105(orf name) psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465693 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073333.1|refseq:NP_001193830.1|refseq:NP_001193831.1|refseq:NP_006015.4|dip:DIP-33010N|ensembl:ENSG00000106052(gene)|ensembl:ENST00000396319(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0019900"(kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q86VP1|rcsb pdb:2M7Q|rcsb pdb:4BMJ|rcsb pdb:4NLH|rcsb pdb:4Z4K|rcsb pdb:4Z4M|rcsb pdb:5AAS|rcsb pdb:5YT6|rcsb pdb:5Z7G|reactome:R-HSA-5357905|reactome:R-HSA-936440 refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:OJfD9nSzpjJ3bMbHugSDVJ9fj/E9606 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 intact-crc:A89687A62C1D0D27|rigid:J51n4zM7oV3icWdb7c0zB2+ngiA false myc tag:?-? v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P68366 uniprotkb:Q9Y3M8 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 intact:EBI-465487|uniprotkb:A2A309|uniprotkb:A2A310|uniprotkb:Q5HYH1|uniprotkb:Q5TAE3|uniprotkb:Q6UN61|uniprotkb:Q86TP6|uniprotkb:Q86WQ3|uniprotkb:Q86XT1|ensembl:ENSP00000338785 psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:sta13_human(display_long)|uniprotkb:START domain-containing protein 13(gene name synonym)|uniprotkb:Deleted in liver cancer 2 protein(gene name synonym)|uniprotkb:Rho GTPase-activating protein(gene name synonym)|uniprotkb:46H23.2(gene name synonym)|uniprotkb:STARD13(gene name)|psi-mi:STARD13(display_short)|uniprotkb:DLC2(gene name synonym)|uniprotkb:GT650(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nagaraja et al. (2004) pubmed:14697242 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-465700 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 refseq:NP_001230395.1|refseq:NP_443083.1|refseq:NP_821074.1|refseq:NP_821075.1|refseq:NP_001230403.1|refseq:NP_001230405.1|ensembl:ENSG00000133121(gene)|ensembl:ENST00000336934(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097498"(endothelial tube lumen extension)|interpro:IPR000198(RhoGAP)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002913(Lipid-binding START)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR023393|rcsb pdb:2H80|rcsb pdb:2JW2|rcsb pdb:2PSO|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/12/06 2014/10/16 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 rogid:xebIB6L+UDTXmMWTBUK8Jvl4ltA9606 intact-crc:BDC9AAB1F494D91E|rigid:OTpPq75bXGG5chQy/Nxq6Gqh3kw false myc tag:?-? v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)