#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7Z3T8	uniprotkb:O60784	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0018"(two hybrid)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298064	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:AA 806-1539 of KIAA0305 is sufficient for its interaction with TOM1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2004/03/04	2014/10/16	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:2D1474A428E338FB|rigid:1+UzhOpXwQJ8z5hzyh4WnENi5T0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z3T8	uniprotkb:O60784	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0096"(pull down)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298073	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:AA 1001-1539 of KIAA0305 and AA 322-353 of TOM1 are sufficient for this interaction. KIAA0305 was Myc tagged.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/03/04	2014/10/16	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:CB9551B3AE254DBB|rigid:1+UzhOpXwQJ8z5hzyh4WnENi5T0	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q7Z3T8	uniprotkb:O60784	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298082	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:Coexpression in 293T cells. KIAA0305 was Myc tagged and TOM1 was Flag tagged. AA 815-1539 of KIAA0305 is sufficient for interaction with TOM1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2004/03/04	2014/10/16	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:0C785D44BC06D7A9|rigid:1+UzhOpXwQJ8z5hzyh4WnENi5T0	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:Q7Z3T8	uniprotkb:O60784	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298094	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:Coexpression in A341 cells. Anti-bait antibody used in the experiment recognized AA 299-492 of TOM1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2004/03/04	2014/10/16	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:78C93E65ABD35F92|rigid:1+UzhOpXwQJ8z5hzyh4WnENi5T0	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q7Z3T8	uniprotkb:O60784	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298110	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:Coexpressed in A431 cells. TOM1 distribution only partially overlaps with that of KIAA0305.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2004/03/04	2014/10/16	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:99A725F0FD36D0DE|rigid:1+UzhOpXwQJ8z5hzyh4WnENi5T0	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q15075	uniprotkb:Q7Z3T8	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298122	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:Coexpressed in A431 cells.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2004/03/04	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606	intact-crc:399749FDAC6A1050|rigid:rhzlQYcxiB1QYpcOAPxn0nxs+5k	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q15075	uniprotkb:O60784	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-74634|intact:EBI-28971074|ensembl:ENSP00000394466|uniprotkb:Q5TIJ6|uniprotkb:B4DEL9|uniprotkb:B4DNA1|uniprotkb:Q86X74	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:tom1_human(display_long)|uniprotkb:TOM1(gene name)|psi-mi:TOM1(display_short)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Seet et al. (2004)	pubmed:14613930	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-298126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	ensembl:ENSG00000100284(gene)|ensembl:ENST00000449058(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030276"(clathrin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002014(VHS)|interpro:IPR004152(GAT)|interpro:IPR008942(ENTH/VHS)|interpro:IPR014645(Target of Myb protein 1)|interpro:IPR038425|mint:O60784|ensembl:ENST00000411850|ensembl:ENSP00000413697|ensembl:ENST00000425375|ensembl:ENSP00000394924|ensembl:ENST00000447733|ensembl:ENSP00000398876|ensembl:ENSP00000394466|refseq:NP_001129201.1|refseq:NP_001129202.1|refseq:NP_001129204.1|refseq:NP_005479.1|rcsb pdb:1ELK|rcsb pdb:1WRD|rcsb pdb:2N2N|rcsb pdb:2N9D|rcsb pdb:6J56|reactome:R-HSA-6798695|dip:DIP-30844N	go:"GO:0005769"(early endosome)|go:"GO:0016197"(endosomal transport)	-	-	comment:Coexpressed in A431 cells. TOM1 distribution only partially overlaps with that of EEA1.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.	taxid:9606(human-a_431)|taxid:9606(Homo sapiens epidermoid carcinoma)	-	2004/03/04	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:MLXfzLA4x1/vwxwbzO5zowzkOtU9606	intact-crc:7148FEC54147607F|rigid:wXtQ/U+Bex3yeTnWzcgRr/NEnMQ	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)