#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61483	uniprotkb:Q9WVQ1	intact:EBI-297125|ensembl:ENSMUSP00000014917|uniprotkb:Q6PFV7	intact:EBI-297151|uniprotkb:Q3UH81|uniprotkb:Q6GT88|ensembl:ENSMUSP00000085872|uniprotkb:Q8BYT1|uniprotkb:Q8CA85	psi-mi:dll1_mouse(display_long)|uniprotkb:Dll1(gene name)|psi-mi:Dll1(display_short)|uniprotkb:Drosophila Delta homolog 1(gene name synonym)	psi-mi:magi2_mouse(display_long)|uniprotkb:Magi2(gene name)|psi-mi:Magi2(display_short)|uniprotkb:Acvrinp1(gene name synonym)|uniprotkb:Arip1(gene name synonym)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Activin receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pfister et al. (2003)	pubmed:14529612	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-297194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014002"(astrocyte development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021688"(cerebellar molecular layer formation)|go:"GO:0021693"(cerebellar Purkinje cell layer structural organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035265"(organ growth)|go:"GO:0040008"(regulation of growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|ensembl:ENSMUSG00000014773(gene)|ensembl:ENSMUST00000014917(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0001947"(heart looping)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007399"(nervous system development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|reactome:R-MMU-9013507|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048630"(skeletal muscle tissue growth)|go:"GO:0048631"(regulation of skeletal muscle tissue growth)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048665"(neuron fate specification)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072006"(nephron development)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097102"(endothelial tip cell fate specification)|go:"GO:0048839"(inner ear development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098773"(skin epidermis development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|refseq:NP_031891.2|dip:DIP-32600N	ensembl:ENSMUSG00000040003(gene)|ensembl:ENSMUST00000088516(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043113"(receptor clustering)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070697"(activin receptor binding)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030036|interpro:IPR036020|interpro:IPR036034|rcsb pdb:6JJZ|rcsb pdb:6KKG|rcsb pdb:7D6F|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|refseq:NP_001164216.1|refseq:NP_001164217.1|refseq:NP_056638.1	-	-	-	comment:"Dll1 is GST tagged.  Residues 738-1113 (IPR001478) of Acvrinp1 and cytoplasmic domain AA 569-722 of Dll1 PDZ-BD were sufficient for interaction."	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/27	2014/10/16	rogid:XF72rbPhGwtIVtvryYqH8opo5Fc10090	rogid:Dj0efnLWnVFm5op5RjDEVBl1NF810090	intact-crc:56D9C46E7A207396|rigid:SR8TOk/FCp2sRIqoXcMZdkvNQec	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61483	uniprotkb:Q9WVQ1	intact:EBI-297125|ensembl:ENSMUSP00000014917|uniprotkb:Q6PFV7	intact:EBI-297151|uniprotkb:Q3UH81|uniprotkb:Q6GT88|ensembl:ENSMUSP00000085872|uniprotkb:Q8BYT1|uniprotkb:Q8CA85	psi-mi:dll1_mouse(display_long)|uniprotkb:Dll1(gene name)|psi-mi:Dll1(display_short)|uniprotkb:Drosophila Delta homolog 1(gene name synonym)	psi-mi:magi2_mouse(display_long)|uniprotkb:Magi2(gene name)|psi-mi:Magi2(display_short)|uniprotkb:Acvrinp1(gene name synonym)|uniprotkb:Arip1(gene name synonym)|uniprotkb:Aip1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 2(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 1(gene name synonym)|uniprotkb:Activin receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Pfister et al. (2003)	pubmed:14529612	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-297190	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0014002"(astrocyte development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021510"(spinal cord development)|go:"GO:0021688"(cerebellar molecular layer formation)|go:"GO:0021693"(cerebellar Purkinje cell layer structural organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0034351"(negative regulation of glial cell apoptotic process)|go:"GO:0035265"(organ growth)|go:"GO:0040008"(regulation of growth)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|ensembl:ENSMUSG00000014773(gene)|ensembl:ENSMUST00000014917(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001757"(somite specification)|go:"GO:0001947"(heart looping)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007399"(nervous system development)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001774("Delta/Serrate/lag-2 (DSL) protein")|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011651(Notch ligand, N-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|reactome:R-MMU-9013507|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048630"(skeletal muscle tissue growth)|go:"GO:0048631"(regulation of skeletal muscle tissue growth)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048665"(neuron fate specification)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060042"(retina morphogenesis in camera-type eye)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072006"(nephron development)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072070"(loop of Henle development)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0097102"(endothelial tip cell fate specification)|go:"GO:0048839"(inner ear development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098773"(skin epidermis development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0051302"(regulation of cell division)|go:"GO:1900746"(regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|refseq:NP_031891.2|dip:DIP-32600N	ensembl:ENSMUSG00000040003(gene)|ensembl:ENSMUST00000088516(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043113"(receptor clustering)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070697"(activin receptor binding)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0098879"(structural constituent of postsynaptic specialization)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030036|interpro:IPR036020|interpro:IPR036034|rcsb pdb:6JJZ|rcsb pdb:6KKG|rcsb pdb:7D6F|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|refseq:NP_001164216.1|refseq:NP_001164217.1|refseq:NP_056638.1	go:"GO:0005515"(protein binding)	-	-	comment:"AA 569-722 of Dll1 used as bait. Prey domains had PDZ4and PDZ5 (IPR001478)."	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2004/02/27	2014/10/16	rogid:XF72rbPhGwtIVtvryYqH8opo5Fc10090	rogid:Dj0efnLWnVFm5op5RjDEVBl1NF810090	intact-crc:F273C8F608679F20|rigid:SR8TOk/FCp2sRIqoXcMZdkvNQec	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)