#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8BH60 uniprotkb:O95196 intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11 intact:EBI-296349|uniprotkb:Q71M39|uniprotkb:Q71M40|ensembl:ENSP00000373244 psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym) psi-mi:cspg5_human(display_long)|uniprotkb:CSPG5(gene name)|psi-mi:CSPG5(display_short)|uniprotkb:Neuroglycan C(gene name synonym)|uniprotkb:Acidic leucine-rich EGF-like domain-containing brain protein(gene name synonym)|uniprotkb:CALEB(gene name synonym)|uniprotkb:NGC(gene name synonym) psi-mi:"MI:0018"(two hybrid) Hassel et al. (2003) pubmed:12885772 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296369 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034 refseq:NP_001193872.1|refseq:NP_001193873.1|refseq:NP_006565.2|ensembl:ENSG00000114646(gene)|ensembl:ENST00000383738(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0040008"(regulation of growth)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0046907"(intracellular transport)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099550"(trans-synaptic signaling, modulating synaptic transmission)|go:"GO:0106091"(glial cell projection elongation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR009505(Neural chondroitin sulphate proteoglycan cytoplasmic)|interpro:IPR010555(Chondroitin sulphate attachment)|interpro:IPR042382|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332 - - - comment:The intracellular domain of O95196 was used as bait. Full length of Q9ET11 found necessary for binding. taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/11 2014/10/16 rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090 rogid:jCdEXy/jGbO8eJWNMbup5sBCf5E9606 intact-crc:628F683488AA2EB5|rigid:SY/ZWKFJIZXLd9lOCPNVs4oLapQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8BH60 uniprotkb:O95196 intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11 intact:EBI-296349|uniprotkb:Q71M39|uniprotkb:Q71M40|ensembl:ENSP00000373244 psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym) psi-mi:cspg5_human(display_long)|uniprotkb:CSPG5(gene name)|psi-mi:CSPG5(display_short)|uniprotkb:Neuroglycan C(gene name synonym)|uniprotkb:Acidic leucine-rich EGF-like domain-containing brain protein(gene name synonym)|uniprotkb:CALEB(gene name synonym)|uniprotkb:NGC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hassel et al. (2003) pubmed:12885772 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296375 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034 refseq:NP_001193872.1|refseq:NP_001193873.1|refseq:NP_006565.2|ensembl:ENSG00000114646(gene)|ensembl:ENST00000383738(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0040008"(regulation of growth)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0046907"(intracellular transport)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099550"(trans-synaptic signaling, modulating synaptic transmission)|go:"GO:0106091"(glial cell projection elongation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR009505(Neural chondroitin sulphate proteoglycan cytoplasmic)|interpro:IPR010555(Chondroitin sulphate attachment)|interpro:IPR042382|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332 - - - comment:Q9ET11 was VSV-tagged. O95196 was FLAG-tagged. Antibodies to VSV tag were used for detection. taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2004/02/11 2014/10/16 rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090 rogid:jCdEXy/jGbO8eJWNMbup5sBCf5E9606 intact-crc:0BFE76E7499677D6|rigid:SY/ZWKFJIZXLd9lOCPNVs4oLapQ false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8BH60 uniprotkb:O95196 intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11 intact:EBI-296349|uniprotkb:Q71M39|uniprotkb:Q71M40|ensembl:ENSP00000373244 psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym) psi-mi:cspg5_human(display_long)|uniprotkb:CSPG5(gene name)|psi-mi:CSPG5(display_short)|uniprotkb:Neuroglycan C(gene name synonym)|uniprotkb:Acidic leucine-rich EGF-like domain-containing brain protein(gene name synonym)|uniprotkb:CALEB(gene name synonym)|uniprotkb:NGC(gene name synonym) psi-mi:"MI:0096"(pull down) Hassel et al. (2003) pubmed:12885772 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296383 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034 refseq:NP_001193872.1|refseq:NP_001193873.1|refseq:NP_006565.2|ensembl:ENSG00000114646(gene)|ensembl:ENST00000383738(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008083"(growth factor activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0040008"(regulation of growth)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0046907"(intracellular transport)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099550"(trans-synaptic signaling, modulating synaptic transmission)|go:"GO:0106091"(glial cell projection elongation)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR009505(Neural chondroitin sulphate proteoglycan cytoplasmic)|interpro:IPR010555(Chondroitin sulphate attachment)|interpro:IPR042382|reactome:R-HSA-1971475|reactome:R-HSA-2022870|reactome:R-HSA-2022923|reactome:R-HSA-2024101|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3595172|reactome:R-HSA-3595174|reactome:R-HSA-3595177|reactome:R-HSA-4420332 - - - comment:Synthetic peptide comprising AA 441-460 of O95196 was used as bait in the pull down. VSV-tagged Q9ET11. taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/11 2014/10/16 rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090 rogid:jCdEXy/jGbO8eJWNMbup5sBCf5E9606 intact-crc:5A0F0A30D08ECDE8|rigid:SY/ZWKFJIZXLd9lOCPNVs4oLapQ false - binding-associated region:441-460 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9DF69 uniprotkb:Q8BH60 intact:EBI-296418|uniprotkb:O13003 intact:EBI-296357|uniprotkb:Q8BSV4|uniprotkb:Q920R1|uniprotkb:Q9ET11 psi-mi:cspg5_chick(display_long)|uniprotkb:CSPG5(gene name)|psi-mi:CSPG5(display_short)|uniprotkb:Acidic leucine-rich EGF-like domain-containing brain protein(gene name synonym)|uniprotkb:CALEB(gene name synonym) psi-mi:gopc_mouse(display_long)|uniprotkb:Gopc(gene name)|psi-mi:Gopc(display_short)|uniprotkb:PDZ protein interacting specifically with TC10(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Hassel et al. (2003) pubmed:12885772 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-296429 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR010555(Chondroitin sulphate attachment)|interpro:IPR009505(Neural chondroitin sulphate proteoglycan cytoplasmic)|refseq:NP_990050.1|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045202"(synapse)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0099550"(trans-synaptic signaling, modulating synaptic transmission)|go:"GO:0040008"(regulation of growth)|interpro:IPR042382 go:"GO:0000139"(Golgi membrane)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010360"(negative regulation of anion channel activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043004"(cytoplasmic sequestering of CFTR protein)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|reactome:R-MMU-5627083|reactome:R-MMU-9013406|refseq:NP_001186201.1|refseq:NP_444417.2|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR038879|mint:Q8BH60|interpro:IPR036034 go:"GO:0005794"(Golgi apparatus)|go:"GO:0046907"(intracellular transport) - - comment:Visualised in COS7 cells using FLAG and VSV antibodies. taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2004/02/11 2014/10/16 rogid:huDTajichsbXrWP5FzZ9/vRV70U9031 rogid:g5t7Tcg8R/HEVPryIgPE21/mCsA10090 intact-crc:61C6AEF1D4723B89|rigid:N5EPrgSmeYcgBSLTY5okbKQXSAQ false flag tag:?-? tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)