#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P62155	uniprotkb:P40136	intact:EBI-397568|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q6INP3	intact:EBI-457011|uniprotkb:Q937W4|uniprotkb:Q937W5|ensemblbacteria:AAT28883	psi-mi:calm_xenla(display_long)|uniprotkb:calm1(gene name)|psi-mi:calm1(display_short)|uniprotkb:calm2(gene name)|psi-mi:calm2(display_short)	psi-mi:cyaa_bacan(display_long)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:Anthrax edema toxin adenylate cyclase component(gene name synonym)|uniprotkb:Edema factor(gene name synonym)|uniprotkb:cya(gene name)|psi-mi:cya(display_short)|uniprotkb:pXO1-122(locus name)|uniprotkb:BXA0141(locus name)|uniprotkb:GBAA_pXO1_0142(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ulmer et al. (2003)	pubmed:12724328	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:1392(bacan)|taxid:1392(Bacillus anthracis)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-457125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:1DMO|rcsb pdb:1F70|rcsb pdb:1F71|go:"GO:0005509"(calcium ion binding)|refseq:NP_001080864.1|refseq:NP_001084025.1|refseq:NP_001089059.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1CFC|rcsb pdb:1CFD|rcsb pdb:1CFF|rcsb pdb:1CKK|rcsb pdb:1IQ5|rcsb pdb:1MUX|rcsb pdb:1NWD|rcsb pdb:1SY9|rcsb pdb:1X02|rcsb pdb:1Y0V|rcsb pdb:2COL|rcsb pdb:2K3S|rcsb pdb:2KDU|rcsb pdb:2RRT|rcsb pdb:4R8G|rcsb pdb:5T0X|rcsb pdb:2MES|refseq:XP_018085904.1|go:"GO:0005102"(signaling receptor binding)	refseq:NP_052818.1|refseq:WP_000197748.1|ensemblbacteria:AAT28883(transcript)|ensemblbacteria:GBAA_pXO1_0142(gene)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008294"(calcium- and calmodulin-responsive adenylate cyclase activity)|go:"GO:0044164"(host cell cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0090729"(toxin activity)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:1902494"(catalytic complex)|interpro:IPR003541(Anthrax toxin, lethal/endema factor, N-terminal)|interpro:IPR005165(Anthrax toxin, edema factor, central)|interpro:IPR014781(Anthrax toxin, lethal/endema factor, N- and C-terminal)|interpro:IPR024079|interpro:IPR035099|interpro:IPR037017|rcsb pdb:1K8T|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1LVC|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1XFU|reactome:R-HSA-5210891|dip:DIP-31055N|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y0V|rcsb pdb:6UZB|rcsb pdb:6UZD|rcsb pdb:6UZE|rcsb pdb:6VRA	-	-	-	-	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/11/09	2014/10/16	rogid:tTYcOd9bOh211njZVz7cYVybAMQ8355	rogid:O+KTrZ8wXLCal3KJmyi0HJv4Soc1392	intact-crc:6633D65B6FEC3B71|rigid:8YBg9v/Vq45ugbXIqTDsrNIHuYk	false	-	sufficient binding region:291-800	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)