#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61823 uniprotkb:Q61655 intact:EBI-296473|uniprotkb:P97296|uniprotkb:Q3T9A9|ensembl:ENSMUSP00000025931|ensembl:ENSMUSP00000073975|ensembl:ENSMUSP00000133135 intact:EBI-296479|ensembl:ENSMUSP00000047898|uniprotkb:Q921R0|uniprotkb:Q543M2 psi-mi:pdcd4_mouse(display_long)|uniprotkb:Pdcd4(gene name)|psi-mi:Pdcd4(display_short)|uniprotkb:Ma3(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed protein(gene name synonym)|uniprotkb:Protein MA-3(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:dd19a_mouse(display_long)|uniprotkb:Ddx19a(gene name)|psi-mi:Ddx19a(display_short)|uniprotkb:Eif4a-rs1(gene name synonym)|uniprotkb:DEAD box protein 19A(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD5(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4A-related sequence 1(gene name synonym)|uniprotkb:Ddx19(gene name synonym) psi-mi:"MI:0115"(yeast display) Yang et al. (2003) pubmed:12482958 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-296488 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|ensembl:ENSMUSG00000024975(gene)|ensembl:ENSMUST00000025931(transcript)|ensembl:ENSMUST00000074371(transcript)|ensembl:ENSMUST00000165617(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|mint:Q61823|rcsb pdb:2HM8|rcsb pdb:2IOL|rcsb pdb:2ION|rcsb pdb:2IOS|rcsb pdb:2KZT|rcsb pdb:2NSZ|rcsb pdb:3EIQ|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|refseq:NP_001161963.1|refseq:NP_001161964.1|refseq:NP_035180.2|refseq:XP_006526825.1 ensembl:ENSMUSG00000015023(gene)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|ensembl:ENSMUST00000040416(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|refseq:NP_031942.2 - - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/02/15 2014/10/16 rogid:ruEZtMgfVyIslPFdsTmuOfZhwuM10090 rogid:CRGSz3D04vAZhTcXG/jhMHfe1lQ10090 intact-crc:FF0A65D56A9CBDB1|rigid:r+bBiZ2dR4oIhADttu1LjrGpzt0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q61823 uniprotkb:Q62448 intact:EBI-296473|uniprotkb:P97296|uniprotkb:Q3T9A9|ensembl:ENSMUSP00000025931|ensembl:ENSMUSP00000073975|ensembl:ENSMUSP00000133135 intact:EBI-296494|uniprotkb:P97867|uniprotkb:Q0VGZ3|uniprotkb:Q3UNC1|uniprotkb:Q5XKD8|uniprotkb:Q6P1Z0|uniprotkb:Q921U3 psi-mi:pdcd4_mouse(display_long)|uniprotkb:Pdcd4(gene name)|psi-mi:Pdcd4(display_short)|uniprotkb:Ma3(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed protein(gene name synonym)|uniprotkb:Protein MA-3(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:if4g2_mouse(display_long)|uniprotkb:Eif4g2(gene name)|psi-mi:Eif4g2(display_short)|uniprotkb:Nat1(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Novel APOBEC-1 target 1(gene name synonym)|uniprotkb:Translation repressor NAT1(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2003) pubmed:12482958 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|ensembl:ENSMUSG00000024975(gene)|ensembl:ENSMUST00000025931(transcript)|ensembl:ENSMUST00000074371(transcript)|ensembl:ENSMUST00000165617(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|mint:Q61823|rcsb pdb:2HM8|rcsb pdb:2IOL|rcsb pdb:2ION|rcsb pdb:2IOS|rcsb pdb:2KZT|rcsb pdb:2NSZ|rcsb pdb:3EIQ|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|refseq:NP_001161963.1|refseq:NP_001161964.1|refseq:NP_035180.2|refseq:XP_006526825.1 go:"GO:0030424"(axon)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0060999"(positive regulation of dendritic spine development)|reactome:R-MMU-1169408|go:"GO:0034645"(cellular macromolecule biosynthetic process)|refseq:NP_001035221.1|refseq:NP_038535.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|mint:Q62448 pubmed:12482958(primary-reference) - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:10090(mouse)|taxid:10090(Mus musculus) - 2004/02/15 2014/10/16 rogid:ruEZtMgfVyIslPFdsTmuOfZhwuM10090 rogid:Mv7bkccswjA/XXuUQFVSD550aO010090 intact-crc:02B00484224E9863|rigid:xd4opDJX33FIjMh2UgpTzuqL54g false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:Q61823 uniprotkb:Q62448 intact:EBI-296473|uniprotkb:P97296|uniprotkb:Q3T9A9|ensembl:ENSMUSP00000025931|ensembl:ENSMUSP00000073975|ensembl:ENSMUSP00000133135 intact:EBI-296494|uniprotkb:P97867|uniprotkb:Q0VGZ3|uniprotkb:Q3UNC1|uniprotkb:Q5XKD8|uniprotkb:Q6P1Z0|uniprotkb:Q921U3 psi-mi:pdcd4_mouse(display_long)|uniprotkb:Pdcd4(gene name)|psi-mi:Pdcd4(display_short)|uniprotkb:Ma3(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed protein(gene name synonym)|uniprotkb:Protein MA-3(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:if4g2_mouse(display_long)|uniprotkb:Eif4g2(gene name)|psi-mi:Eif4g2(display_short)|uniprotkb:Nat1(gene name synonym)|uniprotkb:p97(gene name synonym)|uniprotkb:Novel APOBEC-1 target 1(gene name synonym)|uniprotkb:Translation repressor NAT1(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2003) pubmed:12482958 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-296513 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007569"(cell aging)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0060940"(epithelial to mesenchymal transition involved in cardiac fibroblast development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:1905064"(negative regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|ensembl:ENSMUSG00000024975(gene)|ensembl:ENSMUST00000025931(transcript)|ensembl:ENSMUST00000074371(transcript)|ensembl:ENSMUST00000165617(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039778|mint:Q61823|rcsb pdb:2HM8|rcsb pdb:2IOL|rcsb pdb:2ION|rcsb pdb:2IOS|rcsb pdb:2KZT|rcsb pdb:2NSZ|rcsb pdb:3EIQ|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|refseq:NP_001161963.1|refseq:NP_001161964.1|refseq:NP_035180.2|refseq:XP_006526825.1 go:"GO:0030424"(axon)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0060999"(positive regulation of dendritic spine development)|reactome:R-MMU-1169408|go:"GO:0034645"(cellular macromolecule biosynthetic process)|refseq:NP_001035221.1|refseq:NP_038535.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR016021(MIF4-like, type 1/2/3)|mint:Q62448 pubmed:12482958(primary-reference) - - dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:10090(mouse)|taxid:10090(Mus musculus) - 2004/02/15 2014/10/16 rogid:ruEZtMgfVyIslPFdsTmuOfZhwuM10090 rogid:Mv7bkccswjA/XXuUQFVSD550aO010090 intact-crc:08861441B429AB94|rigid:xd4opDJX33FIjMh2UgpTzuqL54g false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)