#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8R4E9 uniprotkb:Q60862 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 intact:EBI-457142|ensembl:ENSMUSP00000027198 psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:orc2_mouse(display_long)|uniprotkb:Orc2(gene name)|psi-mi:Orc2(display_short)|uniprotkb:Orc2l(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yanagi et al. (2002) pubmed:12192004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-457131 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) refseq:NP_032791.1|ensembl:ENSMUSG00000026037(gene)|ensembl:ENSMUST00000027198(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000808"(origin recognition complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005813"(centrosome)|go:"GO:0006260"(DNA replication)|interpro:IPR007220(Origin recognition complex subunit 2)|reactome:R-MMU-176187|reactome:R-MMU-68616|reactome:R-MMU-68689|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|refseq:NP_001258455.1 - - - comment:Weak interaction taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/11/09 2014/10/16 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 rogid:mG5foO+hpAPT/3BIw9jDTSVR5p010090 intact-crc:28777816EE7CA975|rigid:V72H15nQKtJ9Ojpruqe6pS4saHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97311 uniprotkb:Q8R4E9 intact:EBI-457132|uniprotkb:Q80YQ7|ensembl:ENSMUSP00000027601 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 psi-mi:mcm6_mouse(display_long)|uniprotkb:Mis5 homolog(gene name synonym)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:Mcmd6(gene name synonym)|uniprotkb:Mis5(gene name synonym) psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yanagi et al. (2002) pubmed:12192004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-457154 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032593.1|ensembl:ENSMUSG00000026355(gene)|ensembl:ENSMUST00000027601(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|mint:P97311|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052 refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/11/09 2014/10/16 rogid:JwuQj25XyutAyROxAkOr/NyIjCA10090 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 intact-crc:15E827CBF4FE9F89|rigid:WHWI7ZCmGm6f/P0YsXBF0YKSPAk false - binding-associated region:335-557 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88513 uniprotkb:Q8R4E9 intact:EBI-445922|ensembl:ENSMUSP00000006898|ensembl:ENSMUSP00000106011 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 psi-mi:gemi_mouse(display_long)|uniprotkb:Gmnn(gene name)|psi-mi:Gmnn(display_short) psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yanagi et al. (2002) pubmed:12192004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-457161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065592.1|refseq:XP_006516786.1|dip:DIP-32562N|ensembl:ENSMUSG00000006715(gene)|ensembl:ENSMUST00000006898(transcript)|ensembl:ENSMUST00000110382(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000104"(negative regulation of DNA-dependent DNA replication)|interpro:IPR022786|interpro:IPR029697|reactome:R-MMU-68827|reactome:R-MMU-68962|rcsb pdb:2ZXX refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2004/11/09 2014/10/16 rogid:FnezPIg7tsn2yJ4U6vb01AIZOfs10090 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 intact-crc:40427E28476C4EB4|rigid:V3lEerxyL+sE2bvbiQhQ0XbFtYg false - binding-associated region:172-288 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P97311 uniprotkb:Q8R4E9 intact:EBI-457132|uniprotkb:Q80YQ7|ensembl:ENSMUSP00000027601 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 psi-mi:mcm6_mouse(display_long)|uniprotkb:Mis5 homolog(gene name synonym)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:Mcmd6(gene name synonym)|uniprotkb:Mis5(gene name synonym) psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:"MI:0096"(pull down) Yanagi et al. (2002) pubmed:12192004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-457189 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032593.1|ensembl:ENSMUSG00000026355(gene)|ensembl:ENSMUST00000027601(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|mint:P97311|reactome:R-MMU-176187|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|reactome:R-MMU-69052 refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0005656"(nuclear pre-replicative complex) - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/09 2014/10/16 rogid:JwuQj25XyutAyROxAkOr/NyIjCA10090 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 intact-crc:A127BA109AF1F681|rigid:WHWI7ZCmGm6f/P0YsXBF0YKSPAk false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8R4E9 uniprotkb:O88513 intact:EBI-457043|uniprotkb:Q8BUQ1|uniprotkb:Q8BX29|uniprotkb:Q8R3V0|uniprotkb:Q8R4E8|ensembl:ENSMUSP00000006760 intact:EBI-445922|ensembl:ENSMUSP00000006898|ensembl:ENSMUSP00000106011 psi-mi:cdt1_mouse(display_long)|uniprotkb:Double parked homolog(gene name synonym)|uniprotkb:Retroviral insertion site 2 protein(gene name synonym)|uniprotkb:Cdt1(gene name)|psi-mi:Cdt1(display_short)|uniprotkb:Ris2(gene name synonym) psi-mi:gemi_mouse(display_long)|uniprotkb:Gmnn(gene name)|psi-mi:Gmnn(display_short) psi-mi:"MI:0096"(pull down) Yanagi et al. (2002) pubmed:12192004 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-457195 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080290.3|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045740"(positive regulation of DNA replication)|ensembl:ENSMUSG00000006585(gene)|ensembl:ENSMUST00000006760(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016604"(nuclear body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0033262"(regulation of nuclear cell cycle DNA replication)|interpro:IPR032054|interpro:IPR036390|interpro:IPR038090|rcsb pdb:2KLO|rcsb pdb:2RQQ|rcsb pdb:2ZXX|rcsb pdb:3A4C|reactome:R-MMU-68827|reactome:R-MMU-68867|reactome:R-MMU-68949|reactome:R-MMU-68962|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0072708"(response to sorbitol)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1905341"(negative regulation of protein localization to kinetochore)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|go:"GO:2000105"(positive regulation of DNA-dependent DNA replication)|interpro:IPR014939(DNA replication factor CDT1-like) refseq:NP_065592.1|refseq:XP_006516786.1|dip:DIP-32562N|ensembl:ENSMUSG00000006715(gene)|ensembl:ENSMUST00000006898(transcript)|ensembl:ENSMUST00000110382(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000104"(negative regulation of DNA-dependent DNA replication)|interpro:IPR022786|interpro:IPR029697|reactome:R-MMU-68827|reactome:R-MMU-68962|rcsb pdb:2ZXX go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0005656"(nuclear pre-replicative complex) - - - taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/09 2014/10/16 rogid:GkxXG8geC2JHCrw2tNWQzIhf+W410090 rogid:FnezPIg7tsn2yJ4U6vb01AIZOfs10090 intact-crc:6EB161F8793DB37F|rigid:V3lEerxyL+sE2bvbiQhQ0XbFtYg false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)