#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13053 uniprotkb:P11473 intact:EBI-8309660|intact:MINT-236433 intact:EBI-286357|uniprotkb:Q5PSV3|uniprotkb:B2R5Q1|uniprotkb:G3V1V9|ensembl:ENSP00000378734|ensembl:ENSP00000449573 psi-mi:vdr_rat(display_long)|uniprotkb:Vdr(gene name)|psi-mi:Vdr(display_short)|uniprotkb:Nr1i1(gene name synonym)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym) psi-mi:vdr_human(display_long)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym)|uniprotkb:VDR(gene name)|psi-mi:VDR(display_short)|uniprotkb:NR1I1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Shaffer et al. (2002) pubmed:11980721|mint:MINT-5215339 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8309727|mint:MINT-24841 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:5XPL|rcsb pdb:5XPM|rcsb pdb:5XPO|rcsb pdb:5XPP|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0032355"(response to estradiol)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0008285"(negative regulation of cell population proliferation)|rcsb pdb:4YNK|rcsb pdb:3WTQ|rcsb pdb:5B5B|rcsb pdb:5H1E|rcsb pdb:5B41|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:1RKH|rcsb pdb:3AFR|rcsb pdb:2ZXM|rcsb pdb:2ZMH|rcsb pdb:2ZLC|rcsb pdb:3VT5|rcsb pdb:2ZMJ|rcsb pdb:3VTD|rcsb pdb:3VJT|rcsb pdb:3VT8|rcsb pdb:3VT3|rcsb pdb:1RKG|rcsb pdb:2O4J|rcsb pdb:1RJK|rgd:3959|rcsb pdb:3AUN|rcsb pdb:3VRU|interpro:IPR013088(Zinc finger, NHR/GATA-type)|rcsb pdb:3VT4|refseq:NP_058754.1|rcsb pdb:3VT7|rcsb pdb:2ZMI|rcsb pdb:3VRT|rcsb pdb:3VTB|rcsb pdb:3A2H|rcsb pdb:2O4R|rcsb pdb:2ZLA|rcsb pdb:1RK3|rcsb pdb:3VTC|rcsb pdb:2ZL9|rcsb pdb:2ZXN|rcsb pdb:3VT6|rcsb pdb:3VRV|rcsb pdb:2ZFX|rcsb pdb:3VRW|rcsb pdb:3VT9|rcsb pdb:3VJS|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:5AWJ|rcsb pdb:5AWK|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR035500|interpro:IPR042153|rcsb pdb:5XUQ|rcsb pdb:5XPN|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|reactome:R-RNO-196791|reactome:R-RNO-383280|reactome:R-RNO-4090294|rcsb pdb:6K5O|rcsb pdb:6JEZ|rcsb pdb:7C7V|rcsb pdb:7C7W|mint:MINT-714527(identity) refseq:NP_000367.1|refseq:NP_001017535.1|refseq:NP_001017536.1|refseq:XP_006719650.1|refseq:XP_011537022.1|dip:DIP-32624N|ensembl:ENSG00000111424(gene)|ensembl:ENST00000395324(transcript)|ensembl:ENST00000549336(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P11473|rcsb pdb:1DB1|rcsb pdb:1IE8|rcsb pdb:1IE9|rcsb pdb:1KB2|rcsb pdb:1KB4|rcsb pdb:1KB6|rcsb pdb:1S0Z|rcsb pdb:1S19|rcsb pdb:1TXI|rcsb pdb:1YNW|rcsb pdb:2HAM|rcsb pdb:2HAR|rcsb pdb:2HAS|rcsb pdb:2HB7|rcsb pdb:2HB8|rcsb pdb:3A2I|rcsb pdb:3A2J|rcsb pdb:3A3Z|rcsb pdb:3A40|rcsb pdb:3A78|rcsb pdb:3AUQ|rcsb pdb:3AUR|rcsb pdb:3AX8|rcsb pdb:3AZ1|rcsb pdb:3AZ2|rcsb pdb:3AZ3|rcsb pdb:3B0T|rcsb pdb:3CS4|rcsb pdb:3CS6|rcsb pdb:3KPZ|rcsb pdb:3M7R|rcsb pdb:3OGT|rcsb pdb:3P8X|rcsb pdb:3TKC|rcsb pdb:3VHW|rcsb pdb:3W0A|rcsb pdb:3W0C|rcsb pdb:3W0Y|rcsb pdb:3WGP|rcsb pdb:3WWR|rcsb pdb:3X31|rcsb pdb:3X36|rcsb pdb:4G2I|rcsb pdb:4ITE|rcsb pdb:4ITF|rcsb pdb:5GT4|rcsb pdb:5V39|rcsb pdb:5YSY|rcsb pdb:5YT2|reactome:R-HSA-196791|reactome:R-HSA-383280|reactome:R-HSA-4090294|mint:MINT-714520(identity) - comment:mint|function:Nuclear hormone receptor. VDR mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:In the xray complex 1kb2, P11473 is chain A and P13053 is chain B Resolution 2.700|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:rlHu12bw3TEnTXDNmuSXW+w553c10116 rogid:7j3KKs/nPSWIKLnb2SZqA+UAysM9606 intact-crc:2C6B3053FE5AC658|rigid:H5chFcXDiIrnCNUAtajQdke7+y0 false tag:?-?(MINT-714528) tag:?-?(MINT-714521) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)