#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00763 uniprotkb:P14754 intact:EBI-1029166|ensembl:ENSRNOP00000018853 intact:EBI-1032177 psi-mi:try2_rat(display_long)|uniprotkb:Prss2(gene name)|psi-mi:Prss2(display_short)|uniprotkb:Try2(gene name synonym)|uniprotkb:Anionic trypsin II(gene name synonym)|uniprotkb:Pretrypsinogen II(gene name synonym)|uniprotkb:Serine protease 2(gene name synonym) psi-mi:sera_manse(display_long)|uniprotkb:Serpin-1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Ye et al. (2001) pubmed:11685246|mint:MINT-5214742 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:7130(manse)|taxid:7130("Manduca sexta (Tobacco hawkmoth)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-1032191|rcsb pdb:1K9O - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3418|refseq:NP_036861.1|ensembl:ENSRNOG00000032916(gene)|ensembl:ENSRNOT00000018852(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007584"(response to nutrient)|go:"GO:0007586"(digestion)|go:"GO:0030574"(collagen catabolic process)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:1AMH|rcsb pdb:1ANB|rcsb pdb:1ANC|rcsb pdb:1AND|rcsb pdb:1ANE|rcsb pdb:1BRA|rcsb pdb:1BRB|rcsb pdb:1BRC|rcsb pdb:1CO7|rcsb pdb:1DPO|rcsb pdb:1EZS|rcsb pdb:1EZU|rcsb pdb:1F5R|rcsb pdb:1F7Z|rcsb pdb:1FY8|rcsb pdb:1J14|rcsb pdb:1J15|rcsb pdb:1J16|rcsb pdb:1J17|rcsb pdb:1K9O|rcsb pdb:1QL9|rcsb pdb:1SLU|rcsb pdb:1SLV|rcsb pdb:1SLW|rcsb pdb:1SLX|rcsb pdb:1TRM|rcsb pdb:1YKT|rcsb pdb:1YLC|rcsb pdb:1YLD|rcsb pdb:2TRM|rcsb pdb:3FP6|rcsb pdb:3FP7|rcsb pdb:3FP8|rcsb pdb:3TGI|rcsb pdb:3TGJ|rcsb pdb:3TGK|reactome:R-RNO-1462054|reactome:R-RNO-1592389|reactome:R-RNO-196741|reactome:R-RNO-6798695|reactome:R-RNO-6803157|dip:DIP-6112N interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|rcsb pdb:1K9O|rcsb pdb:1SEK|interpro:IPR042178|interpro:IPR042185|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0009617"(response to bacterium)|interpro:IPR036186|interpro:IPR015557(Protease inhibitor I4, serpin B1) - - - assembly:dimeric, multimeric|3d-r-factors:working 84.200%, free 76.900%|3d-resolution:2.3A|dataset:PDBe - Data obtained from the Protein Data Bank Europe taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:pd1mQna5A30w4eYG7/ryILU/IFw10116 rogid:Iqp7B7vF9kL2w/r3ks9T13QdiwY7130 intact-crc:795DCF726EC7E137|rigid:4C0iXitVwLSaArcVOOXMBHDJ6RI false sufficient binding region:24-246 sufficient binding region:15-392 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)