#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q03023 uniprotkb:Q03026 intact:EBI-7901485|intact:MINT-204154|ensemblbacteria:AAG04638 intact:EBI-7901529|intact:MINT-204143|ensemblbacteria:AAG04639 psi-mi:apra_pseae(display_long)|uniprotkb:Alkaline metalloproteinase(gene name synonym)|uniprotkb:PA1249(locus name)|uniprotkb:aprA(gene name)|psi-mi:aprA(display_short) psi-mi:inh_pseae(display_long)|uniprotkb:inh(gene name)|psi-mi:inh(display_short)|uniprotkb:aprI(gene name synonym)|uniprotkb:PA1250(locus name)|uniprotkb:Aprin(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Hege et al. (2001) pubmed:11445573|mint:MINT-5214251 taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") taxid:208964(pseae)|taxid:208964("Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7901547|mint:MINT-24922 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_003082542.1|interpro:IPR016294(Peptidase M10B)|interpro:IPR011049(Serralysin-like metalloprotease, C-terminal)|rcsb pdb:1AKL|rcsb pdb:1JIW|interpro:IPR018511|rcsb pdb:1KAP|interpro:IPR013858(Peptidase M10, serralysin, C-terminal)|refseq:NP_249940.1|interpro:IPR024079|rcsb pdb:3VI1|ensemblbacteria:AAG04638(transcript)|ensemblbacteria:PA1249(gene)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0045959"(negative regulation of complement activation, classical pathway)|interpro:IPR034033|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR001343(Haemolysin-type calcium-binding region)|mint:MINT-580849(identity) refseq:WP_003082543.1|rcsb pdb:2RN4|interpro:IPR021140|interpro:IPR016085(Protease inhibitor, beta-barrel)|refseq:NP_249941.1|rcsb pdb:1JIW|interpro:IPR022815|ensemblbacteria:AAG04639(transcript)|ensemblbacteria:PA1250(gene)|go:"GO:0008191"(metalloendopeptidase inhibitor activity)|go:"GO:0042597"(periplasmic space)|mint:MINT-580842(identity) - comment:mint|comment:"Stoichiometry: 1.0" comment:mint|function:Inhibitor of the alkaline protease. It forms a non-covalent bond with the protease and may prevent its autocatalytic cleavage in the periplasm|comment:"Stoichiometry: 1.0" comment:In the xray complex 1jiw, Q03026 is chain I and Q03023 is chain P Resolution 1.740|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/02/12 2014/10/16 rogid:p0oVgbLtSG2HjRmVq38VL5yCLj0208964 rogid:C9cAVXEZ6tHeil4h/93xO6G4l4I208964 intact-crc:9F89C698DFADD57B|rigid:PVcKgm929wiPpM9spyuW7Hny4mM false tag:?-?(MINT-580850) tag:?-?(MINT-580843) 1 1 psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)