#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P40381 uniprotkb:P09988 intact:EBI-926939|ensemblfungi:"SPAC664.01c.1:pep" intact:EBI-2112358|ensemblfungi:"SPAC1834.04.1:pep"|ensemblfungi:"SPBC1105.11c.1:pep"|ensemblfungi:"SPBC8D2.04.1:pep" psi-mi:swi6_schpo(display_long)|uniprotkb:swi6(gene name)|psi-mi:swi6(display_short)|uniprotkb:SPAC664.01c(orf name)|uniprotkb:SPAC824.10c(orf name) psi-mi:h31_schpo(display_long)|uniprotkb:hht1(gene name)|psi-mi:hht1(display_short)|uniprotkb:hht2(gene name)|psi-mi:hht2(display_short)|uniprotkb:SPAC1834.04(orf name)|uniprotkb:SPBC8D2.04(orf name)|uniprotkb:pi060(orf name) psi-mi:"MI:0096"(pull down) Bannister et al. (2001) pubmed:11242054|mint:MINT-5213686 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7793971|mint:MINT-50476 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_593449.1|dip:DIP-35736N|reactome:R-SPO-73772|reactome:R-SPO-983231|ensemblfungi:SPAC664.01c(gene)|ensemblfungi:SPAC664.01c.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006325"(chromatin organization)|go:"GO:0007533"(mating type switching)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0033696"(heterochromatin boundary formation)|go:"GO:0034507"(chromosome, centromeric outer repeat region)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044820"(mitotic telomere tethering at nuclear periphery)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0090053"(positive regulation of pericentric heterochromatin assembly)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1990342"(heterochromatin island)|go:"GO:1990758"(mitotic sister chromatid biorientation)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|rcsb pdb:1E0B|rcsb pdb:2RSO|mint:MINT-1571295(identity) refseq:NP_594683.1|refseq:NP_595567.1|refseq:NP_596467.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000164(Histone H3)|rcsb pdb:2DZE|rcsb pdb:3G7L|ensemblfungi:SPAC1834.04(gene)|ensemblfungi:SPAC1834.04.1(transcript)|ensemblfungi:SPBC1105.11c(gene)|ensemblfungi:SPBC1105.11c.1(transcript)|ensemblfungi:SPBC8D2.04(gene)|ensemblfungi:SPBC8D2.04.1(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031454"|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:1904361"(positive regulation of spore germination)|mint:MINT-1571303(identity) - crc64:F505CC8AC5E75EAB|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/11 2014/10/16 rogid:EEISpq3oLJ9jyNp6870DB1Z3xCY284812 rogid:sgVGFQktZdVWD8pWmmorFgeOkRE284812 intact-crc:F2DAB8A9C2D3CDD2|rigid:dkMFOa4XP9eVesFr65PABNSnreM false binding-associated region:80-133(MINT-1571296)|tag:?-?(MINT-1571298) N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1571306)|binding-associated region:1-16(MINT-1571304) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0083"(peptide synthesis) intact:EBI-1179609 uniprotkb:P83917 - intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475 psi-mi:h3_peptide-4(display_short)|psi-mi:EBI-1179609(display_long) psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym) psi-mi:"MI:0096"(pull down) Bannister et al. (2001) pubmed:11242054|mint:MINT-5213686 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7794076|mint:MINT-50498 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) uniprotkb:P68433(see-also)|uniprotkb:Q71DI3(see-also)|mint:MINT-1619525(identity) ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N|mint:MINT-1619516(identity) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/11 2014/10/16 rogid:OmIsae0Sg/lBwfokPJEMHCPOfzI-2 rogid:W2npW/vFRcuTkStKpknsAP69q6I10090 intact-crc:FE72E6C4F58585A8|rigid:GTg78a+N4KmI/iuMXv1lMAZVW0k false N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1619530)|binding-associated region:1-16(MINT-1619526)|N6,N6,N6-trimethyl-L-lysine:4-4(MINT-1619528) mutation decreasing interaction:41-41,42-42(MINT-1619517)|tag:?-?(MINT-1619520) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) intact:EBI-1179609 uniprotkb:P83917 - intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475 psi-mi:h3_peptide-4(display_short)|psi-mi:EBI-1179609(display_long) psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym) psi-mi:"MI:0096"(pull down) Bannister et al. (2001) pubmed:11242054|mint:MINT-5213686 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7794120|mint:MINT-50499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) uniprotkb:P68433(see-also)|uniprotkb:Q71DI3(see-also)|mint:MINT-1573167(identity) ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N|mint:MINT-1573159(identity) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/11 2014/10/16 rogid:OmIsae0Sg/lBwfokPJEMHCPOfzI-2 rogid:W2npW/vFRcuTkStKpknsAP69q6I10090 intact-crc:D534CA47F9C5178C|rigid:GTg78a+N4KmI/iuMXv1lMAZVW0k false binding-associated region:1-16(MINT-1573168)|N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1573172)|N6,N6,N6-trimethyl-L-lysine:4-4(MINT-1573170) mutation decreasing interaction:23-23(MINT-1573160)|tag:?-?(MINT-1573162) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0113"(western blot) uniprotkb:P83917 intact:EBI-1179609 intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475 - psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym) psi-mi:h3_peptide-4(display_short)|psi-mi:EBI-1179609(display_long) psi-mi:"MI:0096"(pull down) Bannister et al. (2001) pubmed:11242054|mint:MINT-5213686 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7794189|mint:MINT-50500 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N|mint:MINT-1713845(identity) uniprotkb:P68433(see-also)|uniprotkb:Q71DI3(see-also)|mint:MINT-1713851(identity) - comment:"Stoichiometry: 1.0" no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/11 2014/10/16 rogid:W2npW/vFRcuTkStKpknsAP69q6I10090 rogid:OmIsae0Sg/lBwfokPJEMHCPOfzI-2 intact-crc:ABB963490C5BFA2F|rigid:GTg78a+N4KmI/iuMXv1lMAZVW0k false tag:?-?(MINT-1713846) N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1713852) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0363"(inferred by author) uniprotkb:P83917 intact:EBI-1179609 intact:EBI-78119|uniprotkb:P23197|ensembl:ENSMUSP00000091475 - psi-mi:cbx1_mouse(display_long)|uniprotkb:Cbx1(gene name)|psi-mi:Cbx1(display_short)|uniprotkb:Cbx(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym) psi-mi:h3_peptide-4(display_short)|psi-mi:EBI-1179609(display_long) psi-mi:"MI:0013"(biophysical) Bannister et al. (2001) pubmed:11242054|mint:MINT-5213686 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7794240|mint:MINT-50497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) ensembl:ENSMUSG00000018666(gene)|ensembl:ENSMUST00000093943(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83917|rcsb pdb:1AP0|rcsb pdb:1DZ1|rcsb pdb:1GUW|rcsb pdb:1S4Z|refseq:NP_031648.1|refseq:XP_006532162.1|refseq:XP_006532163.1|refseq:XP_011247006.1|refseq:XP_017169731.1|dip:DIP-30892N|mint:MINT-1710023(identity) uniprotkb:P68433(see-also)|uniprotkb:Q71DI3(see-also)|mint:MINT-1710031(identity) - comment:"Stoichiometry: 1.0" no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:"Stoichiometry: 1.0" kd:70 nanomolar|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/11/11 2014/10/16 rogid:W2npW/vFRcuTkStKpknsAP69q6I10090 rogid:OmIsae0Sg/lBwfokPJEMHCPOfzI-2 intact-crc:2A23436BC4078016|rigid:GTg78a+N4KmI/iuMXv1lMAZVW0k false binding-associated region:10-80(MINT-1710024)|tag:?-?(MINT-1710026) N6,N6,N6-trimethyl-L-lysine:4-4(MINT-1710034)|binding-associated region:1-16(MINT-1710032)|N6,N6,N6-trimethyl-L-lysine:9-9(MINT-1710036) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0083"(peptide synthesis)