#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P54322	uniprotkb:P56968	intact:EBI-1030598|uniprotkb:A2RK90|ensemblbacteria:CAL97700	intact:EBI-1030589|uniprotkb:A2RK89|ensemblbacteria:CAL97699	psi-mi:pyrdb_laclm(display_long)|uniprotkb:pyrDB(gene name)|psi-mi:pyrDB(display_short)|uniprotkb:"Orotate reductase (NADH)"(gene name synonym)|uniprotkb:llmg_1106(locus name)|uniprotkb:Dihydroorotate oxidase B(gene name synonym)	psi-mi:pyrk_laclm(display_long)|uniprotkb:pyrK(gene name)|psi-mi:pyrK(display_short)|uniprotkb:llmg_1105(locus name)|uniprotkb:Dihydroorotate oxidase B, electron transfer subunit(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Rowland et al. (2000)	pubmed:11188687|mint:MINT-5213538	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1030612|rcsb pdb:1EP1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|interpro:IPR024920|ensemblbacteria:CAL97700(transcript)|ensemblbacteria:llmg_1106(gene)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0004589"("orotate reductase (NADH) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|refseq:WP_011835014.1|interpro:IPR033888	interpro:IPR012165(Cytochrome-c3 hydrogenase, gamma subunit)|interpro:IPR019480|interpro:IPR017927|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR000951(Phthalate dioxygenase reductase, FPNCR module)|interpro:IPR017938|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|ensemblbacteria:CAL97699(transcript)|ensemblbacteria:llmg_1105(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009055"(electron transfer activity)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR023455|refseq:WP_011835013.1|interpro:IPR039261|interpro:IPR037117	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 79.800%, free 74.400%|3d-resolution:2.2A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:LPFgr/BepSPUJS5rdL0TVgpdnO0416870	rogid:V4TuH2Eo05cOdgzNXKxSUSVnO8E416870	intact-crc:DA5DE11845E19599|rigid:fpWtXtx8iYntdsiSV8R2WJyBeHo	false	sufficient binding region:1-311	sufficient binding region:2-262	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P56968	uniprotkb:P54322	intact:EBI-1030589|uniprotkb:A2RK89|ensemblbacteria:CAL97699	intact:EBI-1030598|uniprotkb:A2RK90|ensemblbacteria:CAL97700	psi-mi:pyrk_laclm(display_long)|uniprotkb:pyrK(gene name)|psi-mi:pyrK(display_short)|uniprotkb:llmg_1105(locus name)|uniprotkb:Dihydroorotate oxidase B, electron transfer subunit(gene name synonym)	psi-mi:pyrdb_laclm(display_long)|uniprotkb:pyrDB(gene name)|psi-mi:pyrDB(display_short)|uniprotkb:"Orotate reductase (NADH)"(gene name synonym)|uniprotkb:llmg_1106(locus name)|uniprotkb:Dihydroorotate oxidase B(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Rowland et al. (2000)	pubmed:11188687|mint:MINT-5213538	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1030623|rcsb pdb:1EP2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR012165(Cytochrome-c3 hydrogenase, gamma subunit)|interpro:IPR019480|interpro:IPR017927|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR000951(Phthalate dioxygenase reductase, FPNCR module)|interpro:IPR017938|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|ensemblbacteria:CAL97699(transcript)|ensemblbacteria:llmg_1105(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009055"(electron transfer activity)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR023455|refseq:WP_011835013.1|interpro:IPR039261|interpro:IPR037117	interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|interpro:IPR024920|ensemblbacteria:CAL97700(transcript)|ensemblbacteria:llmg_1106(gene)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0004589"("orotate reductase (NADH) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|refseq:WP_011835014.1|interpro:IPR033888	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 81.00%, free 75.900%|3d-resolution:2.4A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:V4TuH2Eo05cOdgzNXKxSUSVnO8E416870	rogid:LPFgr/BepSPUJS5rdL0TVgpdnO0416870	intact-crc:97112D66DC294A59|rigid:fpWtXtx8iYntdsiSV8R2WJyBeHo	false	sufficient binding region:2-262	sufficient binding region:1-311	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54322	uniprotkb:P56968	intact:EBI-1030598|uniprotkb:A2RK90|ensemblbacteria:CAL97700	intact:EBI-1030589|uniprotkb:A2RK89|ensemblbacteria:CAL97699	psi-mi:pyrdb_laclm(display_long)|uniprotkb:pyrDB(gene name)|psi-mi:pyrDB(display_short)|uniprotkb:"Orotate reductase (NADH)"(gene name synonym)|uniprotkb:llmg_1106(locus name)|uniprotkb:Dihydroorotate oxidase B(gene name synonym)	psi-mi:pyrk_laclm(display_long)|uniprotkb:pyrK(gene name)|psi-mi:pyrK(display_short)|uniprotkb:llmg_1105(locus name)|uniprotkb:Dihydroorotate oxidase B, electron transfer subunit(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Rowland et al. (2000)	pubmed:11188687|mint:MINT-5213538	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	taxid:416870(laclm)|taxid:416870("Lactococcus lactis subsp. cremoris (strain MG1363)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-1030634|rcsb pdb:1EP3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR005720(Dihydroorotate dehydrogenase, class 1, core)|interpro:IPR012135(Dihydroorotate dehydrogenase, classes 1 and 2)|interpro:IPR001295(Dihydroorotate dehydrogenase, core)|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|interpro:IPR024920|ensemblbacteria:CAL97700(transcript)|ensemblbacteria:llmg_1106(gene)|go:"GO:0004152"(dihydroorotate dehydrogenase activity)|go:"GO:0004589"("orotate reductase (NADH) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0044205"('de novo' UMP biosynthetic process)|refseq:WP_011835014.1|interpro:IPR033888	interpro:IPR012165(Cytochrome-c3 hydrogenase, gamma subunit)|interpro:IPR019480|interpro:IPR017927|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR000951(Phthalate dioxygenase reductase, FPNCR module)|interpro:IPR017938|rcsb pdb:1EP1|rcsb pdb:1EP2|rcsb pdb:1EP3|ensemblbacteria:CAL97699(transcript)|ensemblbacteria:llmg_1105(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0009055"(electron transfer activity)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR023455|refseq:WP_011835013.1|interpro:IPR039261|interpro:IPR037117	-	-	-	assembly:tetrameric, multimeric|3d-r-factors:working 80.500%, free 76.300%|3d-resolution:2.1A|dataset:PDBe - Data obtained from the Protein Data Bank Europe	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2004/02/12	2014/10/16	rogid:LPFgr/BepSPUJS5rdL0TVgpdnO0416870	rogid:V4TuH2Eo05cOdgzNXKxSUSVnO8E416870	intact-crc:A3A13CE7B11C278F|rigid:fpWtXtx8iYntdsiSV8R2WJyBeHo	false	sufficient binding region:1-311	sufficient binding region:1-262	1	1	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)