#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16054 uniprotkb:P70313 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298920|ensembl:ENSMUSP00000030834|uniprotkb:O55056|uniprotkb:Q7TSV7 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:nos3_mouse(display_long)|uniprotkb:Nos3(gene name)|psi-mi:Nos3(display_short)|uniprotkb:Ecnos(gene name synonym)|uniprotkb:Endothelial NOS(gene name synonym)|uniprotkb:EC-NOS(gene name synonym)|uniprotkb:NOS type III(gene name synonym)|uniprotkb:Constitutive NOS(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000028978(gene)|ensembl:ENSMUST00000030834(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0003100"(regulation of systemic arterial blood pressure by endothelin)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0010181"(FMN binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014740"(negative regulation of muscle hyperplasia)|go:"GO:0014806"(smooth muscle hyperplasia)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030324"(lung development)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0031644"(regulation of nervous system process)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046872"(metal ion binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|reactome:R-MMU-1222556|reactome:R-MMU-1474151|reactome:R-MMU-203615|reactome:R-MMU-203641|reactome:R-MMU-203754|reactome:R-MMU-392154|reactome:R-MMU-5218920|reactome:R-MMU-9009391|refseq:NP_032739.3|dip:DIP-31086N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:ZrCc6I1lYQVT+/No+jj0KhLkqPU10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:O35643 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-348937|uniprotkb:Q3TXG4|uniprotkb:Q922E2|ensembl:ENSMUSP00000009234 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:ap1b1_mouse(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N refseq:NP_031480.2|ensembl:ENSMUSG00000009090(gene)|ensembl:ENSMUST00000009234(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048268"(clathrin coat assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:zTEB4qq5OQCyxOOnVs9OeWAQBqA10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P14901 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299000|ensembl:ENSMUSP00000005548 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:hmox1_mouse(display_long)|uniprotkb:Hmox1(gene name)|psi-mi:Hmox1(display_short)|uniprotkb:P32 protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0002246"(wound healing involved in inflammatory response)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0004630"(phospholipase D activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006788"(heme oxidation)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008219"(cell death)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032764"(negative regulation of mast cell cytokine production)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042167"(heme catabolic process)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0043627"(response to estrogen)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|mint:P14901|reactome:R-MMU-189483|reactome:R-MMU-917937|reactome:R-MMU-9609523|reactome:R-MMU-9707564|reactome:R-MMU-9707587|ensembl:ENSMUSG00000005413(gene)|ensembl:ENSMUST00000005548(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|refseq:NP_034572.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:UqAfpYwWVllusAkONxCAZKyU0zQ10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q61221 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298954|ensembl:ENSMUSP00000021530|uniprotkb:O08741|uniprotkb:O08993|uniprotkb:Q61664|uniprotkb:Q61665|uniprotkb:Q8C681|uniprotkb:Q8CC19|uniprotkb:Q8CCB6|uniprotkb:Q8R385|uniprotkb:Q9CYA8 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:hif1a_mouse(display_long)|uniprotkb:Hif1a(gene name)|psi-mi:Hif1a(display_short)|uniprotkb:ARNT-interacting protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000021109(gene)|ensembl:ENSMUST00000021530(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001568"(blood vessel development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060992"(response to fungicide)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q61221|rcsb pdb:4ZPR|reactome:R-MMU-1234158|reactome:R-MMU-1234174|reactome:R-MMU-1234176|reactome:R-MMU-5689880|reactome:R-MMU-8857538|reactome:R-MMU-8951664|refseq:NP_001300848.1|refseq:NP_001300849.1|refseq:NP_034561.2|refseq:XP_017170450.1|dip:DIP-31083N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:1jBCL7bIWP7x+b9k/mCB131AQuA10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P31938 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298860|ensembl:ENSMUSP00000005066 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mp2k1_mouse(display_long)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000004936(gene)|ensembl:ENSMUST00000005066(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-110056|reactome:R-MMU-170968|reactome:R-MMU-445144|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5674499|refseq:NP_032953.1|dip:DIP-467N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:OOj1juW9l4rnEH/W3CjXWZFKMvw10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q05769 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298933|ensembl:ENSMUSP00000035065|uniprotkb:Q543K3 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:pgh2_mouse(display_long)|uniprotkb:Ptgs2(gene name)|psi-mi:Ptgs2(display_short)|uniprotkb:Cox-2(gene name synonym)|uniprotkb:Cox2(gene name synonym)|uniprotkb:Pghs-b(gene name synonym)|uniprotkb:Tis10(gene name synonym)|uniprotkb:Gripghs(gene name synonym)|uniprotkb:TIS10 protein(gene name synonym)|uniprotkb:Macrophage activation-associated marker protein P71/73(gene name synonym)|uniprotkb:PES-2(gene name synonym)|uniprotkb:Cyclooxygenase-2(gene name synonym)|uniprotkb:Prostaglandin-endoperoxide synthase 2(gene name synonym)|uniprotkb:Prostaglandin H2 synthase 2(gene name synonym)|uniprotkb:PHS II(gene name synonym)|uniprotkb:Glucocorticoid-regulated inflammatory cyclooxygenase(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0016702"(oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030282"(bone mineralization)|go:"GO:0030728"(ovulation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031622"(positive regulation of fever generation)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032227"(negative regulation of synaptic transmission, dopaminergic)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033280"(response to vitamin D)|go:"GO:0034097"(response to cytokine)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042633"(hair cycle)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0046697"(decidualization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071284"(cellular response to lead ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071471"(cellular response to non-ionic osmotic stress)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090271"(positive regulation of fibroblast growth factor production)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0090362"(positive regulation of platelet-derived growth factor production)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029576|interpro:IPR037120|rcsb pdb:1CVU|rcsb pdb:1CX2|rcsb pdb:1DCX|rcsb pdb:1DD0|rcsb pdb:1DDX|rcsb pdb:1PXX|rcsb pdb:3HS5|rcsb pdb:3HS6|rcsb pdb:3HS7|rcsb pdb:3KRK|rcsb pdb:3LN0|rcsb pdb:3LN1|rcsb pdb:3MDL|rcsb pdb:3MQE|rcsb pdb:3NT1|rcsb pdb:3NTB|rcsb pdb:3NTG|rcsb pdb:3OLT|rcsb pdb:3OLU|rcsb pdb:3PGH|rcsb pdb:3Q7D|rcsb pdb:3QH0|rcsb pdb:3QMO|rcsb pdb:3RR3|rcsb pdb:3TZI|rcsb pdb:4COX|rcsb pdb:4E1G|rcsb pdb:4FM5|rcsb pdb:4M10|rcsb pdb:4M11|rcsb pdb:4OTJ|rcsb pdb:4OTY|rcsb pdb:4PH9|rcsb pdb:4RRW|rcsb pdb:4RRX|rcsb pdb:4RRY|rcsb pdb:4RRZ|rcsb pdb:4RS0|rcsb pdb:4RUT|rcsb pdb:4Z0L|rcsb pdb:5COX|rcsb pdb:5FDQ|rcsb pdb:5JVY|rcsb pdb:5JVZ|rcsb pdb:5JW1|rcsb pdb:5W58|rcsb pdb:6BL3|rcsb pdb:6BL4|rcsb pdb:6COX|rcsb pdb:6OFY|rcsb pdb:6V3R|reactome:R-MMU-197264|reactome:R-MMU-2142770|reactome:R-MMU-2162123|reactome:R-MMU-9018677|reactome:R-MMU-9018679|reactome:R-MMU-9025094|reactome:R-MMU-9027604|ensembl:ENSMUSG00000032487(gene)|ensembl:ENSMUST00000035065(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001525"(angiogenesis)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004666"(prostaglandin-endoperoxide synthase activity)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005901"(caveola)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007566"(embryo implantation)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009750"(response to fructose)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010942"(positive regulation of cell death)|refseq:NP_035328.2|dip:DIP-31082N - - "mimix:comment":not sure if the protein origin is right determined, my suggestion is based on fig.1c and 1d description comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:qEZAEY7+mfcvc5oe6aZ25me/MsY10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q9R0B8 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298911 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:q9r0b8_mouse(display_long) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR020849|interpro:IPR027417 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:eWBiq7KaWotR/A/oUnMnjGDtjTU10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P29477 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298897|ensembl:ENSMUSP00000018610|uniprotkb:O70515|uniprotkb:O70516|uniprotkb:Q5SXT3|uniprotkb:Q6P6A0|uniprotkb:Q8R410 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:nos2_mouse(display_long)|uniprotkb:Nos2(gene name)|psi-mi:Nos2(display_short)|uniprotkb:Inosl(gene name synonym)|uniprotkb:Inducible NO synthase(gene name synonym)|uniprotkb:NOS type II(gene name synonym)|uniprotkb:Macrophage NOS(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase NOS2(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N interpro:IPR023173|interpro:IPR029039|interpro:IPR036119|interpro:IPR039261|rcsb pdb:1DD7|rcsb pdb:1DF1|rcsb pdb:1DWV|rcsb pdb:1DWW|rcsb pdb:1DWX|rcsb pdb:1JWJ|rcsb pdb:1JWK|rcsb pdb:1M8D|interpro:IPR017938|rcsb pdb:1M8E|rcsb pdb:1M8H|rcsb pdb:1M8I|rcsb pdb:1M9T|rcsb pdb:1N2N|rcsb pdb:1NOC|rcsb pdb:1NOD|rcsb pdb:1NOS|rcsb pdb:1QOM|rcsb pdb:2NOS|rcsb pdb:2ORO|rcsb pdb:2ORP|rcsb pdb:2ORQ|rcsb pdb:2ORR|rcsb pdb:2ORS|rcsb pdb:2ORT|rcsb pdb:2Y37|rcsb pdb:3DWJ|rcsb pdb:3E65|rcsb pdb:3E67|rcsb pdb:3E68|rcsb pdb:3E6L|rcsb pdb:3E6N|rcsb pdb:3E6O|rcsb pdb:3E6T|rcsb pdb:3E7I|rcsb pdb:3E7M|rcsb pdb:3E7T|rcsb pdb:3EAI|rcsb pdb:3EBD|rcsb pdb:3EBF|rcsb pdb:1QW4|rcsb pdb:1QW5|rcsb pdb:3GOF|rcsb pdb:3NOD|rcsb pdb:3NQS|rcsb pdb:3NW2|rcsb pdb:4JS9|rcsb pdb:4UX6|reactome:R-MMU-1222556|rcsb pdb:1R35|reactome:R-MMU-392154|rcsb pdb:1VAF|reactome:R-MMU-9033241|rcsb pdb:2BHJ|rcsb pdb:2NOD|ensembl:ENSMUSG00000020826(gene)|ensembl:ENSMUST00000018610(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016709"("oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen")|go:"GO:0003779"(actin binding)|go:"GO:0004517"(nitric-oxide synthase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0020037"(heme binding)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031284"(positive regulation of guanylate cyclase activity)|go:"GO:0032310"(prostaglandin secretion)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0006954"(inflammatory response)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0034618"(arginine binding)|go:"GO:0035690"|go:"GO:0009617"(response to bacterium)|go:"GO:0009725"(response to hormone)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0010181"(FMN binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051712"(positive regulation of killing of cells of another organism)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|interpro:IPR001094(Flavodoxin-like)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR003097(FAD-binding, type 1)|interpro:IPR004030(Nitric oxide synthase, oxygenase region)|interpro:IPR008254(Flavodoxin/nitric oxide synthase)|interpro:IPR012144(Nitric-oxide synthase)|interpro:IPR017927|refseq:NP_035057.1|refseq:NP_001300850.1|refseq:NP_001300851.1|dip:DIP-31080N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:ZJ5M1BnSL0l2eW+3eGeZ6bVqUiA10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:O35558 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298883 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:o35558_mouse(display_long)|uniprotkb:Erk2(gene name)|psi-mi:Erk2(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005901"(caveola)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site) - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:sEAzCVBYa6tBU8cmQY8SVXVbYF010090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q63844 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-397682|uniprotkb:Q61531|uniprotkb:Q8K0X5|uniprotkb:Q91YW5|ensembl:ENSMUSP00000051619 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mk03_mouse(display_long)|uniprotkb:Mapk3(gene name)|psi-mi:Mapk3(display_short)|uniprotkb:Extracellular signal-regulated kinase 1(gene name synonym)|uniprotkb:Insulin-stimulated MAP2 kinase(gene name synonym)|uniprotkb:p44-ERK1(gene name synonym)|uniprotkb:ERT2(gene name synonym)|uniprotkb:MAP kinase isoform p44(gene name synonym)|uniprotkb:Microtubule-associated protein 2 kinase(gene name synonym)|uniprotkb:MNK1(gene name synonym)|uniprotkb:Erk1(gene name synonym)|uniprotkb:Prkm3(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N refseq:NP_036082.1|dip:DIP-31078N|go:"GO:0007568"(aging)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSMUSG00000063065(gene)|ensembl:ENSMUST00000057669(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|reactome:R-MMU-9627069|reactome:R-MMU-982772|go:"GO:0060440"(trachea formation)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904417"(positive regulation of xenophagy)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000657"(negative regulation of apolipoprotein binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q63844|reactome:R-MMU-110056|reactome:R-MMU-112409|reactome:R-MMU-1169408|reactome:R-MMU-1295596|reactome:R-MMU-162658|reactome:R-MMU-170968|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2029482|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-2871796|reactome:R-MMU-3371453|reactome:R-MMU-375165|reactome:R-MMU-445144|reactome:R-MMU-450341|reactome:R-MMU-456926|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-5663213|reactome:R-MMU-5668599|reactome:R-MMU-5673001|reactome:R-MMU-5674135|reactome:R-MMU-5674499|reactome:R-MMU-5675221|reactome:R-MMU-6811558|reactome:R-MMU-73728|reactome:R-MMU-74749|reactome:R-MMU-881907|reactome:R-MMU-8939211 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:I2hStA4IjS6t6Ky7fb9zFPOcZag10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q61194 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298605|uniprotkb:Q61182 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:p3c2a_mouse(display_long)|uniprotkb:Pik3c2a(gene name)|psi-mi:Pik3c2a(display_short)|uniprotkb:Phosphoinositide 3-kinase-C2-alpha(gene name synonym)|uniprotkb:Cpk-m(gene name synonym)|uniprotkb:p170(gene name synonym)|uniprotkb:Cpk(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N interpro:IPR011009(Protein kinase-like)|refseq:NP_035213.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001683(Phox-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR018936|interpro:IPR002420(Phosphoinositide 3-kinase, C2)|interpro:IPR000341(Phosphoinositide 3-kinase, ras-binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016477"(cell migration)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035005"(1-phosphatidylinositol-4-phosphate 3-kinase activity)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036092"(phosphatidylinositol-3-phosphate biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046934"(phosphatidylinositol-4,5-bisphosphate 3-kinase activity)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0052812"(phosphatidylinositol-3,4-bisphosphate 5-kinase activity)|go:"GO:0071583"(negative regulation of zinc ion transmembrane transport)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1905037"(autophagosome organization)|go:"GO:0030276"(clathrin binding)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|rcsb pdb:2B3R|interpro:IPR042133|interpro:IPR042236|interpro:IPR037705|interpro:IPR029071|reactome:R-MMU-1660517|interpro:IPR035892|interpro:IPR036871|interpro:IPR036940|reactome:R-MMU-1660499|reactome:R-MMU-1660514|reactome:R-MMU-1660516|reactome:R-MMU-432722|reactome:R-MMU-8856828 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:AqEyCpzwe6rZHVJBxdUdWahf57A10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q9WTU6 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298798|ensembl:ENSMUSP00000042744|ensembl:ENSMUSP00000136977|uniprotkb:Q8C097|uniprotkb:Q8VDD2|uniprotkb:Q9WTU4|uniprotkb:Q9WTU5|uniprotkb:Q5NCK9|uniprotkb:Q5NCL5 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mk09_mouse(display_long)|uniprotkb:Mapk9(gene name)|psi-mi:Mapk9(display_short)|uniprotkb:Jnk2(gene name synonym)|uniprotkb:Prkm9(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK2(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 2(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000020366(gene)|ensembl:ENSMUST00000043321(transcript)|ensembl:ENSMUST00000178543(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0004672"(protein kinase activity)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010770"(positive regulation of cell morphogenesis involved in differentiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031175"(neuron projection development)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0042493"|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-450321|reactome:R-MMU-450341|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0032722"(positive regulation of chemokine production)|refseq:NP_001157143.1|refseq:NP_001157144.1|refseq:NP_058657.1|refseq:NP_997575.2|ensembl:ENSMUSG00000020366|dip:DIP-31076N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:m/9TybdDExPF8ah6GnnWDbHSgyA10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q91Y86 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298784|ensembl:ENSMUSP00000107576 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mk08_mouse(display_long)|uniprotkb:Mapk8(gene name)|psi-mi:Mapk8(display_short)|uniprotkb:Jnk1(gene name synonym)|uniprotkb:Prkm8(gene name synonym)|uniprotkb:Stress-activated protein kinase JNK1(gene name synonym)|uniprotkb:c-Jun N-terminal kinase 1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0009411"(response to UV)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019894"(kinesin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048263"(determination of dorsal identity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097441"(basal dendrite)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901485"(positive regulation of transcription factor catabolic process)|go:"GO:1902595"(regulation of DNA replication origin binding)|go:"GO:1904809"(regulation of dense core granule transport)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|mint:Q91Y86|reactome:R-MMU-139910|reactome:R-MMU-193648|reactome:R-MMU-2559580|reactome:R-MMU-2871796|reactome:R-MMU-376172|reactome:R-MMU-450321|reactome:R-MMU-450341|reactome:R-MMU-5693565|reactome:R-MMU-9007892|reactome:R-MMU-111446|ensembl:ENSMUSG00000021936(gene)|ensembl:ENSMUST00000111945(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001764"(neuron migration)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004705"(JUN kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007254"(JNK cascade)|go:"GO:0007258"(JUN phosphorylation)|go:"GO:0009408"(response to heat)|refseq:NP_057909.1|dip:DIP-31075N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:PF6G6rHf26jidt+Mg3aFCvCm7pU10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P49138 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298776|ensembl:ENSMUSP00000016672|uniprotkb:Q6P561 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mapk2_mouse(display_long)|uniprotkb:Mapkapk2(gene name)|psi-mi:Mapkapk2(display_short)|uniprotkb:Rps6kc1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000016528(gene)|ensembl:ENSMUST00000016672(transcript)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034097"(response to cytokine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0044351"(macropinocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048839"(inner ear development)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027442|mint:P49138|reactome:R-MMU-171007|reactome:R-MMU-199920|reactome:R-MMU-2142691|reactome:R-MMU-2559580|reactome:R-MMU-3371453|reactome:R-MMU-4420097|reactome:R-MMU-450302|reactome:R-MMU-450385|reactome:R-MMU-450513|refseq:NP_032577.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:xk1272ba9Ly1mUVJnB8Ya/3fyyY10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P47811 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298727|ensembl:ENSMUSP00000061958|uniprotkb:O08666|uniprotkb:Q3U6R5|uniprotkb:Q3UZS3|uniprotkb:Q8C289|uniprotkb:Q9JLV8|uniprotkb:Q9QZ80|uniprotkb:B2KF37|uniprotkb:B2KF38 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mk14_mouse(display_long)|uniprotkb:Mapk14(gene name)|psi-mi:Mapk14(display_short)|uniprotkb:Crk1(gene name synonym)|uniprotkb:Csbp1(gene name synonym)|uniprotkb:Csbp2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase p38 alpha(gene name synonym)|uniprotkb:CRK1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N reactome:R-MMU-4420097|reactome:R-MMU-450302|reactome:R-MMU-450341|reactome:R-MMU-525793|reactome:R-MMU-5668599|reactome:R-MMU-6798695|reactome:R-MMU-6804756|ensembl:ENSMUSG00000053436(gene)|ensembl:ENSMUST00000062694(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000922"(spindle pole)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001890"(placenta development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016301"(kinase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031281"(positive regulation of cyclase activity)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038066"(p38MAPK cascade)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051525"(NFAT protein binding)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|rcsb pdb:1LEZ|rcsb pdb:1YW2|rcsb pdb:1YWR|rcsb pdb:2EWA|rcsb pdb:2GHL|rcsb pdb:2GHM|rcsb pdb:2GTM|rcsb pdb:2GTN|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099179"(regulation of synaptic membrane adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900015"(regulation of cytokine production involved in inflammatory response)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008352(MAP kinase, p38)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR038784|mint:P47811|rcsb pdb:1LEW|rcsb pdb:5R9F|rcsb pdb:5R9G|rcsb pdb:5R9H|rcsb pdb:5R9I|rcsb pdb:2OZA|rcsb pdb:2PUU|rcsb pdb:3P4K|rcsb pdb:3P5K|rcsb pdb:3P78|rcsb pdb:3P79|rcsb pdb:3P7A|rcsb pdb:3P7B|rcsb pdb:3P7C|rcsb pdb:3PY3|rcsb pdb:3TG1|rcsb pdb:4KA3|rcsb pdb:4LOO|rcsb pdb:4LOP|rcsb pdb:4LOQ|rcsb pdb:4TYH|rcsb pdb:5LAR|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5R8U|rcsb pdb:5R8V|rcsb pdb:5R8W|rcsb pdb:5R8X|rcsb pdb:5R8Y|rcsb pdb:5R8Z|rcsb pdb:5R90|rcsb pdb:5R91|rcsb pdb:5R92|rcsb pdb:5R93|rcsb pdb:5R94|rcsb pdb:5R95|rcsb pdb:5R96|rcsb pdb:5R97|rcsb pdb:5R98|rcsb pdb:5R99|rcsb pdb:5R9A|rcsb pdb:5R9B|rcsb pdb:5R9C|rcsb pdb:5R9D|rcsb pdb:5R9E|rcsb pdb:5R9J|rcsb pdb:5R9K|rcsb pdb:5R9L|rcsb pdb:5R9M|rcsb pdb:5R9N|rcsb pdb:5R9O|rcsb pdb:5R9P|rcsb pdb:5R9Q|rcsb pdb:5R9R|rcsb pdb:5R9S|rcsb pdb:5R9T|rcsb pdb:5R9U|rcsb pdb:5R9V|rcsb pdb:5R9W|rcsb pdb:5R9X|rcsb pdb:5R9Y|rcsb pdb:5R9Z|rcsb pdb:5RA0|rcsb pdb:5RA1|rcsb pdb:5RA2|rcsb pdb:5RA3|rcsb pdb:5RA4|rcsb pdb:5RA5|rcsb pdb:5RA6|rcsb pdb:5RA7|rcsb pdb:5RA8|rcsb pdb:5RA9|rcsb pdb:5UOJ|rcsb pdb:6SO1|rcsb pdb:6SO2|rcsb pdb:6SO4|rcsb pdb:6SOD|rcsb pdb:6SOI|rcsb pdb:6SOT|rcsb pdb:6SOU|rcsb pdb:6SOV|rcsb pdb:6SP9|rcsb pdb:6SPL|rcsb pdb:6Y4T|rcsb pdb:6Y4U|rcsb pdb:6Y4V|rcsb pdb:6Y4W|rcsb pdb:6Y4X|rcsb pdb:6Y6V|rcsb pdb:6Y7W|rcsb pdb:6Y7X|rcsb pdb:6Y7Y|rcsb pdb:6Y7Z|rcsb pdb:6Y80|rcsb pdb:6Y81|rcsb pdb:6Y82|rcsb pdb:6Y85|rcsb pdb:6Y8H|rcsb pdb:6YCU|rcsb pdb:6YCW|rcsb pdb:6YJC|rcsb pdb:6YK7|rcsb pdb:6ZWR|rcsb pdb:7BDO|rcsb pdb:7BDQ|rcsb pdb:7BE4|rcsb pdb:7BE5|reactome:R-MMU-168638|reactome:R-MMU-171007|reactome:R-MMU-198753|reactome:R-MMU-2559580|reactome:R-MMU-376172|reactome:R-MMU-418592|reactome:R-MMU-432142|refseq:NP_001161980.1|refseq:NP_001161985.1|refseq:NP_001161986.1|refseq:NP_036081.1|dip:DIP-31073N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:ks/9pIKb9SsZnYW71qj+5v5GVaw10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P31750 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298707|ensembl:ENSMUSP00000001780|uniprotkb:Q62274|uniprotkb:Q6GSA6 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:akt1_mouse(display_long)|uniprotkb:Akt1(gene name)|psi-mi:Akt1(display_short)|uniprotkb:Akt(gene name synonym)|uniprotkb:Rac(gene name synonym)|uniprotkb:RAC-PK-alpha(gene name synonym)|uniprotkb:AKT1 kinase(gene name synonym)|uniprotkb:Proto-oncogene c-Akt(gene name synonym)|uniprotkb:Protein kinase B(gene name synonym)|uniprotkb:Thymoma viral proto-oncogene(gene name synonym)|uniprotkb:Protein kinase B alpha(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0099104"(potassium channel activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903721"(positive regulation of I-kappaB phosphorylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990418"(response to insulin-like growth factor stimulus)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000402"(negative regulation of lymphocyte migration)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR034676|interpro:IPR039026|interpro:IPR039027|mint:P31750|reactome:R-MMU-1257604|reactome:R-MMU-1358803|reactome:R-MMU-1474151|reactome:R-MMU-165159|reactome:R-MMU-198323|reactome:R-MMU-198693|reactome:R-MMU-199418|reactome:R-MMU-203615|reactome:R-MMU-211163|reactome:R-MMU-354192|reactome:R-MMU-3769402|reactome:R-MMU-389357|reactome:R-MMU-389513|reactome:R-MMU-392451|reactome:R-MMU-450385|reactome:R-MMU-450604|reactome:R-MMU-5218920|reactome:R-MMU-5628897|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6811558|reactome:R-MMU-69202|reactome:R-MMU-69656|reactome:R-MMU-8849469|reactome:R-MMU-8876198|reactome:R-MMU-8948751|reactome:R-MMU-9009391|reactome:R-MMU-9604323|reactome:R-MMU-9607240|reactome:R-MMU-9614399|reactome:R-MMU-9634638|ensembl:ENSMUSG00000001729(gene)|ensembl:ENSMUST00000001780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002931"(response to ischemia)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006412"(translation)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006954"(inflammatory response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007281"(germ cell development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008643"(carbohydrate transport)|go:"GO:0009725"(response to hormone)|go:"GO:0010033"(response to organic substance)|go:"GO:0010467"(gene expression)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030030"(cell projection organization)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030212"(hyaluronan metabolic process)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031982"(vesicle)|go:"GO:0031999"(negative regulation of fatty acid beta-oxidation)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032094"(response to food)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035655"(interleukin-18-mediated signaling pathway)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036294"(cellular response to decreased oxygen levels)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046622"(positive regulation of organ growth)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060709"(glycogen cell differentiation involved in embryonic placenta development)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0070141"(response to UV-A)|go:"GO:0070848"(response to growth factor)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|refseq:NP_001159366.1|refseq:NP_033782.1|refseq:XP_006515478.1|refseq:NP_001318036.1|dip:DIP-736N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:qZx+MZ1X4i0lL1kvsVCsxJONKQ410090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P97504 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298692|ensembl:ENSMUSP00000107882 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:bmx_mouse(display_long)|uniprotkb:Bmx(gene name)|psi-mi:Bmx(display_short)|uniprotkb:Bone marrow tyrosine kinase gene in chromosome X protein homolog(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000031377(gene)|ensembl:ENSMUST00000112263(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050853"(B cell receptor signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001562(Tec/Btk)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028840|interpro:IPR036860|reactome:R-MMU-111465|reactome:R-MMU-1660499|refseq:NP_033889.2 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:Mz4s4Lg5067waYLnXlhRRFdvuSg10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P06240 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-1401|ensembl:ENSMUSP00000066209|ensembl:ENSMUSP00000099656|uniprotkb:Q62320|uniprotkb:Q61795|uniprotkb:Q61794|uniprotkb:Q91X65 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:lck_mouse(display_long)|uniprotkb:Lck(gene name)|psi-mi:Lck(display_short)|uniprotkb:Lsk-t(gene name synonym)|uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)|uniprotkb:p56-LCK(gene name synonym)|uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000000409(gene)|ensembl:ENSMUST00000067240(transcript)|ensembl:ENSMUST00000102596(transcript)|go:"GO:0000242"(pericentriolar material)|refseq:NP_001155905.1|refseq:NP_034823.1|refseq:XP_006502881.1|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003823"(antigen binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010038"(response to metal ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045588"(positive regulation of gamma-delta T cell differentiation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051117"(ATPase binding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070474"(positive regulation of uterine smooth muscle contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1903039"(positive regulation of leukocyte cell-cell adhesion)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035749|interpro:IPR035850|interpro:IPR036028|interpro:IPR036860|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-202424|reactome:R-MMU-202427|reactome:R-MMU-202430|reactome:R-MMU-202433|reactome:R-MMU-210990|reactome:R-MMU-2424491|reactome:R-MMU-389356|reactome:R-MMU-389357|reactome:R-MMU-389359|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-6811558|reactome:R-MMU-9013407|reactome:R-MMU-9020558|reactome:R-MMU-9706374 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:yjMU0fxTseBSR5/aEXmp2cR7Mts10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P05480 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298680|ensembl:ENSMUSP00000029175|ensembl:ENSMUSP00000105157|ensembl:ENSMUSP00000105159|uniprotkb:Q2M4I4|intact:EBI-7361449|intact:MINT-142018|uniprotkb:F8WI90 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:src_mouse(display_long)|uniprotkb:Src(gene name)|psi-mi:Src(display_short)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902533"(positive regulation of intracellular signal transduction)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P05480|rcsb pdb:6F3F|reactome:R-MMU-1227986|reactome:R-MMU-1251985|reactome:R-MMU-1253288|reactome:R-MMU-1257604|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-1433559|reactome:R-MMU-177929|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-191650|reactome:R-MMU-2029481|reactome:R-MMU-210990|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-389356|reactome:R-MMU-389513|reactome:R-MMU-3928662|reactome:R-MMU-3928663|reactome:R-MMU-3928664|reactome:R-MMU-3928665|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418885|reactome:R-MMU-430116|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-456926|reactome:R-MMU-5218921|reactome:R-MMU-5607764|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-6811558|reactome:R-MMU-69231|reactome:R-MMU-8853659|reactome:R-MMU-8874081|reactome:R-MMU-8934903|reactome:R-MMU-8941858|reactome:R-MMU-9009391|reactome:R-MMU-9603381|ensembl:ENSMUSG00000027646(gene)|ensembl:ENSMUST00000029175(transcript)|ensembl:ENSMUST00000109531(transcript)|ensembl:ENSMUST00000109533(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|refseq:NP_001020566.1|refseq:NP_033297.2|dip:DIP-31071N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:SY8bQUpE/ni7hRMp4F02ygRsU7Q10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P23242 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298630|ensembl:ENSMUSP00000064536|ensembl:ENSMUSP00000151620|uniprotkb:Q544I7|uniprotkb:Q8CE05 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:cxa1_mouse(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0005771"(multivesicular body)|go:"GO:0030054"(cell junction)|ensembl:ENSMUSG00000050953(gene)|ensembl:ENSMUST00000068581(transcript)|ensembl:ENSMUST00000220069(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0003347"(epicardial cell to mesenchymal cell transition)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0009268"(response to pH)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0005882"(intermediate filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0005886"(plasma membrane)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007154"(cell communication)|go:"GO:0016020"(membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0086075"(gap junction channel activity involved in cardiac conduction electrical coupling)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0070160"(tight junction)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P23242|reactome:R-MMU-190840|reactome:R-MMU-190861|reactome:R-MMU-190873|reactome:R-MMU-191650|reactome:R-MMU-196025|reactome:R-MMU-9013406|go:"GO:1905867"(epididymis development)|refseq:NP_034418.1|dip:DIP-29207N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:y7Yg1+W6tlVZnaRALQBCWQppVf010090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P70304 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298619 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:p70304_mouse(display_long)|uniprotkb:Pik3r1(gene name)|psi-mi:Pik3r1(display_short)|uniprotkb:Phosphatidylinositol 3-kinase regulatory subunit alpha(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N interpro:IPR000198(RhoGAP)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR032498|interpro:IPR035020|interpro:IPR035022|interpro:IPR035591|interpro:IPR036028|interpro:IPR036860|interpro:IPR044124|go:"GO:0016301"(kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0015031"(protein transport)|dip:DIP-118N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:f9V3VP6wUj0wGGg4YV7DFMFx9zk10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P51667 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298593|uniprotkb:Q6P8P4|uniprotkb:Q9QVP3|ensembl:ENSMUSP00000014080|ensembl:ENSMUSP00000107380 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:mlrv_mouse(display_long)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Myl2(gene name)|psi-mi:Myl2(display_short)|uniprotkb:Mylpc(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0043292"(contractile fiber)|go:"GO:0055001"(muscle cell development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P51667|reactome:R-MMU-390522|go:"GO:0042694"(muscle cell fate specification)|ensembl:ENSMUSG00000013936(gene)|ensembl:ENSMUST00000014080(transcript)|ensembl:ENSMUST00000111751(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|refseq:NP_034991.3 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:Skjc00qypNcSdNKEoHRPei83rUY10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P51637 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298576|ensembl:ENSMUSP00000074922 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P31001 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298565|ensembl:ENSMUSP00000027409 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:desm_mouse(display_long)|uniprotkb:Des(gene name)|psi-mi:Des(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N refseq:NP_034173.1|go:"GO:0005916"(fascia adherens)|ensembl:ENSMUSG00000026208(gene)|ensembl:ENSMUST00000027409(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|mint:P31001|reactome:R-MMU-390522|go:"GO:0005921"(gap junction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014704"(intercalated disc)|go:"GO:0030018"(Z disc)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043292"(contractile fiber)|go:"GO:0045098"(type III intermediate filament)|dip:DIP-256N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:00+9If1SeTNgGlloChCKgqWMtFo10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q61033 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298533|uniprotkb:Q61028|uniprotkb:B2RUB9|ensembl:ENSMUSP00000020123 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:lap2a_mouse(display_long)|uniprotkb:Tmpo(gene name)|psi-mi:Tmpo(display_short)|uniprotkb:Lap2(gene name synonym)|uniprotkb:Thymopoietin isoforms alpha/zeta(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N refseq:NP_035735.2|ensembl:ENSMUSG00000019961(gene)|ensembl:ENSMUST00000020123(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:Q61033|rcsb pdb:2V0X|dip:DIP-29323N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:o6vl4AiTLnLFMEqN52CXczOZ90810090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q62486 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298530 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:q62486_mouse(display_long)|uniprotkb:unknown(gene name)|psi-mi:unknown(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N - - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:6UoLb7YHpVz4/O1r8HOgZZawSWM10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q921M4 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298519|ensembl:ENSMUSP00000109004|uniprotkb:A2AN43|uniprotkb:A2AN47 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:goga2_mouse(display_long)|uniprotkb:Golga2(gene name)|psi-mi:Golga2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N go:"GO:0019905"(syntaxin binding)|refseq:NP_001074437.1|ensembl:ENSMUSG00000002546(gene)|ensembl:ENSMUST00000113377(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051645"(Golgi localization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q921M4|reactome:R-MMU-162658|reactome:R-MMU-204005|reactome:R-MMU-6807878|reactome:R-MMU-9013148|reactome:R-MMU-9013405|refseq:XP_006498556.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:GMrTr2bHQ0lyJ7MV2kNF5+7fhAk10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P67778 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298507|uniprotkb:P24142|uniprotkb:Q3UB75|uniprotkb:Q5SQG4|ensembl:ENSMUSP00000119603 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:phb_mouse(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)|uniprotkb:B-cell receptor-associated protein 32(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000038845(gene)|ensembl:ENSMUST00000125172(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P67778|reactome:R-MMU-5673000|reactome:R-MMU-8949664|refseq:NP_032857.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P58771 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298478|uniprotkb:P02558|uniprotkb:P19354|uniprotkb:P46902|uniprotkb:P99034|ensembl:ENSMUSP00000109315 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:tpm1_mouse(display_long)|uniprotkb:Tpm-1(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000032366(gene)|ensembl:ENSMUST00000113685(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:P58771|rcsb pdb:7NEP|reactome:R-MMU-390522|reactome:R-MMU-445355|go:"GO:0003779"(actin binding)|refseq:NP_001157720.1|refseq:NP_077745.2|dip:DIP-300N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q6P3Z7 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298475|ensembl:ENSMUSP00000137093|ensembl:ENSMUSP00000140941 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:q6p3z7_mouse(display_long)|uniprotkb:Tnnt2(gene name)|psi-mi:Tnnt2(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUST00000179863(transcript)|ensembl:ENSMUST00000188028(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030172"(troponin C binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031013"(troponin I binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|ensembl:ENSMUSG00000026414(gene)|refseq:NP_001123646.1|refseq:NP_001123648.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:JyrpkMPTR/NkiK++GDE8cMn+eTo10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q61275 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-298466 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:q61275_mouse(display_long)|uniprotkb:Actc1(gene name)|psi-mi:Actc1(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N interpro:IPR004001(Actin, conserved site)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:ETF+Ntm8pD7ExXvZCgyLGB1Pv0010090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q9QVP9 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299061|ensembl:ENSMUSP00000022622|ensembl:ENSMUSP00000137008|uniprotkb:B2RQ16|uniprotkb:G3X8V1 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:fak2_mouse(display_long)|uniprotkb:Pyk2(gene name synonym)|uniprotkb:Raftk(gene name synonym)|uniprotkb:Ptk2b(gene name)|psi-mi:Ptk2b(display_short)|uniprotkb:Fak2(gene name synonym)|uniprotkb:Focal adhesion kinase 2(gene name synonym)|uniprotkb:Proline-rich tyrosine kinase 2(gene name synonym)|uniprotkb:Cell adhesion kinase beta(gene name synonym)|uniprotkb:Calcium-dependent tyrosine kinase(gene name synonym)|uniprotkb:Related adhesion focal tyrosine kinase(gene name synonym)|uniprotkb:Calcium-regulated non-receptor proline-rich tyrosine kinase(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000059456(gene)|ensembl:ENSMUST00000022622(transcript)|ensembl:ENSMUST00000178730(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001525"(angiogenesis)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006968"(cellular defense response)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009725"(response to hormone)|go:"GO:0009749"(response to glucose)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0010752"(regulation of cGMP-mediated signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032960"(regulation of inositol trisphosphate biosynthetic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043197"(dendritic spine)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0043423"(3-phosphoinositide-dependent protein kinase binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051591"(response to cAMP)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000538"(positive regulation of B cell chemotaxis)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR005189(Focal adhesion targeting region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019748|interpro:IPR019749|interpro:IPR020635|interpro:IPR029071|interpro:IPR030610|interpro:IPR035963|interpro:IPR036137|interpro:IPR041390|interpro:IPR041784|mint:Q9QVP9|reactome:R-MMU-391160|reactome:R-MMU-4420097|reactome:R-MMU-9020558|refseq:XP_006518789.1|refseq:XP_011243296.1|refseq:NP_001155838.1 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:wFolkPm20C8WJ9CP/rnhc2FxqT410090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P23927 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P14602 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299023|ensembl:ENSMUSP00000005077 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:Q61696 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299016|ensembl:ENSMUSP00000084586|uniprotkb:Q61697|uniprotkb:Q7TQD8|uniprotkb:Q9QWJ5 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:hs71a_mouse(display_long)|uniprotkb:Hspa1a(gene name)|psi-mi:Hspa1a(display_short)|uniprotkb:Heat shock 70 kDa protein 3(gene name synonym)|uniprotkb:Hsp68(gene name synonym)|uniprotkb:Hsp70-3(gene name synonym)|uniprotkb:Hsp70A1(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000091971(gene)|ensembl:ENSMUST00000087328(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045121"(membrane raft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:Q61696|reactome:R-MMU-3371453|reactome:R-MMU-450408|reactome:R-MMU-6798695|refseq:NP_034609.2 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:8ekBPoJrpT+Hr1LvZpflCkZEsss10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P16054 uniprotkb:P45376 intact:EBI-298451|ensembl:ENSMUSP00000094873|ensembl:ENSMUSP00000094874 intact:EBI-299007|ensembl:ENSMUSP00000100045|uniprotkb:O70130|uniprotkb:Q99KC9 psi-mi:kpce_mouse(display_long)|uniprotkb:Prkce(gene name)|psi-mi:Prkce(display_short)|uniprotkb:Pkce(gene name synonym)|uniprotkb:Pkcea(gene name synonym)|uniprotkb:nPKC-epsilon(gene name synonym) psi-mi:aldr_mouse(display_long)|uniprotkb:Akr1b1(gene name)|psi-mi:Akr1b1(display_short)|uniprotkb:Aldor1(gene name synonym)|uniprotkb:Aldr1(gene name synonym)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:Akr1b3(gene name synonym)|uniprotkb:Aldo-keto reductase family 1 member B3(gene name synonym)|uniprotkb:Aldose reductase(gene name synonym)|uniprotkb:Alr2(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Ping et al. (2001) pubmed:11139474 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-298523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000045038(gene)|ensembl:ENSMUST00000097274(transcript)|ensembl:ENSMUST00000097275(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004699"(calcium-independent protein kinase C activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014376(Protein kinase C, delta/epsilon/eta/theta types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR027274|interpro:IPR034669|interpro:IPR035892|reactome:R-MMU-114508|reactome:R-MMU-1250196|reactome:R-MMU-1489509|reactome:R-MMU-2029485|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0005829"(cytosol)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035276"(ethanol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071944"(cell periphery)|go:"GO:0043278"(response to morphine)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0106311"|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2001031"(positive regulation of cellular glucuronidation)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050996"(positive regulation of lipid catabolic process)|interpro:IPR000719(Protein kinase, core)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051280"(negative regulation of release of sequestered calcium ion into cytosol)|interpro:IPR000961(Protein kinase, C-terminal)|go:"GO:0051301"(cell division)|refseq:NP_035234.1|dip:DIP-31066N ensembl:ENSMUSG00000001642(gene)|ensembl:ENSMUST00000102980(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005996"(monosaccharide metabolic process)|go:"GO:0006061"(sorbitol biosynthetic process)|go:"GO:0009414"(response to water deprivation)|go:"GO:0010033"(response to organic substance)|go:"GO:0018505"(cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032838"(plasma membrane bounded cell projection cytoplasm)|go:"GO:0033010"(paranodal junction)|go:"GO:0035809"(regulation of urine volume)|go:"GO:0036130"(prostaglandin H2 endoperoxidase reductase activity)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0042629"(mast cell granule)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043795"(glyceraldehyde oxidoreductase activity)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0052650"(NADP-retinol dehydrogenase activity)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0072061"(inner medullary collecting duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:0097238"(cellular response to methylglyoxal)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:1901360"(organic cyclic compound metabolic process)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|mint:P45376|reactome:R-MMU-196108|reactome:R-MMU-5652227|refseq:NP_033788.3 - - - comment:Refer to paper for the functional distribution of the proteins and their PTM.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse. taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue]) - 2004/03/10 2021/02/11 rogid:LBpr5ejW6fnkKwlXL6akJYv3H1M10090 rogid:h2dDmCsHxVwUhOeEhpxDrqGzXfc10090 intact-crc:14F103861637D925|rigid:Jb7W3gZBfKAaRChoxffPvtjps9A false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting)