#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NY61 uniprotkb:P52435 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Fanciulli et al. (2000) pubmed:10783144|mint:MINT-5212527 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7274145|mint:MINT-49956 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|mint:MINT-417437(identity) refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N|mint:MINT-417443(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" figure legend:F1C|comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/09 2014/10/16 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 intact-crc:82CF4234230F90BE|rigid:CJil9W/VgMDA8HdWYCbVzycVjic false binding-associated region:271-313(MINT-417438) binding-associated region:87-117(MINT-417444)|tag:?-?(MINT-417447) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99708 uniprotkb:Q9NY61 intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0096"(pull down) Fanciulli et al. (2000) pubmed:10783144|mint:MINT-5212527 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7274167|mint:MINT-49957 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-417429(identity) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|mint:MINT-417423(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/09 2014/10/16 rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 intact-crc:F2AD992A3CF2538B|rigid:C4IG0Qrk8DiNdYkIDcWLqnrMtog false tag:?-?(MINT-417430) binding-associated region:314-370(MINT-417424) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NY61 uniprotkb:Q99708 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym) psi-mi:"MI:0096"(pull down) Fanciulli et al. (2000) pubmed:10783144|mint:MINT-5212527 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7274184|mint:MINT-49958 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|mint:MINT-417489(identity) refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-417495(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2004/06/09 2014/10/16 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606 intact-crc:965E8BE388F2DE91|rigid:C4IG0Qrk8DiNdYkIDcWLqnrMtog false binding-associated region:314-370(MINT-417490) tag:?-?(MINT-417496) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9NY61 uniprotkb:P52435 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0018"(two hybrid) Fanciulli et al. (2000) pubmed:10783144|mint:MINT-5212527 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7274227|mint:MINT-49955 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|mint:MINT-417471(identity) refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N|mint:MINT-417479(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/06/09 2014/10/16 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 intact-crc:CA4B828D78A2DAB9|rigid:CJil9W/VgMDA8HdWYCbVzycVjic false binding-associated region:271-313(MINT-417472)|tag:?-?(MINT-417474) mutation decreasing interaction:87-117(MINT-417480)|tag:?-?(MINT-417482) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99708 uniprotkb:Q9NY61 intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3 intact:EBI-372428|uniprotkb:A6NCJ6|uniprotkb:Q9P0A4|uniprotkb:Q9UNX5|uniprotkb:B3KQ26|intact:EBI-28984804|ensembl:ENSP00000477848|ensembl:ENSP00000481894 psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym) psi-mi:aatf_human(display_long)|uniprotkb:Apoptosis-antagonizing transcription factor(gene name synonym)|uniprotkb:Rb-binding protein Che-1(gene name synonym)|uniprotkb:AATF(gene name)|psi-mi:AATF(display_short)|uniprotkb:CHE1(gene name synonym)|uniprotkb:DED(gene name synonym)|uniprotkb:HSPC277(orf name) psi-mi:"MI:0018"(two hybrid) Fanciulli et al. (2000) pubmed:10783144|mint:MINT-5212527 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7274251|mint:MINT-49961 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-417457(identity) refseq:NP_036270.1|ensembl:ENSG00000275700(gene)|ensembl:ENSG00000276072(gene)|ensembl:ENST00000619387(transcript)|ensembl:ENST00000620004(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR012617(TRAUB)|interpro:IPR025160|interpro:IPR039223|mint:Q9NY61|rcsb pdb:5W6A|reactome:R-HSA-193648|ensembl:ENSP00000477848|ensembl:ENSP00000481894|mint:MINT-417463(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:homomint|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2004/06/09 2014/10/16 rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606 rogid:yv0URVqqWKOlJws34IX1T/vBipI9606 intact-crc:11D6FB59A7EFD951|rigid:C4IG0Qrk8DiNdYkIDcWLqnrMtog false tag:?-?(MINT-417458) tag:?-?(MINT-417464) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)