#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P13098 uniprotkb:P08181 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0096"(pull down) Trott et al. (2001) pubmed:11208814|mint:MINT-5213561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7773762|mint:MINT-17272 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-468427(identity) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N|mint:MINT-468424(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:CKII binds and phosphorylaes m8 on Ser159. Changing Ser into Ala binding is decresed. By changing Ser into Asp, binding is abolished.|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/04 2014/10/16 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:828483A1856961E2|rigid:jm4iqqbCe8IB3dyz972letTG8ws false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08181 uniprotkb:P13097 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 intact:EBI-178179|intact:EBI-1639161|uniprotkb:Q9VBI6|uniprotkb:Q5S487|uniprotkb:Q5S4J5|ensemblmetazoa:FBpp0084334 psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:esm7_drome(display_long)|uniprotkb:"E(spl)m7-HLH"(gene name)|psi-mi:"E(spl)m7-HLH"(display_short)|uniprotkb:HLHm7(gene name synonym)|uniprotkb:CG8361(orf name) psi-mi:"MI:0018"(two hybrid) Trott et al. (2001) pubmed:11208814|mint:MINT-5213561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773813|mint:MINT-13730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N|mint:MINT-468435(identity) refseq:NP_536753.1|flybase:FBgn0002633|dip:DIP-626N|ensemblmetazoa:FBgn0002633(gene)|ensemblmetazoa:FBtr0084960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-468441(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/06/04 2014/10/16 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 rogid:ko+76awzLWRJNBn06B3PQZWBhf47227 intact-crc:39703168685D7B5F|rigid:TlF6WY6a0g+gGSobp3P9FxRNOsU false tag:?-?(MINT-468436) tag:?-?(MINT-468442) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13096 uniprotkb:P08181 intact:EBI-104760|intact:EBI-1639197|uniprotkb:Q9VBI8|uniprotkb:Q56K28|uniprotkb:Q56K51|uniprotkb:Q56K70|uniprotkb:Q56K88|uniprotkb:Q56K96|uniprotkb:Q56KF0|uniprotkb:Q56KF1|uniprotkb:Q56KG3|uniprotkb:Q56KH0|uniprotkb:Q56KI0|uniprotkb:Q56KJ4|uniprotkb:Q56KK0|uniprotkb:Q56KQ1|uniprotkb:Q56KQ5|uniprotkb:Q56KS5|uniprotkb:Q56KV2|uniprotkb:Q56KV5|uniprotkb:Q56KV7|uniprotkb:Q56KW6|uniprotkb:Q56KX1|uniprotkb:Q56KZ8|uniprotkb:Q5S489|uniprotkb:Q5S4I5|uniprotkb:Q5S4J7|ensemblmetazoa:FBpp0084352 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:esm5_drome(display_long)|uniprotkb:"E(spl)m5-HLH"(gene name)|psi-mi:"E(spl)m5-HLH"(display_short)|uniprotkb:HLHm5(gene name synonym)|uniprotkb:CG6096(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0018"(two hybrid) Trott et al. (2001) pubmed:11208814|mint:MINT-5213561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773861|mint:MINT-16019 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524511.1|flybase:FBgn0002631|dip:DIP-627N|ensemblmetazoa:FBgn0002631(gene)|ensemblmetazoa:FBtr0084979(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-468471(identity) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N|mint:MINT-468465(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/06/04 2014/10/16 rogid:UP+P9xXX98OeDVDxA1ePXRWmaXs7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:69507FC6E4E8110C|rigid:yBXkcyljNn1Wij84yFWLdRmWm70 false tag:?-?(MINT-468472) tag:?-?(MINT-468466) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13098 uniprotkb:P08181 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0018"(two hybrid) Trott et al. (2001) pubmed:11208814|mint:MINT-5213561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7773845|mint:MINT-17271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-468456(identity) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N|mint:MINT-468450(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:CKII binds and phosphorylaes m8 on Ser159. Changing Ser into Ala binding is decresed. By changing Ser into Asp, binding is abolished.|comment:mint taxid:-4(in vivo)|taxid:-4(in vivo) - 2001/06/04 2014/10/16 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:E5AD7D196D835D58|rigid:jm4iqqbCe8IB3dyz972letTG8ws false tag:?-?(MINT-468457) tag:?-?(MINT-468451) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P13098 uniprotkb:P08181 intact:EBI-185388|intact:EBI-1639218|uniprotkb:Q9VBI5|uniprotkb:Q0IGQ3|uniprotkb:Q2XYK0|uniprotkb:Q5S426|uniprotkb:Q5S462|uniprotkb:Q5S474|uniprotkb:Q5S4H0|uniprotkb:Q5S4I2|ensemblmetazoa:FBpp0084335 intact:EBI-93115|uniprotkb:Q0E8B4|uniprotkb:Q9W5T2|ensemblmetazoa:FBpp0070041|ensemblmetazoa:FBpp0070042|ensemblmetazoa:FBpp0070043|ensemblmetazoa:FBpp0110433|ensemblmetazoa:FBpp0311229|ensemblmetazoa:FBpp0311359|ensemblmetazoa:FBpp0311360 psi-mi:esm8_drome(display_long)|uniprotkb:"E(spl)m8-HLH"(gene name)|psi-mi:"E(spl)m8-HLH"(display_short)|uniprotkb:"E(spl)"(gene name synonym)|uniprotkb:m8(gene name synonym)|uniprotkb:CG8365(orf name) psi-mi:csk2a_drome(display_long)|uniprotkb:CkIIalpha(gene name)|psi-mi:CkIIalpha(display_short)|uniprotkb:Cask-II-a(gene name synonym)|uniprotkb:CG17520(orf name) psi-mi:"MI:0424"(protein kinase assay) Trott et al. (2001) pubmed:11208814|mint:MINT-5213561 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7773901|mint:MINT-16641 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524513.1|flybase:FBgn0000591|dip:DIP-22511N|ensemblmetazoa:FBgn0000591(gene)|ensemblmetazoa:FBtr0084961(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007498"(mesoderm development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016360"(sensory organ precursor cell fate determination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048749"(compound eye development)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|interpro:IPR003650(Orange)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:MINT-468487(identity) refseq:NP_001287151.1|refseq:NP_001287152.1|refseq:NP_001287153.1|refseq:NP_524918.1|refseq:NP_730774.1|refseq:NP_730775.1|ensemblmetazoa:FBgn0264492(gene)|ensemblmetazoa:FBtr0070042(transcript)|ensemblmetazoa:FBtr0070043(transcript)|ensemblmetazoa:FBtr0070044(transcript)|ensemblmetazoa:FBtr0111141(transcript)|ensemblmetazoa:FBtr0344974(transcript)|ensemblmetazoa:FBtr0345138(transcript)|ensemblmetazoa:FBtr0345139(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002118"(aggressive behavior)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007310"(oocyte dorsal/ventral axis specification)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0022416"(chaeta development)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0046331"(lateral inhibition)|go:"GO:0048749"(compound eye development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060810"(intracellular mRNA localization involved in pattern specification process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-DME-201688|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-2514853|reactome:R-DME-432553|reactome:R-DME-6804756|reactome:R-DME-6814122|reactome:R-DME-8934903|reactome:R-DME-8948751|refseq:NP_001036624.1|flybase:FBgn0264492|dip:DIP-18339N|mint:MINT-468482(identity) - comment:"Stoichiometry: 1.0" comment:"Stoichiometry: 1.0" comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2001/06/04 2014/10/16 rogid:Ytd8Ad4FJAfx25V7mHNi9e+F0pw7227 rogid:0wrL1LjHFiPEQg3UxDl917ya/qg7227 intact-crc:3FB0A59BC9088245|rigid:jm4iqqbCe8IB3dyz972letTG8ws false tag:?-?(MINT-468488) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)