ESP1
ESPL1
KIAA0165
UniProt:Q14674 ESPL1
Association of Securin with Cdc20:APC/C complex
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex
Degradation of multiubiquitinated Securin
PTTG1 (Securin) sequesters ESPL1 (Separase)
Securin sequesters Separase
Autocleavage of ESPL1 (Separase)
Autocleavage of Separin
ESPL1 (Separase) cleaves centromeric cohesin
Separation of sister chromatids
Deacetylation of cleaved cohesin
Separation of Sister Chromatids