MT4033
Rv3914
trx
trxA
trxC
MT2272
Rv2215
UniProt:P65633 dlaT
dlaT
sucB
MT0797
Rv0773c
ggt-1
ggtA
MT0420
Rv0407
UniProt:P96253 fgd1
fgd
fgd1
Carboxymycobactin binds iron from lactoferrin
Nitrogen dioxide is reduced to NO by F420
Nitric oxide is oxidized to nitrate
Peroxynitrite is reduced to nitrite by AhpC
Peroxynitrite is reduced by AhpE
Peroxynitrite is reduced to nitrite by Tpx
Mycothiol scavenges nitrosyl
MscR reduces nitrosomycothiol to ammonia
MsrA/B reduces peptide-methionine S/R-sulfoxides
Nitrosoglutathione gets cleaved to Cys(NO)-Gly
SodB gets secreted
SodB reduces superoxide to H2O2
SodC reduces superoxide to H2O2
AhpC reduces H2O2
KatG reduces H2O2
H2O2 gets scavenged by unsaturated lipid
AhpC reduces peroxidated lipids
AhpD reactivates AhpC
DlaT reactivates AhpD
Lpd reactivates dlaT
TrxA reactivates AhpC
TrxB reactivates TrxA
TrxA/B1 reactivates Tpx
Fgd1 reactivates F420
Carboxymycobactin gets secreted
Mycobactin is exported
Carboxymycobactin and mycobactin exchange their iron load
Loaded mycobactin gets imported
Iron is reduced and separates from mycobactin
BfrA stores iron
BfrB stores iron
Response of Mtb to phagocytosis
Tolerance by Mtb to nitric oxide produced by macrophages
Tolerance of reactive oxygen produced by macrophages
Cell redox homeostasis
Mtb iron assimilation by chelation