C3 convertases spontaneously dissociate
Factor H binds to C3b
Factor H binds host cell surface markers
Factor H binds to membrane-associated C3b
Factor H binds to C3bBb
Factor H displaces Bb
Complement factor I complex formation
Complement factor I binds to extracellular Factor H:C3b
Factor I inactivates plasma Factor H-bound C3b
Complement factor I binds to membrane-associated Factor H:C3b
Factor I inactivates Factor H-boundC3b
iC3b proteolysis
CR1 binds C3bBb/C4bC2a
Displacement of C2a/Bb by CR1
MCP binds C3b, C4b
Complement factor I binds to MCP, CR1:C4b, C3b
Factor I inactivates MCP/CR1-bound C4b/C3b
DAF binds C3bBb, C4bC2a
DAF accelerates C3bBb/C4bC2a dissociation
C4b-binding protein binds C4b
Complement factor I binds C4BP
Complement factor I inactivates C4BP-bound C4b
C4b binding protein binds C4bC2a
C4b binding protein displaces C2a
C4b binding protein binds Protein S
CD59 inhibits MAC formation
Formation of soluble VTN:C5b-C9
Vitronectin(VTN) binds to C5b:C6:C7
Hydrolysis of internal thioester in C4b
Regulation of Complement cascade