FUR
FURIN
PACE
PCSK3
UniProt:P09958 FURIN
C3orf9
CLP46
KTELC1
MDS010
MDSRP
POGLUT1
UniProt:Q8NBL1 POGLUT1
FUT12
KIAA0180
POFUT1
UniProt:Q9H488 POFUT1
NOTCH1 gene transcription
NOTCH2 gene transcription
NOTCH3 gene transcription
NOTCH4 gene transcription
p53 positively regulates transcription of MIR34 microRNAs
MIR34 microRNAs bind 3'UTR of NOTCH1 mRNA
MIR200B/C microRNAs bind NOTCH1 mRNA
MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA
MIR34 microRNAs bind 3'UTR of NOTCH2 mRNA
MIR150 microRNA binds 3'UTR of NOTCH3 mRNA
MIR206 microRNA binds 3'UTR of NOTCH3 mRNA
MIR181C microRNA binds 3'UTR of NOTCH4 mRNA
MIR302A microRNA binds 3'UTR of NOTCH4 mRNA
NOTCH1 mRNA translation controlled by miRNAs
NOTCH2 mRNA translation controlled by miRNAs
NOTCH3 mRNA translation controlled by miRNAs
NOTCH4 mRNA translation controlled by miRNAs
Fucosylation of Pre-NOTCH by POFUT1
Glucosylation of Pre-NOTCH by POGLUT1
Transport of NOTCH precursor to Golgi
NOTCH precursor cleaved to form mature NOTCH
Glycosylation of Pre-NOTCH by FRINGE
Galactosylation of Pre-NOTCH
Sialylation of Pre-NOTCH
Fringe-modified Pre-NOTCH is cleaved by FURIN
Mature NOTCH heterodimer traffics to the plasma membrane
Transport of fringe-modified NOTCH to plasma membrane
Pre-NOTCH Expression and Processing
Pre-NOTCH Transcription and Translation
Pre-NOTCH Processing in the Endoplasmic Reticulum
Pre-NOTCH Processing in Golgi