JAK2 phosphorylation
PRLR associates with JAK2
PRLR:JAK2 dimerizes
Prolactin receptor ligands bind the prolactin receptor
PRLR activation
SH2B binds JAK2
Tyrosine phosphorylation of PRLR
PRLR binds STAT5
PRLR-bound STAT5 is phosphorylated
PRLR binds SHP2 (PTPN11)
SHP2 is phosphorylated
PRLR is phosphorylated at Ser-349
PRLR binds SCF beta-TrCP complex
Prolactin receptor is internalized
Cleavage of P-ERBB4jmA isoforms by ADAM17
Cleavage of ERBB4m80 by gamma-scretase complex
Translocation of ERBB4s80 to the nucleus
ERBB4s80 binds TAB2:NCOR1 complex
ERBB4:TAB2:NCOR1 complex translocates to the nucleus
Transcription of GFAP and S100B
WWOX binds ERBB4s80
ERBB4s80 binds YAP1
Translocation of ERBB4s80:YAP1 complex to the nucleus
ERBB4s80 binds STAT5A
ERBB4s80:STAT5A complex translocates to the nucleus
ERBB4s80 forms a complex with estrogen receptor ESR1
Transcription of NR3C3 and CXCL12
Translocation of cytosolic ERBB4s80 to mitochondrial matrix
Nuclear signaling by ERBB4
Prolactin receptor signaling
Transcription of beta-casein (CSN2)